II. Definition

  1. Intraepidermal Acantholytic Blister
  2. Mnemonic: Pemphigus ends in S for Superficial
    1. Contrast with the deeper Pemphigoid

IV. Types: Secondary forms of Pemphigus

V. Signs

  1. Flaccid Blister (superficial)
  2. Nikolsky's Sign
    1. Positive in Pemphigus Vulgaris
    2. Negative in Pemphigus Foliaceus (most superficial)

VI. Histology

  1. All Pemphigus conditions show epidermal Acantholysis

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