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Ontology:
tirofiban
(C0247025)
| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
| MSH |
C078823
|
| SnomedCT |
108981004, 386953003 |
| LNC |
LP171644-0 |
| English |
N-(butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosine, tirofiban, tirofiban (medication), tirofiban [Chemical/Ingredient], TIROFIBAN, Tirofiban (product), Tirofiban (substance), Tirofiban |
| Spanish |
tirofibán (producto), tirofibán (sustancia), tirofibán |
Ontology:
eptifibatide
(C0253563)
|
Definition (NCI)
|
A cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development.
|
| Concepts |
Pharmacologic Substance
(T121)
, Amino Acid, Peptide, or Protein
(T116)
|
| MSH |
C086648
|
| SnomedCT |
116065005, 386998009 |
| LNC |
LP171395-9 |
| English |
L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic(1-6)-disulfide, eptifibatide, eptifibatide (medication), eptifibatide [Chemical/Ingredient], Eptifibatide (product), Eptifibatide (substance), Eptifibatide, epifibatide, epifibratide, EPTIFIBATIDE |
| Japanese |
エプチフィバチド
|
| Spanish |
eptifibatida (producto), eptifibatida (sustancia), eptifibatida |
Ontology:
abciximab
(C0288672)
|
Definition (NCI)
|
A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation.
|
| Concepts |
Immunologic Factor
(T129)
, Amino Acid, Peptide, or Protein
(T116)
, Pharmacologic Substance
(T121)
|
| MSH |
C085843
|
| SnomedCT |
391697004, 386951001, 108974006 |
| LNC |
LP171382-7 |
| English |
abciximab, abciximab (medication), MoAb 7E3, Chimeric 7E3 Fab, abciximab [Chemical/Ingredient], Abciximab - chemical (substance), Abciximab - chemical, Abciximab, Abciximab (product), Abciximab (substance), c7E3 Fab, chimeric 7E3 Fab, ABCIXIMAB |
| Spanish |
abciximab (producto), abciximab (sustancia), abciximab |
Ontology:
ReoPro
(C0592046)
| Concepts |
Pharmacologic Substance
(T121)
, Amino Acid, Peptide, or Protein
(T116)
|
| MSH |
C085843
|
| English |
ReoPro, Reopro, reopro, Eli Lilly brand of abciximab, Lilly brand of abciximab |
Ontology:
Aggrastat
(C0656369)
| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
| MSH |
C078823
|
| English |
Aggrastat, aggrastat, Cahill May Roberts brand of tirofiban hydrochloride monohydrate, MSD brand of tirofiban hydrochloride monohydrate, Merck Frosst brand of tirofiban hydrochloride monohydrate, Merck Sharp & Dohme brand of tirofiban hydrochloride monohydrate, Merck brand of tirofiban hydrochloride monohydrate, Agrastat |
Ontology:
Integrilin
(C0950902)
| Concepts |
Pharmacologic Substance
(T121)
, Amino Acid, Peptide, or Protein
(T116)
|
| MSH |
C086648
|
| English |
Integrilin, eptifibatide (Integrilin), Integrelin, Pfizer brand of eptifibatide, GlaxoSmithKline UK brand of eptifibatide, integrelin, integrilin, Cor brand of eptifibatide, Essex brand of eptifibatide, Key brand of eptifibatide |
