II. Epidemiology
-
Incidence: 313,000 Breast Augmentation procedures per year in U.S. (2018)
- Most Common U.S. cosmetic surgical procedure
III. Indications: Breast Implant
- Cosmetic Breast Augmentation
- Postmastectomy Breast Reconstruction
- Implants are more common than tissue implantation (e.g. TRAM Flap)
- Congenital Breast anomaly correction
- Breast hypoplasia
- Male to Female Transition Surgery ("Top" Surgery)
IV. Types: Implant
- Implant Fill Types
- Silicone
- Preferred by patients for its more natural feel
- Implant rupture risks leakage of silicone into the Breast parenchyma with associated complications
- FDA recommends MRI or Ultrasound at 5-6 years post-implant and then every 2-3 years
- Mean implant lifespan 4.9 years (removed for rupture, contracture, pain, malrotation, rippling)
- Saline
- Safely reabsorbed in case of rupture
- Mean implant lifespan 7.5 years (removed for rupture, contracture, pain, malrotation, rippling)
- Silicone
- Implant Size
- Volume ranges from 150 to 800 ml
- Implant Outer Shell Texture
- Smooth
- Risk of capsular contracture
- Textured
- Designed to reduce the risk of capsular contracture as seen with smooth implants
- Association with anaplastic large cell Lymphoma has resulted in discontinued textured implants in U.S.
- All textured implants recalled by manufacturer (Allergan) in 2019
- Smooth
V. Types: Procedure
- Incision Location
- Transaxillary
- Periareolar
- Increased risk of capsular contracture
- Inframammary
- Transumbilical
- Implant Pocket Location
- Prepectoral Implant
- Implanted superficial to the pectoralis major Muscle
- More comon in Breast Augmentation
- Less postoperative pain than submuscular Implant
- Risk of implant rippling visible below skin
- Submuscular Implant
- Implanted deep to the pectoralis major Muscle
- Preferred in Breast Augmentation after Mastectomy
- Implant is better covered by Muscle with less risk of infection, exposure
- Implant may displace (supralateral) with pectoralis Muscle Contraction (animation deformity)
- Implant rupture may be more difficult to detect than prepectoral implant
- Prepectoral Implant
VI. Management: Post-Operative
- Home Measures
- Displacement massage starting day 3 to 5 after surgery
- Return to Work
- Normal activities may be resumed at 1-2 weeks
- Avoid strenuous activity for 3-4 weeks
VII. Adverse Effects
-
Breast Cancer Screening Precautions
- Mammogram Test Sensitivity may be reduced with implants (despite the displacement views)
- Breast Implant rupture is uncommon with Mammogram, but may occur
-
Breast Feeding Precautions
- Breast Augmentation may significantly reduce ability to Breast feed
- Roberts (2015) Med J Aust 202(6): 324-8 [PubMed]
- Cheng (2018) J Hum Lact 34(3): 424-32 [PubMed]
- Bompy (2019) Ann Plast Surg 82(1): 11-4 [PubMed]
VIII. Complications: General
-
General
- Longterm complications typically occur within 8 years of implant
- Complications requiring repeat surgery in 24%
- Higher Incidence of complication post Mastectomy
- Lower complication Incidence with Breast enhancement
-
Breast Pain
- Shooting pain, burning and general discomfort is common following surgery
- Treat with Oral Analgesics (Acetaminophen, Ibuprofen)
- Bleeding or Hematoma (first 24 hours)
-
Wound Seroma
- Persistent fluid pocket at surgical site
- Drainage pf persistent seroma under Ultrasound by plastic surgery or by Intervention Radiology
- Implant rejection
- Presents with a sudden firmness at the implant
-
Chest Trauma to Breast Implant
- Evaluate for other chest injuries
- Breast Implant evaluation (confirming intact) is by non-emergent MRI
- Capsular contracture
- Scar tissue hardening around the Breast Implant
- Results in implant becoming palpable and visible, and in some cases distorted and painful
- Most common complication following Breast Implant (approximately 20% risk in 10 years)
- Higher risk with periareolar incision and with Breast Reconstruction
- Lower risk with textured implant outer shell (but not available due to risk of Lymphoma)
- Scar tissue hardening around the Breast Implant
- Deformity
- Implant asymmetry, malposition, rippling
- Implant may displace wih pectoralis Muscle Contraction (animation deformity) with submuscular placement
- Distorts Breast skin and nipple
- Silicone Breast Implant Illness
- No obvious consistent link between Rheumatologic Conditions and silicone implants
- Possible association with autoimmune Dysautonomia triggered by silicone in some cases
- Breast Implant Removal Indications
- Implant Rupture
- Capsular Contracture
- Silicone Breast Implant illness type symptoms
- Breast Implant associated ALCL
- Wound Infection (washout alone or with implant removal)
IX. Complications: Anaplastic large cell Lymphoma (Breast Implant associated ALCL, esp. textured implants)
- Presents as peri-implant effusion at 8-11 years after implant
- Rarely presents with Breast Mass, fever or Night Sweats
- Lymphoma that may originally appear similar to Cellulitis
- Axillary adenopathy in up to one third of patients
- As of 2020, FDA has issued a black box warning, and has found 733 cases of implant-associated ALCL
- Incidence: 1 in 30,000
- Most common with textured implants
- Evaluation
- Breast MRI (82% Test Sensitivity) or Breast Ultrasound (84% Test Sensitivity)
- Fine needle aspirate by surgery is diagnostic (CD30, cell morphology, T Cell Flow Cytometry)
- Management
- ALCL remains confined to Breast in most cases, and has a 90% five year survival
- Treatment with surgical excision and Chemotherapy
X. Complications: Implant Rupture
- Results in content leakage into surrounding tissue
- Requires routine surgical removal or replacement
- Mean time of rupture ~8 years from implant
- Saline implant rupture leaks into adjacent Breast tissue and is reabsorbed; decrease in Breast size obvious
- Silicone implants maintain their shape and size after rupture
- Silicone slowly extravasates into the surrounding capsule (intracapsular rupture)
- Silicone may extravasate further into the Breast parenchyma (extracapsular rupture)
- Interferes with mamography
- Silicone moves into regional Lymph Nodes
- Silicone Granulomas may form (may be confused with breast Nodules)
- FDA recommends MRI or Ultrasound at 5-6 years post-implant and then every 2-3 years
XI. Complications: Wound Infection
- Incidence 1 to 2.5%, typically presenting within the first 4 weeks after Breast Implant
- Risk Factors: Early Infection
- Diabetes Mellitus
- Tobacco Abuse
- Mastectomy skin-flap necrosis
- Lymph Node dissection
- Risk Factors: Late Infection (>30 days after implant)
- Reconstruction after Mastectomy
- Radiation Therapy
- Increased Body Mass Index
- Hematogenous risks of implant seeding
- Sepsis or bacteremia
- Dental work
- Chronic Foot Ulcer
- Signs
- Unilateral Breast Pain
- Warmth
- Swelling
- Erythema
- Erythema is normal (not infected) at incision site if <1-2 cm from incision
- Management
- Urgent Consultation with plastic surgery in all patients
- Antibiotics intravenous or oral depending on severity
- Breast Implant may need to be removed and the cavity washed out
- Implant salvage 58% in Breast Reconstruction cases
- Implant salvage 90% in Breast Augmentation with Antibiotics and possible surgical wash-out
- No implant replacement until after at least 6 months if removed
XII. References
- Claudius and LoTempio in Herbert (2018) EM:Rap 18(10): 17-8
- Gabriel (1997) N Engl J Med 336:677-82 [PubMed]
- Schrager (2021) Am Fam Physician 104(5): 500-8 [PubMed]