II. Pathophysiology
- Pulmonary or systemic infection of Aspergillus fungi
- Occurs in debilitated or Immunocompromised patients
III. Predisposing factors
- Chronic illness
- Long term use of Antibiotics or Corticosteroids
- Irradiation
IV. Symptoms
- Pulmonary
- Systemic
- Skin eruption
- Arthralgias
- Mental status change
V. Signs
- Pulmonary
- Systemic or Disseminated Infection
- Skin eruption
- Infection of ears, eyes, sinuses
VI. Lab
VII. Radiology: Chest XRay
- Pulmonary aspergilloma
- Unique crescentic radiolucency
- Surrounds a circular shadow
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Definition (MEDLINEPLUS) |
Aspergillosis is a disease caused by a fungus (or mold) called Aspergillus. The fungus is very common in both indoors and outdoors. Most people breathe in the spores of the fungus every day without being affected. But some people get the disease. It usually occurs in people with lung diseases or weakened immune systems. There are different kinds of aspergillosis. One kind is allergic bronchopulmonary aspergillosis (also called ABPA). Symptoms of ABPA include wheezing and coughing. ABPA can affect healthy people but it is most common in people with asthma or cystic fibrosis. Another kind is invasive aspergillosis, which damages tissues in the body. It usually affects the lungs. Sometimes it can also cause infection in other organs and spread throughout the body. It affects people who have immune system problems, such as people who have had a transplant, are taking high doses of steroids, or getting chemotherapy for some cancers. Your doctor might do a variety of tests to make the diagnosis, including a chest x-ray, CT scan of the lungs, and an examination of tissues for signs of the fungus. Treatment is with antifungal drugs. If you have ABPA, you may also take steroids. Centers for Disease Control and Prevention |
Definition (NCI_NCI-GLOSS) | An infectious fungal disease that occurs most often in the skin, ears, nasal sinuses, and lungs of people with suppressed immune systems. |
Definition (MSH) | Infections with fungi of the genus ASPERGILLUS. |
Definition (CSP) | disease condition caused by species of Aspergillus and marked by inflammatory granulomatous lesions in the skin, ear, orbit, nasal sinuses, lungs, and sometimes in the bones and meninges. |
Concepts | Disease or Syndrome (T047) |
MSH | D001228 |
ICD9 | 117.3 |
ICD10 | B44 , B44.9 |
SnomedCT | 266218008, 187492008, 154408001, 187087004, 65553006 |
English | Aspergilloses, Aspergillosis, unspecified, [X]Aspergillosis, unspecified, aspergillosis (diagnosis), aspergillosis, Aspergillosis [Disease/Finding], aspergillose, aspergilloses, Aspergillosis, [X]Aspergillosis, unspecified (disorder), Aspergillosis NOS, Infection due to Aspergillus, Aspergillosis (disorder), Aspergillosis, NOS |
Swedish | Aspergillos |
Czech | aspergilóza, Aspergilóza NOS, Aspergilóza |
Finnish | Aspergilloosi |
Russian | ASPERGILLEZ, АСПЕРГИЛЛЕЗ |
German | Aspergillose, nicht naeher bezeichnet, Aspergillose NNB, Aspergillose |
Korean | 상세불명의 아스페르길루스증, 아스페르길루스증 |
Croatian | ASPERGILOZA |
Polish | Aspergiloza, Kropidlakowica, Zakażenie Aspergillus |
Norwegian | Aspergillose |
Spanish | [X]aspergilosis, no especificada (trastorno), [X]aspergilosis, no especificada, Aspergilosis NEOM, aspergilosis (trastorno), aspergilosis, infección por Aspergillus, Aspergilosis |
Dutch | aspergillose, aspergillose NAO, Aspergillose, niet gespecificeerd, Aspergillose |
French | Aspergillose SAI, Aspergillose |
Hungarian | aspergillosis, aspergillosis k.m.n. |
Italian | Aspergillosi NAS, Aspergillosi |
Japanese | アスペルギルスショウNOS, アスペルギルスショウ, アスペルギルス症, アスペルギルス症NOS |
Portuguese | Aspergilose NE, Aspergilose |
Ontology: Aspergillus (C0004034)
Definition (NCI) | A genus of highly aerobic fungi in the phylum Ascomycota that grow as molds on the surface of a substrate. |
Definition (NCI_NCI-GLOSS) | Fungi commonly found in soil. Certain types of Aspergillus may cause disease, especially in people who have suppressed immune systems. |
Definition (MSH) | A genus of mitosporic fungi containing about 100 species and eleven different teleomorphs in the family Trichocomaceae. |
Definition (CSP) | genus of mitosporic fungi. |
Concepts | Fungus (T004) |
MSH | D001230 |
SnomedCT | 2429008 |
LNC | LP19998-1 |
English | Aspergillus, ASPERGILLUS, aspergillus, aspergillus fungus, Aspergillus (organism), Aspergillus, NOS |
Swedish | Mögelsvamp |
Czech | Aspergillus |
Finnish | Aspergillus |
Russian | ASPERGILL, ASPERGILLY, АСПЕРГИЛЛ, АСПЕРГИЛЛЫ |
Croatian | Not Translated[Aspergillus] |
Polish | Aspergillus, Kropidlaki |
Norwegian | Aspergillus, Strålemugg |
Spanish | Aspergillus (organismo), Aspergillus |
French | Aspergillus |
German | Aspergillus |
Italian | Aspergillus |
Dutch | Aspergillus |
Portuguese | Aspergillus |