II. Epidemiology
- Since Rotavirus Vaccine was initiated in 2006 in U.S., cases have fallen as much as 90%
- Prior to Rotavirus Vaccine starting in 2006, was the most common cause of Acute Infectious Diarrhea in the U.S.
- Accounted for 35% of child hospitalizations for Diarrhea
- Hospitalizations: 55,000 to 70,000 per year in United States
- Mortality: 20-60 deaths per year in United States
- Worldwide Rotavirus still kills more than 400,000 children under age 5 years old
- Peak ages affected: 6 months to 2 years old
- Uncommon under age 6 months or over age 4 years
- Infection peaks in March (mid-January to late May)
III. Pathophysiology
- Antibody to Rotavirus is protective
- Self limited Infection
- Transmission: Fecal-oral route
- Incubation: 1-3 days
V. Prevention
- Careful Hand Washing
- See Rotavirus Vaccine
- Limited use due to Intussusception risk
VI. Resources
- CDC Rotavirus