II. Characteristics
- Forms in Bone Marrow from Myeloblasts as with other Granulocytes (Basophils, Neutrophils, Monocytes)
- Function: Response to Allergy and Parasitic Infection
- Responds to mast cell, Basophil chemotactic factors
- Morphology on Blood Smear
- Granulocyte stains brightly with Eosin Stain
III. Interpretation: Normal
- Range: 1-4%
IV. Causes: Increased (Eosinophilia)
- Allergy
- Dermatologic Disorders
- Parasitic or Tropical infection
- Trichinosis
- Aspergillosis
- Hydatidosis
- Angiostrongylus
- Ascaris lumbricoides
- Capillariasis
- Cysticercosis
- Echinococcus
- Fascioliasis
- Filariasis
- Gnathostomiasis
- Paragonimiasis
- Schistosomiasis
- Strongyloidiasis
- Toxocara
- Trichuris trichiura
- Bacterial Infection
- Myeloproliferative disorders and other Malignancies
- Collagen-vascular diseases
- Medications
- Miscellaneous
- Eosinophilic Gastroenteritis
- Sarcoidosis
- Addison's Disease
- Loffler's Syndrome
V. Evaluation: Eosinophilia (Eosinophils >500/mm3)
- See Leukocytosis
- History and potential causes
- Travel history
- New medications
- Diagnostics (consider)
- Dermatitis biopsy (if present)
- Consider allergy and immunology Consultation or testing
- Consider Parasite testing (e.g. stool Ova and Parasites)
VI. References
- Saiki in Friedman (1991) Medical Diagnosis, p. 227
- Abramson (2000) Am Fam Physician 62(9):2053-60 [PubMed]
- Riley (2015) Am Fam Physician 92(11):1004-11 [PubMed]
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Related Studies (from Trip Database) Open in New Window
| Definition (MSH) | Abnormal increase of EOSINOPHILS in the blood, tissues or organs. |
| Definition (CSP) | disordered formation of eosinophils or an abnormal accumulation or deficiency of these cells. |
| Concepts | Disease or Syndrome (T047) |
| MSH | D004802 |
| ICD9 | 288.3 |
| ICD10 | D72.1 |
| SnomedCT | 418928000, 191363000, 165524009, 27955006 |
| English | Eosinophilia, Eosinophilias, EOSINOPHILIA, Eosinophilia NOS, eosinophilic leukocytosis (diagnosis), eosinophilia, eosinophilia (diagnosis), eosinophilic leukocytosis, Eosinophilia [Disease/Finding], eosinophilias, increased eosinophils, eosinophils increased, high eosinophil count, Eosinophilic leucocytosis, Eosinophilia (disorder), Eosinophilia NOS (disorder), Eosinophilia, NOS, Eosinophilia (disorder) [Ambiguous], Eosinophilic leukocytosis |
| French | EOSINOPHILIE, Eosinophilie, Éosinophilie |
| Spanish | EOSINOFILIA, leucocitosis eosinófila, leucocitosis con eosinofilia, eosinofilia, SAI (trastorno), eosinofilia, eosinofilia (hallazgo), recuento elevado de eosinófilos, eosinofilia, SAI, eosinofilia (trastorno), eosinofilia (concepto no activo), Eosinofilia |
| German | EOSINOPHILIE, Eosinophilie |
| Swedish | Eosinofili |
| Japanese | ｺｳｻﾝｷｭｳｿﾞｳｶｼｮｳ, 好酸球増加症, エオシン好性細胞増加症, 好酸球増加症-熱帯性, 熱帯性好酸球増加症, 好酸球増加, 好酸球性白血球増多症, 好酸球増多, 好酸球増多症 |
| Czech | eozinofilie, Eozinofilie |
| Finnish | Eosinofilia |
| Russian | EOZINOFILIIA, ЭОЗИНОФИЛИЯ |
| Portuguese | EOSINIFILIA, Eosinofilia |
| Korean | 호산구증다증 |
| Croatian | EOZINOFILIJA |
| Polish | Eozynofilia |
| Hungarian | eosinophilia |
| Norwegian | Eosinofili |
| Dutch | eosinofilie, Eosinofilie |
| Italian | Eosinofilia |
Ontology: eosinophil (C0014467)
| Definition (MSHCZE) | Eozinofilní granulocyt. Druh bílé krvinky (leukocyt) svýznamem v obraně proti parazitům a při alergii. Při těchto stavech je množství e. v krvi zvýšeno – eozinofilie. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ ) |
| Definition (NCI_NCI-GLOSS) | A type of immune cell that has granules (small particles) with enzymes that are released during infections, allergic reactions, and asthma. An eosinophil is a type of white blood cell and a type of granulocyte. |
| Definition (NCI) | Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin. |
| Definition (MSH) | Granular leukocytes with a nucleus that usually has two lobes connected by a slender thread of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and stainable by eosin. |
| Definition (CSP) | granular leukocyte readily stained by eosin; granules are coarse, round, and uniform in size; the nucleus usually has two lobes connected by a slender thread of chromatin; these cells are thought to play a specialized role in immunity to helminth infections. |
| Concepts | Cell (T025) |
| MSH | D004804 |
| SnomedCT | 14793004 |
| HL7 | EOS |
| LNC | LP28567-3, LP14539-8, MTHU009211, LA12895-1 |
| English | Eosinophils, Eosinophil, segmented, eosinocyte, acidophilic leukocyte, eosinophilic granulocyte, eosinophilic leukocyte, Eosinophil leukocyte, Eosinophil leucocyte, Blood eosinophils, eosinophils, blood eosinophils, Eosinophil, Eosinophil, segmented (cell), Blood Eosinophil, eosinophil |
| Spanish | eosinófilo, segmentado, Eosinófilos en sangre, eosinófilo, segmentado (célula), eosinófilo, Eosinófilos |
| Dutch | bloed eosinofielen, eosinofielen, Eosinofyl, Eosinofylen |
| French | Eosinophiles, Eosinophiles sanguins, Granulocytes éosinophiles, Granulocyte éosinophile, Éosinophiles, Polynucléaire éosinophile, Polynucléaires éosinophiles, PNE (Polynucléaire éosinophile), Granulocyte acidophile |
| German | Eosinophile im Blut, Eosinophile Granulozyten, Eosinophile Leukozyten, Eosinophile |
| Italian | Esinofili ematici, Eosinofili |
| Portuguese | Eosinófilos no sangue, Eosinófilos |
| Japanese | 好酸球, 血中好酸球, ｹｯﾁｭｳｺｳｻﾝｷｭｳ, ｺｳｻﾝｷｭｳ |
| Swedish | Eosinofila leukocyter |
| Czech | granulocyty eozinofilní, eozinofily, Eozinofily v krvi, Eozinofily |
| Finnish | Eosinofiilit |
| Russian | EOZINOFILY, LEIKOTSITY EOZINOFIL'NYE, ЛЕЙКОЦИТЫ ЭОЗИНОФИЛЬНЫЕ, ЭОЗИНОФИЛЫ |
| Croatian | EOZINOFILI |
| Latvian | Eozinofili |
| Polish | Granulocyty eozynofilne, Granulocyty kwasochłonne, Komórki kwasochłonne krwi, Eozynofile |
| Hungarian | Eozinofil vérszint, Eozinofilek |
| Norwegian | Leukocytter, eosinofile, Granulocytter, eosinofile, Eosinofile granulocytter, Eosinofile leukocytter, Eosinofile celler |
Ontology: Eosinophil count procedure (C0200638)
| Definition (NCI_CDISC) | A measurement of the eosinophils in a biological specimen. |
| Definition (NCI) | The determination of the number of eosinophils in a blood sample. |
| Concepts | Laboratory Procedure (T059) |
| SnomedCT | 165525005, 71960002, 365601007 |
| Italian | Conta eosinofila |
| Japanese | 好酸球数, ｺｳｻﾝｷｭｳｽｳ |
| English | Eosinophil Count, blood eosinophil count (lab test), blood eosinophil count, eosinophil count, Eosinophil count procedure, counts eosinophil, eosinophil count test, count eosinophil, Eosinophil count NOS, Eosinophil count NOS (procedure), Eosinophils, EOS, Eosinophil count, Eosinophil count (procedure), Eosinophil count - observation |
| Czech | Počet eozinofilů |
| Hungarian | Eozinofil szám |
| Spanish | recuento de eosinófilos, SAI, recuento de eosinófilos, SAI (procedimiento), recuento de eosinófilos (procedimiento), recuento de eosinófilos, Recuento de eosinófilos |
| Portuguese | Número de eosinófilos |
| Dutch | eosinofielentelling |
| French | Eosinophiles |
| German | Eosinophilenzahl |
