II. Pathophysiology
- Irregularly shaped Bacteria in the genus Mycoplasma, that lacks a cell wall (Penicillin resistant)
- Colonizes as well as causes symptomatic urogenital, oral and anal infections (sexually transmitted)
- Four serovars (1, 3, 6, and 14) were previously classified as Ureaplasma Urealyticum, but arre now classified as Ureaplasma Parvum
- May be associated with Mycoplasma Genitalium infections
III. Risk Factors
IV. Labs
- Difficult to culture (fastidious)
- PCR testing availability is increasing
- Urethal swabs are preferred
V. Management
- Primary Antibiotic Regimens (adult dosing)
- Doxycycline 100 mg orally or IV every 12 hours for 7 to 14 days
- Alternative Antibiotic Regimens (adult dosing)
- Azithromycin 500 mg orally or IV for 10 to 14 days OR
- Levofloxacin 500 mg orally or IV daily for 10 to 14 days OR
- Moxifloxacin 400 mg orally or IV daily for 10 to 14 days
VI. Complications
- Infertility secondary to pelvic infections (Pelvic Inflammatory Disease)
- Pregnancy loss or premature labor
- Neonatal Sepsis, Pneumonia and Meningitis may occur
- Other infections include Septic Arthritis, Osteomyelitis, Pneumonia, endocarditis
- Hyperammonemia Syndrome (Immunocompromised patients, esp. lung transplant)
VII. References
- (2024) Ureaplasma Urealyticum, Sanford Guide, accessed on IOS, 5/5/2024
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Definition (NCI_CDISC) | Any bacterial organism that can be assigned to the species Ureaplasma urealyticum. |
Definition (NCI) | A species of irregularly shaped bacteria that does not contain a cell well in the phylum Tenericutes. This species is urease and acid phosphatase positive and hexokinase and catalase negative; sterols are required for growth. U. urealyticum resides in the genital flora of humans and may be a cause of urogenital infections. |
Definition (MSH) | A species of gram-negative bacteria found in the human genitourinary tract (UROGENITAL SYSTEM), oropharynx, and anal canal. Serovars 1, 3, 6, and 14 have been reclassed into a separate species UREAPLASMA parvum. |
Concepts | Bacterium (T007) |
MSH | D016990 |
SnomedCT | 12006007 |
LNC | LP19253-1, MTHU007821, LA18630-6 |
English | Ureaplasma urealyticum, Ureaplasma urealyticum (bacteria), Ureaplasma urealyticum Shepard et al. 1974 (Approved Lists 1980) emend. Robertson et al. 2002, T-Mycoplasma, ureaplasma urealyticum, urealyticum ureaplasma, Ureaplasma urealyticum biovar 2, T-MYCOPLASMA, UREAPLASMA UREALYTICUM, T-mycoplasma, Ureaplasma urealyticum (organism) |
French | Ureaplasma urealyticum biovar 2, Ureaplasma urealyticum |
Swedish | Ureaplasma urealyticum |
Czech | Ureaplasma urealyticum |
Finnish | Ureaplasma urealyticum |
Japanese | ウレアプラズマ・ウレアリティカム |
Croatian | UREAPLASMA UREALYTICUM |
Polish | Ureaplasma urealyticum |
Norwegian | Ureaplasma urealyticum biovar 2, Ureaplasma urealyticum |
Spanish | Ureaplasma urealyticum (organismo), Ureaplasma urealyticum |
German | Ureaplasma urealyticum |
Italian | Ureaplasma urealyticum |
Russian | UREAPLASMA UREALYTICUM |
Dutch | Ureaplasma urealyticum |
Portuguese | Ureaplasma urealyticum |
Ontology: Ureaplasma parvum (C1065064)
Definition (MSH) | A species of UREAPLASMA containing four serovars formerly classed as UREAPLASMA UREALYTICUM. Those serovars are 1, 3, 6, and 14. |
Concepts | Bacterium (T007) |
MSH | D014509 |
SnomedCT | 438391000 |
LNC | LP145575-9, LA19122-3 |
French | Ureaplasma urealyticum biovar 1, Ureaplasma parvum |
Portuguese | Ureaplasma parvum |
German | Ureaplasma parvum, Ureaplasma urealyticum biovar 1 |
English | Ureaplasma parvum (organism), Ureaplasma parvum Robertson et al. 2002, Ureaplasma urealyticum biovar 1, Ureaplasma parvum |
Spanish | Ureaplasma parvum, Ureaplasma parvum (organismo) |
Italian | Ureaplasma parvum, Ureaplasma urealyticum biovar 1 |
Norwegian | Ureaplasma urealyticum biovar 1, Ureaplasma parvum |
Dutch | Ureaplasma parvum |