II. Indications
- Prevention of Vibrio Cholera O1 in adults travelling to Cholera-affected areas
III. Preparations
- Lypholized CVD 103-HgR (Vaxchora, PaxVax)
- Single dose, live attenuated, oral Cholera Vaccine
- Only FDA approved Cholera Vaccine in U.S. (approved in 2016)
- Efficacy beyond 3 months is not known as of late 2017
- Avoid use of Antibiotics in the 14 days preceding Cholera Vaccine
- Delay starting Chloroquine for at least 10 days after oral Cholera Vaccine
- Delay taking oral Typhoid Vaccine by at least 8 hours after oral Cholera Vaccine
- Likely safe in HIV Infection (but lower seroconversion rate)
- Like safe in pregnancy as no systemic absorption (however Vaccine is shed for 7 days)
- Killed Cholera Vaccine
- Older intradermal Vaccine, 0.2 ml IM given at time 0, 1-4 weeks and then every 6 months as needed
- Protection of 30-50% lasts only 6 months
- Safe in Human Immunodeficiency Virus (HIV)
- Do not use in pregnancy
IV. References
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Definition (HL7V3.0) | <p>cholera vaccine</p> |
Definition (MSH) | Vaccines or candidate vaccines used to prevent infection with VIBRIO CHOLERAE. The original cholera vaccine consisted of killed bacteria, but other kinds of vaccines now exist. |
Definition (CSP) | vaccines or candidate vaccines used to prevent infection with Vibrio cholerae. |
Concepts | Pharmacologic Substance (T121) , Immunologic Factor (T129) |
MSH | D022121 |
SnomedCT | 35736007, 396422009 |
CPT | 90725 |
HL7 | 26 |
English | Cholera Vaccine, cholera vaccine, Cho/Vac, cholera vaccine (medication), Cholera Vaccines [Chemical/Ingredient], cholera vaccines, vaccine cholera, Cholera Vaccines, Vaccines, Cholera, Cholera vaccine, Cholera vaccine (product), Cholera vaccine (substance), Cholera vaccines, cholera, Cholera |
Swedish | Koleravacciner |
Czech | cholerové vakcíny |
Finnish | Kolerarokotteet |
Russian | VAKTSINY KHOLERNYE, VAKTSINA KHOLERNAIA, KHOLERNAIA VAKTSINA, KHOLERNYE VAKTSINY, ВАКЦИНА ХОЛЕРНАЯ, ВАКЦИНЫ ХОЛЕРНЫЕ, ХОЛЕРНАЯ ВАКЦИНА, ХОЛЕРНЫЕ ВАКЦИНЫ |
Polish | Szczepionki przeciw cholerze |
Portuguese | Vacinas Anticólera, Vacinas de Cólera, Vacinas contra Cólera |
Spanish | vacuna anticólera, vacuna contra el cólera (producto), vacuna contra el cólera (sustancia), vacuna contra el cólera, Vacunas contra el Cólera |
French | Vaccins anticholériques |
German | Cholera-Vakzinen, Vakzinen, Cholera- |
Italian | Vaccini colerici |