II. Pathophysiology

  1. Drugs are second most common cause of Neutropenia
  2. Induce hypoproliferation via marrow injury

III. Causes: Most common

  1. Chemotherapeutics (standard effect, see below)
  2. Thyroid inhibitors (Antithyroid Drugs)
  3. Trimethoprim-Sulfamethoxazole (Septra, Bactrim)
  4. Sulfasalazine
  5. Clomipramine
  6. Dipyrone
  7. Concurrent Analgesic use is predisposing factor

VIII. Causes: Analgesics

IX. Causes: Miscellaneous

X. References

  1. Lee (1999) Wintrobe's Hematology, Lippincott, p. 1862-9
  2. van der Klauw (1999) Arch Intern Med 159(4):369-74 [PubMed]

Images: Related links to external sites (from Bing)

Related Studies