II. Epidemiology
- Affects immunocompetent children and young adults
- Higher Prevalence in warm, humid environments
- Accounts for 7% of Chronic Sinusitis requiring surgery
IV. Signs
- Nasal Polyps
- Chronic pansinusitis refractory to standard therapy
V. Labs: Sinus mucus examination
- Charcot Leyden crystals
- Non-invasive hyphae
- Numerous Eosinophils
VI. Radiology: Sinus XRay Findings
- Complete opacification of multiple sinuses
- Extension beyond sinus
- Wall erosion of involved sinus
- Scattered areas of high attenuation
- Mucosal thickening
VII. Differential Diagnosis
- Sinonasal neoplasm
- Fungal Sinusitis
- Bacterial Acute Sinusitis
VIII. Labs
- Total IgE elevated (often exceeds 1000)
IX. Management
- Surgical Debridement
- Immunotherapy with fungal and non-fungal Antigens
- Corticosteroids
- Irrigation and self-cleansing by patient