II. Mechanism
- Neutrophil Granulocytes contain esterases
- Positive test suggests pyuria
- Dipstick requires 5 minutes to change color
III. Normal
- Negative
IV. Abnormal: Positive
- Urinary Tract Infection
- Vaginal contaminant
V. Causes: False negative Leukocyte esterase on Urinalysis
- Inadequate time allowed for dipstick reading
- Increased Urine Specific Gravity
- Urine Glucose present (Glycosuria)
- Urine Ketones present (Ketonuria)
- Proteinuria
- Keflex
- Nitrofurantoin
- Tetracycline
- Gentamicin
- Vitamin C
VI. Causes: Positive Leukocyte esterase and negative culture
- Chlamydia
- Ureaplasma urealyticum
- Balanitis
- Bladder Cancer
- Nephrolithiasis
- Tuberculosis
- Urinary tract foreign body
- Glomerulonephritis
- Medications (Corticosteroid, Cytoxan)
- Methenamine
