II. Definition
- Tuberculosis Vaccine commonly used outside of U.S.
III. Indications
-
General
- Routinely given to children in Tb endemic regions
- Not typically used in the United States
- Use directed by local Tuberculosis control program
- May be indicated in young children at high risk for Tb
- Consider for frequent exposure to Active Tuberculosis
- See efficacy below regarding use in young children
IV. Background
- Live Attenuated Vaccine with Mycobacterium bovis
V. Adverse effects
- Disseminated disease in immunodeficient patients
VI. Efficacy
- BCG may reduce severe disseminated Tb in young children
- BCG vaccine protects against infection in children