II. Definitions
- Cephamycin
- Naturally occurring beta lactam Cephalosporins with a 7-methoxy group
- Activity against Gram Positive and Gram Negative Bacteria, and resistance to Beta Lactamases
III. Mechanism
- Antibiotics in this group are Cephamycin derivatives
-
Antibiotic coverage spectrum
- Gram Positive activity (but less than Second Generation Broad-spectrum Cephalosporins such as Cefuroxime)
- Gram Negative coverage
- Anaerobic coverage (e.g. Bacteroides)
IV. Indications
- Abdominal Surgery prophylaxis
- Colorectal surgery prophylaxis
V. Medications
VI. References
- (2012) Presc Lett, Resource #280706, Comparison of Cephalosporins
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Related Studies
| Definition (NCI) | A second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole is active against Haemophilus and gram-negative bacilli susceptible to other cephalosporins. It is also active against many strains resistant to other cephalosporins, such as Enterobacter species and indole-positive Proteus species. |
| Definition (MSH) | Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as the nafate. |
| Concepts | Antibiotic (T195) , Organic Chemical (T109) |
| MSH | D002435 |
| SnomedCT | 372801003, 61651006 |
| LNC | LP16064-5, MTHU008441 |
| English | Cefamandole, Cephamandole, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((hydroxyphenylacetyl)amino)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7beta(R*)))-, cefamandole, (6R,7R)-7-(R)-Mandelamido-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-carboxylic Acid, Cefamandole [Chemical/Ingredient], Cefamandole (product), Cefamandole (substance), cephamandole, CEFAMANDOLE |
| Swedish | Cefamandol |
| Czech | cefamandol |
| Finnish | Kefamandoli |
| Russian | TSEFAMANDOL, ЦЕФАМАНДОЛ |
| Japanese | セファマンドール |
| Croatian | CEFAMANDOL |
| Polish | Cefamandol |
| Spanish | cefamandol (producto), cefamandol (sustancia), cefamandol, Cefamandol |
| French | Céfamandole |
| German | Cefamandol |
| Italian | Cefamandolo |
| Portuguese | Cefamandol |
Ontology: Cephamycins (C0007736)
| Definition (MSH) | Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms. |
| Concepts | Antibiotic (T195) , Organic Chemical (T109) |
| MSH | D002513 |
| SnomedCT | 350138008, 416147006 |
| English | Cephamycins, Antibiotics, Cephamycin, Cephamycin Antibiotics, Cephamycins [Chemical/Ingredient], cephamycin, cephamycins, Cephamycin, Cephamycin (product), Cephamycin (substance), Cefamycin |
| Swedish | Cefamyciner |
| Czech | cefamyciny |
| Finnish | Kefamysiinit |
| Russian | TSEFAMITSINY, ЦЕФАМИЦИНЫ |
| Polish | Cefamycyny |
| Japanese | セファマイシン, 抗生物質-セファマイシン系, セファマイシン系抗生物質 |
| Spanish | cefamicina (producto), cefamicina, cefamicina (sustancia), Cefamicinas, Antibióticos Cefamicinos |
| French | Céfamycines |
| German | Antibiotika, Cephamycin-, Cephamycine |
| Italian | Cefamicine |
| Portuguese | Antibióticos Cefamicina, Cefamicinas |
