Definition (NCI)
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This protein is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. The gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. (from LocusLink)
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Definition (NCI)
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An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
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Definition (NCI_NCI-GLOSS)
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A substance that helps make more white blood cells, especially granulocytes, macrophages, and cells that become platelets. It is a cytokine that is a type of hematopoietic (blood-forming) agent.
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Definition (MSH)
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An acidic glycoprotein of MW 23 kDa with internal disulfide bonds. The protein is produced in response to a number of inflammatory mediators by mesenchymal cells present in the hemopoietic environment and at peripheral sites of inflammation. GM-CSF is able to stimulate the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from fetal liver progenitor cells. GM-CSF can also stimulate some functional activities in mature granulocytes and macrophages.
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Concepts |
Amino Acid, Peptide, or Protein
(T116)
, Immunologic Factor
(T129)
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MSH |
D016178
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SnomedCT |
53681007
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English |
Cell-Stimulating Factor, Histamine-Producing, Colony Stimulating Factor, Granulocyte Macrophage, Colony-Stimulating Factor, Granulocyte-Macrophage, CSF-2, CSF-GM, GM-CSF, Histamine Producing Cell Stimulating Factor, Histamine-Producing Cell-Stimulating Factor, TC-GM-CSF, Tumor-Cell Human GM Colony-Stimulating Factor, Colony-stimulating factor 2, GMCSF, granulocyte-macrophage colony stimulating factor, GRANULOCYTE MACROPHAGE COLONY A STIMULATING FACTOR, histamine producing cell stimulating factor, GMCSF (granulocyte macrophage colony stimulating factor), Granulocyte-Macrophage Colony-Stimulating Factor [Chemical/Ingredient], gm-cfs, gmcsf, gm-csf, gm csf, Tumor Cell Human GM Colony Stimulating Factor, granulocyte macrophage colony stimulating factor, Granulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, Colony-stimulating factor, granulocyte-macrophage, Colony-stimulating factor, granulocyte-macrophage (substance), Granulocyte-Macrophage Colony-Stimulating Factor, granulocyte macrophage colony-stimulating factor, CSF, Colony-Stimulating Factor, GM CSF, Granulocyte Macrophage Colony Stimulating Factor, Granulocyte-Macrophage Colony Stimulating Factor, Colony Stimulating Factor 2, Colony Stimulating Factor, Granulocyte-Macrophage, Granulocyte Macrophage Colony-Stimulating Factor, CSF2, Granulocyte macrophage colony stimulating factor |
Swedish |
Granulocyt-makrofagkolonistimulerande faktor
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Czech |
faktor stimulující granulocyto-makrofágové kolonie
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Finnish |
Granulosyytti-makrofagikasvutekijä
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French |
Facteur de croissance des granulocytes et macrophages, Facteur stimulant la formation de colonies de neutrophiles et de macrophages, Facteur stimulant les colonies de granulocytes et de macrophages, Facteur stimulant les colonies de granulocytes-macrophages, Facteur stimulant la formation de colonies de granulocytes et de macrophages, Facteur de stimulation des colonies de granulocytes et de macrophages, Facteur de croissance des colonies granulocytaires et macrophagiques, GM-CSF, GMCSF, Facteur de croissance des granulocytes-macrophages, Facteur de croissance granulocyto-monocytaire |
Russian |
GRANULOTSIT-MAKROFAGOV KOLONIESTIMULIRUIUSHCHII FAKTOR, GM-KSF, GISTAMIN-PRODUTSIRUIUSHCHIE KLETKI, STIMULIRUIUSHCHII FAKTOR, KOLONIESTIMULIRUIUSHCHII FAKTOR GRANULOTSIT-MAKROFAGOV, KSF-GM, GM-KSF REKOMBINANTNYI, ГРАНУЛОЦИТОВ МАКРОФАГОВ КОЛОНИЕСТИМУЛИРУЮЩИЕ ФАКТОРЫ РЕКОМБИНАНТНЫЕ, GRANULOTSITOV MAKROFAGOV KOLONIESTIMULIRUIUSHCHIE FAKTORY REKOMBINANTNYE, ГМ-КСФ РЕКОМБИНАНТНЫЙ, CSF-GM, GM-CSF, ГИСТАМИН-ПРОДУЦИРУЮЩИЕ КЛЕТКИ, СТИМУЛИРУЮЩИЙ ФАКТОР, ГМ-КСФ, ГРАНУЛОЦИТ-МАКРОФАГОВ КОЛОНИЕСТИМУЛИРУЮЩИЙ ФАКТОР, КОЛОНИЕСТИМУЛИРУЮЩИЙ ФАКТОР ГРАНУЛОЦИТ-МАКРОФАГОВ, КСФ-ГМ |
Japanese |
顆粒球・マクロファージコロニー刺激因子, 顆粒球マクロファージコロニー刺激因子, 顆粒球-マクロファージコロニー刺激因子, ヒスタミン産生細胞刺激因子, 顆粒球マクロファージコロニー形成刺激因子 |
Spanish |
Factor Estimulante de Colonias de Granulocitos y Macrófagos, Factor Estimulante de Colonias de Macrófagos y Granulocitos, CSF - GM, factor estimulante de formación de colonias, granulocito - macrófago (sustancia), factor estimulante de formación de colonias, granulocito - macrófago, CSF-GM, GM-CSF, Factor de Célula Estimulante Productora de Histamina |
German |
GRANULOZYTEN MAKROPHAGEN KOLONIE A STIMULIERENDER FAKTOR, CSF-GM, GM-CSF, Granulozyten-Makrophagen-Kolonien-stimulierender Faktor, Histamin-produzierende Zellen-stimulierender Faktor, Kolonien-stimulierender Faktor, Granulozyten-Makrophagen- |
Portuguese |
Fator Estimulador de Colônias de Macrófagos e Granulócitos, Fator Estimulador de Colônias de Granulócitos e Macrófagos, CSF-GM, GM-CSF, Fator Estimulador de Células para Produção de Histamina |
Croatian |
GRANULOCITNO-MAKROFAGNE KOLONIJE, STIMULIRAJUĆI FAKTORI
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Polish |
Czynnik stymulujący komórki produkujące histaminę, CSF-GM, Czynnik stymulujący kolonie granulocyt-makrofag, CSF-2, TC-GM-CSF |
Italian |
Fattore stimolante le colonie dei granulociti e dei macrofagi
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