II. Pathophysiology

  1. Pulmonary or systemic infection of Aspergillus fungi
  2. Occurs in debilitated or Immunocompromised patients

III. Predisposing factors

  1. Chronic illness
  2. Long term use of antibiotics or Corticosteroids
  3. Irradiation

IV. Symptoms

  1. Pulmonary
    1. Dyspnea
    2. Cough
    3. Hemoptysis
  2. Systemic
    1. Skin eruption
    2. Arthralgias
    3. Mental status change

V. Signs

  1. Pulmonary
    1. Fever
    2. Purulent Sputum
  2. Systemic or Disseminated Infection
    1. Skin eruption
    2. Infection of ears, eyes, sinuses

VI. Lab

VII. Radiology: Chest XRay

  1. Pulmonary aspergilloma
    1. Unique crescentic radiolucency
    2. Surrounds a circular shadow

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