II. Epidemiology
- Fungal Pericarditis is rare
III. Causes: Immunocompetent Patients
-
Histoplasmosis
- Most common Fungal Pericarditis cause in immunocompetent patients
- Mild cases may be treated as inflammatory Pericarditis (WITHOUT Antifungals)
- Blastomycosis
- Coccidioidomycosis
IV. Causes: Immunocompromised Patients
V. Risk Factors
- Immunocompromised
- Parenteral nutrition
- Prolonged Antibiotics
- Prolonged Corticosteroids
- Malignancy
VI. Findings
- See Pericarditis
- Toxic appearance (typically due to associated mediastinitis)
VII. Labs
- See Pericarditis
VIII. Differential Diagnosis
IX. Diagnosis
- Pericardiocentesis with fungal stains
X. Management
- See Pericarditis
- Consult infectious disease
- Intravenous Antifungals (e.g. Fluconazole, Amphotericin B)
XI. References
- Klasek and Alblaihed (2023) Crit Dec Emerg Med 37(6): 4-11