II. Background

  1. Aspergillus fumigatus colonization of airways and mucus

III. Risk Factors

IV. Components

  1. Bronchial Asthma
    1. Due to IgE mediated Hypersensitivity
  2. Bronchiectasis
    1. Due to immune complex deposition in proximal airways

V. Diagnosis

VI. Labs

  1. Peripheral Eosinophilia
  2. Serum precipitans to a. fumigatus
  3. Serum IgE increased

VII. Diagnostic Tests: Allergy Testing

  1. Immediate wheal and flare reaction to a. fumigatus

VIII. Management

  1. Long-term use of Systemic Corticosteroids

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Ontology: Aspergillosis, Allergic Bronchopulmonary (C0004031)

Definition (MSH) Hypersensitivity reaction (ALLERGIC REACTION) to fungus ASPERGILLUS in an individual with long-standing BRONCHIAL ASTHMA. It is characterized by pulmonary infiltrates, EOSINOPHILIA, elevated serum IMMUNOGLOBULIN E, and skin reactivity to Aspergillus antigen.
Definition (NCI) An immune reaction to aspergillus in patients usually suffering from asthma or cystic fibrosis.
Concepts Disease or Syndrome (T047)
MSH D001229
ICD9 518.6
ICD10 B44.81
SnomedCT 37981002
English Allergic Aspergilloses, Bronchopulmonary, Allergic Aspergillosis, Bronchopulmonary, Allergic Bronchopulmonary Aspergilloses, Allergic Bronchopulmonary Aspergillosis, Aspergilloses, Allergic Bronchopulmonary, Aspergilloses, Bronchopulmonary Allergic, Aspergillosis, Bronchopulmonary Allergic, Bronchopulmonary Allergic Aspergilloses, Bronchopulmonary Allergic Aspergillosis, Bronchopulmonary Aspergilloses, Allergic, Bronchopulmonary Aspergillosis, Allergic, ABPA - Allerg br-pul aspergill, Allerg bron-pul aspergillosis, Aspergillosis, Allergic Bronchopulmonary, ASPERG ALLERGIC BRONCHOPULM, ALLERGIC BRONCHOPULM ASPERG, BRONCHOPULM ASPERG ALLERGIC, ASPERG BRONCHOPULM ALLERGIC, allergic bronchopulmonary aspergillosis (diagnosis), allergic bronchopulmonary aspergillosis, ABPA, Bronchopulmonary aspergillosis allergic, Alrgc brncpul asprglosis, Aspergillosis, Allergic Bronchopulmonary [Disease/Finding], allergic bronchopulmonary aspergillosis (ABPA), abpa, allergic lung reaction to the fungus aspergillus, Allergic bronchopulmonary aspergillosis, ABPA - Allergic bronchopulmonary aspergillosis, Allergic bronchopulmonary aspergillosis (disorder)
Italian Aspergillosi broncopolmonare allergica, Aspergillosi allergica broncopolmonare
Dutch allergische bronchopulmonaire aspergillose, bronchopulmonaire aspergillosisallergie, Allergische bronchopulmonale aspergillose, Aspergillose, allergische bronchopulmonale, Bronchopulmonale aspergillose, Bronchopulmonale aspergillose, allergische
French Aspergillose broncho-pulmonaire allergique (ABPA), ABPA, Aspergillose bronchopulmonaire allergique, Aspergillose broncho-pulmonaire allergique
German ABPA, allergische bronchopulmonale Aspergillose, Allergische bronchopulmonale Aspergillose, Aspergillose, allergische bronchopulmonale, Bronchopulmonale Aspergillose
Spanish ABPA, aspergilosis broncopulmonar alérgica (trastorno), aspergilosis broncopulmonar alérgica, Aspergilosis broncopulmonar alérgica, Aspergilosis Broncopulmonar Alérgica
Swedish Aspergillos, allergisk bronkopulmonell
Japanese アレルギーセイキカンシハイアスペルギルスショウ, アスペルギルス症-アレルギー性気管支肺, アレルギー性気管支・肺アスペルギルス症, アレルギー性気管支肺アスペルギルス症, 気管支肺アスペルギルス症-アレルギー性, 気管支肺アスペルギルス症, アスペルギルス症-気管支肺
Czech aspergilóza alergická bronchopulmonální, Alergická bronchopulmonální aspergilóza, ABPA
Finnish Allerginen bronkopulmonaalinen aspergilloosi
Polish Aspergiloza alergiczna oskrzelowo-płucna
Hungarian ABPA, allergiás bronchopulmonalis aspergillosis, Allergiás bronchopulmonaris aspergillosis
Norwegian Allergisk bronkopulmonal aspergillose, Aspergillose, allergisk bronkopulmonal
Portuguese Aspergilose broncopulmonar alérgica, Aspergilose Broncopulmonar Alérgica