Mebendazole

Aka: Mebendazole, Emverm, Vermox

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II. Medications

  1. Chewable Tablets: 100 mg
    1. In U.S., Vermox was original trade name (in 2016 was rebranded as Enverm)

III. Indications

  1. Pinworm
  2. Roundworm
  3. Whipworm
  4. Hookworm

IV. Mechanism

  1. Synthetic benzimidazole derivate
  2. Inhibits Helminth (worm) reproduction and survival
    1. Blocks microtubule formation (polymerization) in cytoplasm
    2. Blocks Glucose uptake and depletes Helminth glycogen stores
    3. Results in reduced ATP and Helminth death

V. Dosing: Adults and Children

  1. Doses for adults and children are the same
  2. Pinworm
    1. Mebendazole 100 mg orally for a single dose, and repeat in 2 weeks
  3. Roundworm, Hookworm or Whipworm
    1. Mebendazole 100 mg orally twice daily for 3 days OR
    2. Mebendazole 500 mg orally twice daily for one dose (off label)

VI. Safety

  1. Unknown safety in first trimester (may be used in later pregnancy)
  2. Considered safe in Lactation

VII. Resources

  1. Mebendazole (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a8c46363-f739-4f6e-bca8-1ce5e8d3f78d

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Related Studies

Cost: Medications

emverm (on 2/1/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
EMVERM 100 MG TABLET CHEW $538.55 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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