II. Epidemiology
- Outbreaks related to contaminated swimming pools or shared pool towels
- Consider as cause with outbreaks in young children
III. Pathophysiology
- Adenoviridae (Adenovirus)
- Nonenveloped (naked)
- Icosahedral capsid
- Medium-sized (90-100 nm)
- Initial identification was from an adenoid sampling (resulting in the name Adenovirus)
- Adenoviridae contain a single, linear dsDNA
- Human Adenovirus fall into the genus Mastadenovirus
- Mastadenovirus genus contains 7 Species (A-G) with >80 total serotypes
- Manifestations (URI, Conjunctivitis, Diarrhea) are specific to the species and serotypes
IV. Symptoms
-
Fever
- Peaks to 103-104 F (39.4-40.0 C)
- Chills
- Myalgias
- Sore Throat
V. Signs
-
Conjunctivitis
- Most common cause of Viral Conjunctivitis in children
- Unilateral follicular Conjunctivitis is most common
- Associated with Adenovirus Pharyngitis in 30-50% of cases
-
Pharyngitis
- Tonsillar exudates may be present
-
Diarrhea
- More prolonged course than Rotavirus
VI. Differential Diagnosis
VII. Course
- Clears in 4-5 days
VIII. Resources
- Adenoviridae (wikipedia)