Definition (CHV)
|
a chemical substance
|
Definition (CHV)
|
a chemical substance
|
Definition (NCI)
|
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. (NCI05)
|
Definition (NCI_NCI-GLOSS)
|
A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID).
|
Definition (MSH)
|
A nonsteroidal anti-inflammatory agent with analgesic properties used in the therapy of rheumatism and arthritis.
|
Definition (CSP)
|
nonsteroidal analgesic, antipyretic and anti-inflammatory agent that is a propionic acid derivative.
|
Definition (PDQ)
|
A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40475&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40475&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C561" NCI Thesaurus)
|
Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
MSH |
D007052
|
SnomedCT |
329955004, 329651005, 363606004, 322295006, 38268001, 387207008 |
LNC |
LP16165-0, MTHU004262, LA14347-1 |
English |
Ibuprofen, alpha-Methyl-4-(2-methylpropyl)benzeneacetic Acid, Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, Ibuprofen [cns analgesic], Ibuprofen [cns analgesic] [see j28..], Ibuprofen [musc-skel], Benzeneacetic Acid, Alpha-methyl-4-(2-methylpropyl)-, p-Isobutylhydratropic Acid, ibuprofen, Ibuprofen [musculoskeletal use], Ibuprofen product, ibuprofen (OTC), ibuprofen (medication), Ibuprofen PMR, Ibuprofen [musc-skel use 2], Ibuprofen [musculoskeletal use 2], non-prescription ibuprofen, non-prescription ibuprofen (medication), IBUPROFEN, Ibuprofen [Chemical/Ingredient], ibuprofen products, Ibuprofen product (substance), Ibuprofen [cns analgesic] [see j28..] (product), Ibuprofen [musculoskeletal use] (product), Ibuprofen [musculoskeletal use 2] (product), (.+ -.)-p-Isobutylhydratropic acid, Propionic acid-ibuprofen, p-Isobutylhydratropic acid, Ibuprofen (product), Ibuprofen (substance), Ibuprofen [cns analgesic] [see j28..] (substance), Ibuprofen [musculoskeletal use 2] (substance), Ibuprofen [musculoskeletal use] (substance) |
Swedish |
Ibuprofen
|
Czech |
ibuprofen
|
Finnish |
Ibuprofeeni
|
Russian |
IBUPROFEN, ИБУПРОФЕН |
Japanese |
イブプロフェン
|
Polish |
Ibuprofen, Brufen |
Norwegian |
Ibuprofen
|
Spanish |
ibuprofeno [uso musculoesquelético], ibuprofeno [uso musculoesquelético 2], ibuprofeno [analgésico de acción central] [véase j28..] (producto), ibuprofeno [analgésico de acción central] [véase j28..], ibuprofeno [uso musculoesquelético 2] (producto), ibuprofeno [uso musculoesquelético] (producto), ibuprofeno (producto), ibuprofeno (sustancia), ibuprofeno, ácido p-isobutilhidratrópico, Ibuprofeno |
French |
Ibuprofène
|
German |
Ibuprofen
|
Italian |
Ibuprofene
|
Portuguese |
Ibuprofeno
|