II. Preparation: Components of Twinrix Vaccine

  1. Killed Hepatitis A Virus and
  2. Recombinant Hepatitis B

III. Dosing

  1. Adults: 720 EU/20 ug (1.0 ml)
  2. Standard 3 dose series (same schedule as Hepatitis B Vaccine schedule)
    1. Dose 1: Month 0
    2. Dose 2: Month 1
    3. Dose 3: Month 6
  3. Alternative accelerated 4 dose series
    1. Dose 1: Day 0
    2. Dose 2: Day 7
    3. Dose 3: Day 21-30
    4. Dose 4: Month 12

IV. Contraindications

  1. Not approved for use in Children (age <18 years)

V. Resources

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