II. Epidemiology

  1. Most common of solid hematologic malignancies
  2. Incidence: 40,000 new cases/year in United States (19.7 per 100,000 persons)
  3. Prevalence: 509,065 in United States (2013)
  4. Median age of diagnosis: 67 years old (median age at death: 76 years old)
    1. Contrast with Hodgkin's Lymphoma with typically diagnosed between ages 20 to 34 years

III. Types: Common

  1. Non-Hodgkin B-Cell Lymphomas
    1. Diffuse Large B Cell Lymphoma
      1. Incidence: 7.2 per 100,000
      2. Median Age Onset: 60 to 70 years old
      3. Risk Factors include AIDS and immunomodulator medications (Biologic Agents)
      4. Five Year Survival: 63%
      5. Relapse rate: 40%
    2. Follicular Lymphoma
      1. Incidence: 3.5 per 100,000
      2. Five Year Survival: 88%
    3. Marginal Zone Lymphoma
      1. Incidence: 2.2 per 100,000
      2. Five Year Survival: 90%
    4. Precursor B Cell Lymphoma
      1. Incidence: 1.5 pcer 100,000
      2. Five Year Survival: 69%
    5. Burkitt Lymphoma
      1. Incidence: 0.4 per 100,000
      2. Five Year Survival: 64%
  2. Non-Hodgkin T Cell Lymphomas (and Natural Killer CellLymphomas)
    1. Peripheral T Cell Lymphoma
      1. Incidence: 1.2 per 100,000
      2. Five Year Survival: 58%
    2. Mycosis Fungoides (Cutaneous T-Cell Lymphoma)
      1. Incidence: 0.6 per 100,000
      2. Five Year Survival: 91%

IV. Risk Factors

  1. See Lymphoma (for risk factors common to all Lymphomas)
  2. Male
  3. White race
  4. Increasing age
  5. Family History
    1. Any first degree relative: 3.1 fold increased risk
    2. Increased risk is for the particular Lymphoma subtype, that the relative experienced
  6. Exposures
    1. Breast Implants
    2. Long-term Pesticide exposure

V. Findings: Symptoms and Signs (differentiate from Hodgkin's Lymphoma)

  1. Presence of Lymphadenopathy draining Waldeyer's ring
  2. Non-Hodgkin adenopathy occurs anywhere (contrast with supradiaphragmatic involvement in Hodgkin Lymphoma)
    1. Epitrochlear Lymph Nodes
    2. Mediastinal, abdominal and extranodal involvement
      1. Common at presentation
  3. Chest Pain (suggests lung involvement)
  4. Systemic symptoms are more common in Hodgkin's Lymphoma

VI. Diagnosis: Pathology (Lymph Node histology)

  1. See Lymphoma
  2. Diffuse small cleaved cell
  3. Poorly differentiated Lymphocytes
  4. Absence of Reed-Sternberg Cells (contrast with Hodgkin Lymphoma)

VII. Staging

  1. See Lymphoma

VIII. Management

  1. Combination Chemotherapy and Radiation Therapy
    1. Regimens vary depending on Non-Hodgkin Lymphoma subtype
  2. Chemotherapy: CHOP
    1. Cyclophosphamide
    2. Doxorubicin
    3. Vincristine
    4. Prednisone
  3. Adjunctive agents used with CHOP
    1. Rituximab (Rituxan, known as CHOP-R when used with CHOP protocol above)
      1. Rituximab is a Monoclonal Antibody that binds CD-20 Antigen on mature B Cells
    2. Bendamustine (Bendeka)
      1. Alkylating Agent
    3. Lenalidomide (Revlimid)
  4. Surveillance
    1. See Lymphoma for general surveillance protocols

IX. Complications

  1. See Lymphoma for complications shared by all Lymphomas
  2. Other cancers (related to primary cancer or its treatment)
    1. See Cancer Survivor Care
    2. Myelodysplasia
    3. Acute Leukemia
    4. Thyroid Cancer
    5. Head and neck cancer
    6. Breast Cancer
    7. Bladder Cancer
    8. Lung Cancer
    9. Skin Cancer
  3. Treatment related adverse effects
    1. Cardiomyopathy
    2. Thyroid disorders
    3. Sexual Dysfunction
  4. Paraneoplastic Syndromes (rare)
    1. Dermatomyositis
    2. Polymyositis

X. Prognosis: International Prognostic Index

  1. Background
    1. Varies by staging
    2. Overall five year survival: 69%
  2. Criteria
    1. Age >60 years
    2. Serum LDH Increased
    3. Eastern Cooperative Oncology Performance Status >=2
      1. Ambulatory but unable to carry out activities (or limited self care only or bedridden)
    4. Ann Arbor Stage III or IV Disease
      1. Multiple nodal groups on both sides of the diaphragm (may involve Spleen) OR
      2. Noncontiguous extranodal involvement
    5. Extranodal sites >1
  3. Interpretation
    1. Score 0-1: Five year survival 73%
    2. Score 2: Five year survival 51%
    3. Score 3: Five year survival 43%
    4. Score 4-5: Five year survival 26%
  4. References
    1. (1993) N Engl J Med 329(14):987-94 [PubMed]

XI. Prevention

  1. Vaccination
    1. See Lymphoma for common Vaccinations for both Hodgkin Lymphoma and Non-Hodgkin Lymphoma

XII. Resources

  1. Non-Hodgkin Lymphoma, CSR, 1975-2016 (NIH NCI)
    1. https://seer.cancer.gov/archive/csr/1975_2015/results_merged/sect_19_nhl.pdf
  2. Cancer Facts: Non-Hodgkin Lymphoma (NIH NCI)
    1. https://seer.cancer.gov/statfacts/html/nhl.html

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Related Studies

Ontology: Burkitt Lymphoma (C0006413)

Definition (NCI_NCI-GLOSS) An aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that occurs most often in children and young adults. The disease may affect the jaw, central nervous system, bowel, kidneys, ovaries, or other organs. There are three main types of Burkitt lymphoma (sporadic, endemic, and immunodeficiency related). Sporadic Burkitt lymphoma occurs throughout the world, and endemic Burkitt lymphoma occurs in Africa. Immunodeficiency-related Burkitt lymphoma is most often seen in AIDS patients.
Definition (NCI) The leukemic counterpart of Burkitt's lymphoma. The characteristic Burkitt cells are seen in the bone marrow and the peripheral blood. This is an aggressive leukemia.
Definition (NCI) A highly aggressive lymphoma composed of monomorphic medium-sized B-cells with basophilic cytoplasm and numerous mitotic figures. It is often associated with the presence of Epstein-Barr virus (EBV) and is commonly seen in AIDS patients. Three morphologic variants are recognized: classical Burkitt lymphoma, Burkitt lymphoma with plasmacytoid differentiation, and atypical Burkitt/Burkitt-like lymphoma. All cases express the MYC translocation [t(8;14)]. (WHO, 2001)
Definition (NCI_NCI-GLOSS) A rare, fast-growing type of leukemia (blood cancer) in which too many white blood cells called B lymphocytes form in the blood and bone marrow. It may start in the lymph nodes as Burkitt lymphoma and then spread to the blood and bone marrow, or it may start in the blood and bone marrow without involvement of the lymph nodes. Both Burkitt leukemia and Burkitt lymphoma have been linked to infection with the Epstein-Barr virus.
Definition (CSP) form of undifferentiated malignant lymphoma usually found in central Africa, but also reported in other parts of the world; commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass; B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma; the Epstein-Barr virus (human herpesvirus 4) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases, however, most non-African cases are EBV-negative.
Definition (MSH) A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
Concepts Neoplastic Process (T191)
MSH D002051
ICD9 200.2
ICD10 C83.7 , M9826/3, M9687/3, C83.70
SnomedCT 118617000, 77381001, 190023003, 188509006, 154581008, 188518008, 190022008, 22197008, 277571004, 397400006
English Burkitt Tumor, Burkitt's Lymphoma, Burkitt's Tumor, Burkitts Lymphoma, Burkitts Tumor, Lymphoma, Burkitt, Lymphoma, Burkitt's, Burkitt's tumor or lymphoma, Tumor, Burkitt's, Burk typ lymphom-smll noncleav, Burkitt's type lymphoma-undiff, Burkitt's lymph - unspec. site, Burkitt's lymphoma NOS, Burkitt's lymphoma of unspecified site, Burkitt's tumor NOS, Burkitt's tumor non-Hodgkin's lymphoma, Burkitt's tumors, Burkitt's tumour NOS, Burkitt's tumour non-Hodgkin's lymphoma, Burkitt's tumours, Tumor, Burkitt, [M]Burkitt's tumor NOS, [M]Burkitt's tumors, [M]Burkitt's tumour NOS, [M]Burkitt's tumours, BL, BURKITT LYMPHOMA, [M]Burkitt's tumor, [M]Burkitt's tumour, Burkitt Cell Leukemia, Leukemia, Burkitt Cell, Leukemia, Burkitt's, Burkitts Leukemia, Lymphocytic Leukemia, L3, Leukemias, L3 Lymphocytic, Burkitt Leukemia, Burkitt's Leukemia, Leukemia, Lymphocytic, L3, Leukemia, Lymphoblastic, Burkitt-Type, Leukemia, L3 Lymphocytic, Lymphocytic Leukemias, L3, Cell Leukemia, Burkitt, Leukemia, Burkitt, L3 Lymphocytic Leukemia, L3 Lymphocytic Leukemias, Burkitt's lymphoma, NOS, Burkitt cell leukemia (diagnosis), leukemia Burkitt cell, Burkitt's lymphoma (diagnosis), Burkitt lymphoma, unspecified site, Burkitt Lymphoma [Disease/Finding], burkitts tumor, burkitt lymphomas, burkitts lymphoma, burkitt's leukemia, b all, burkitt leukemia, burkitt tumor, burkitt's lymphoma, burkitt's non-hodgkin's lymphoma, burkitt's tumor, burkitt lymphoma, b-all, burkitts leukemia, Burkitt's lymphomas, [M]Burkitt's tumors (morphologic abnormality), [M]Burkitt's tumor NOS (morphologic abnormality), Burkitt's lymphoma NOS (disorder), Burkitt's lymphoma of unspecified site (disorder), Burkitt's tumour or lymphoma, Burkitt's lymphoma, Burkitt's tumor, Acute lymphoblastic leukemia, Burkitt's type, Burkitt's cell leukemia, Burkitt's tumour, Burkitt's type malignant lymphoma - undifferentiated, Malignant lymphoma, small noncleaved, Burkitt's, diffuse, Acute lymphoblastic leukaemia, Burkitt's type, Burkitt's cell leukaemia, B-cell acute lymphoblastic leukaemia, BL - Burkitt's lymphoma, Burkitt's type malignant lymphoma - small non-cleaved, Burkitt's leukaemia, Burkitt's leukemia, Burkitt cell leukaemia, Burkitt cell leukemia (morphologic abnormality), Burkitt cell leukemia, Burkitt lymphoma (morphologic abnormality), Burkitt lymphoma/leukaemia, Burkitt lymphoma/leukemia (morphologic abnormality), Burkitt lymphoma/leukemia, Burkitt lymphoma, Burkitt tumor [obs], Burkitt tumour [obs], Burkitt's lymphoma (clinical), Burkitt's lymphoma (disorder), Burkitt's lymphoma - disorder, Burkitt's tumor [obs], Burkitt's tumour [obs], FAB L3 [obs], Acute lymphoblastic leukaemia, mature B-cell type, Acute lymphoblastic leukemia, mature B-cell type, Malignant lymphoma, undifferentiated, Burkitt type [obs], NHL, Burkitt's, lymphoma, Burkitt's, non-Hodgkin's lymphoma, Burkitt's, cell leukemia; Burkitt, Burkitt; acute lymphoblastic leukemia (type), Burkitt; cell leukemia, Burkitt; lymphoma, Burkitt; tumor, lymphoma; Burkitt, lymphoma; undifferentiated cell, Burkitt's type, tumor; Burkitt, Malignant lymphoma, undifferentiated, Burkitt's type, Burkitt Lymphoma, FAB L3, L3 Acute Lymphoblastic Leukemia, L3 Acute Lymphocytic Leukemia, L3 Acute Lymphogenous Leukemia, L3 Acute Lymphoid Leukemia, Small Non-Cleaved Cell Lymphoma, Burkitt's Type, Burkitt's Cell Leukemia, Malignant lymphoma, Burkitt's type
Italian Linfomi di Burkitt, Linfoma o tumore di Burkitt, Linfoma di Burkitt NAS, Leucemia di Burkitt, Tumore di Burkitt, Linfoma di Burkitt
Dutch Burkitt-lymfoom NAO, Burkitts tumor, Burkitt-leukemie, burkitttumor of -lymfoom, Burkitt; acute lymfoblastenleukemie (type), Burkitt; cel-leukemie, Burkitt; lymfoom, Burkitt; tumor, cel-leukemie; Burkitt, lymfoom; Burkitt, lymfoom; ongedifferentieerd celtype, Burkitt-type, tumor; Burkitt, Burkitt-lymfomen, Afrikaans lymfoom, Burkitt-lymfoom, Burkitt-tumor, Lymfoom, Burkitt-
French Tumeur ou lymphome de Burkitt, Lymphome de Burkitt SAI, LLA-B, Leucémie de Burkitt, LAL-L3, Leucémie aiguë lymphoblastique de type Burkitt, Leucémie aigüe lymphoblastique B, Leucémie lymphoïde aiguë à cellules B, Leucémie aigüe lymphoblastique de type Burkitt, Leucémie lymphocytaire aigüe B, LAL-B, Leucémie lymphocytaire aiguë B, LAL3, LAL à cellules de Burkitt, Leucémie lymphoïde aigüe à cellules B, Lymphomes de Burkitt, Lymphome de Burkitt, Tumeur de Burkitt, Maladie de Burkitt
German Burkitt-Tumor oder -Lymphom, Burkitt Lymphom NNB, Burkitt-Leukaemie, B-Zell-Leukämie, akute, Akute B-Zell-lymphatische Leukämie, L3-lymphozytische Leukämie, B-ALL, Akute B-Zell-lymphozytische Leukämie, Burkitt Lymphome, Burkitt-Lymphom, Burkitt-Tumor, Lymphom, Burkitt-
Portuguese Tumor ou linfoma de Burkitt, Linfoma de Burkitt NE, Leucemia de Burkitt, Leucemia de Células de Burkitt, Linfoma-Leucemia de Burkitt, Linfomas de Burkitt, Linfoma de Burkitt, Tumor de Burkitt
Spanish Tumor o linfoma de Burkitt, Linfoma de Burkitt NEOM, Leucemia de Burkitt, Leucemia de Células de Burkitt, linfoma de Burkitt de localización no especificada, linfoma de Burkitt, SAI (trastorno), [M]tumores de Burkitt, [M]tumor de Burkitt, SAI (anomalía morfológica), linfoma de Burkitt, SAI, [M]tumores de Burkitt (anomalía morfológica), linfoma de Burkitt de localización no especificada (trastorno), [M]tumor de Burkitt, SAI, leucemia de Burkitt, leucemia de células de Burkitt (anomalía morfológica), leucemia de células de Burkitt, leucemia linfoblástica aguda, linfocitos B maduros, leucemia linfoblástica aguda, tipo Burkitt, leucemia/linfoma de Burkitt (anomalía morfológica), leucemia/linfoma de Burkitt, linfoma de Burkitt (anomalía morfológica), linfoma de Burkitt (trastorno), linfoma de Burkitt - trastorno, linfoma de Burkitt, linfoma maligno tipo Burkitt - de células pequeñas, no segmentadas, linfoma maligno tipo Burkitt - indiferenciado, linfoma maligno, células pequeñas no clivadas, de Burkitt, difuso, linfoma maligno, células pequeñas no hendidas, de Burkitt, difuso, linfoma maligno, indiferenciado, tipo Burkitt, linfoma tipo Burkitt, tumor de Burkitt, Linfomas de Burkitt, Linfoma de Burkitt, Tumor de Burkitt
Japanese バーキットリンパ腫NOS, バーキットリンパシュ, バーキットリンパシュNOS, バーキットハッケツビョウ, バーキットシュヨウ, アフリカ・リンパ腫, バーキット・リンパ腫, 白血病-バーキット, リンパ性白血病-B細胞性-急性, Burkitt白血病, 急性Bリンパ性白血病, 白血病-B細胞性急性リンパ性, 白血病-Burkitt, リンパ性白血病-L3, Burkittリンパ腫, 急性リンパ性白血病-B細胞性, 白血病-リンパ芽球性-Burkitt型, バーキット白血病, B細胞性急性リンパ性白血病, Bリンパ性白血病-急性, Burkitt型リンパ芽球性白血病, 白血病-リンパ性L3, 白血病-B細胞性-急性, 白血病-B細胞性-急性リンパ性, 白血病-急性B細胞性, 急性B細胞性リンパ性白血病, 急性Bリンパ球性白血病, L3リンパ性白血病, 白血病-急性リンパ性-B細胞性, B細胞性白血病-急性, 急性B細胞性白血病, 白血病-リンパ性-急性-B細胞性, リンパ性白血病-B細胞性急性, バーキット腫瘍あるいはリンパ腫, バーキットシュヨウアルイハリンパシュ, Burkitt腫瘍, アフリカリンパ腫, バーキットリンパ腫, バーキットリンパ腺腫, バーキット腫瘍, リンパ腫-バーキット, リンパ腫-Burkitt
Swedish Burkitts lymfom
Czech Burkittův lymfom, Burkittovy lymfomy, Burkittův lymfom NOS, Burkittův nádor, Burkittův nádor nebo lymfom, Burkittova leukémie
Finnish Burkittin lymfooma
Russian ЛЕЙКОЗ ЛИМФОБЛАСТНЫЙ L3, ЛЕЙКОЗ ЛИМФОБЛАСТНЫЙ ОСТРЫЙ B-КЛЕТОЧНЫЙ, LEIKOZ LIMFOBLASTNYI TIPA BERKITTA, ЛИМФОБЛАСТНАЯ АНЕМИЯ B-КЛЕТОЧНАЯ ОСТРАЯ, LIMFOBLASTNAIA ANEMIIA B-KLETOCHNAIA OSTRAIA, LEIKOZ LIMFOBLASTNYI L3, LIMFOMA AFRIKANSKAIA, LIMFOMA BERKITTA, BERKITTA LEIKOZ, LIMFOMA TSENTRAL'NO-AFRIKANSKAIA, БЕРКИТТА ЛЕЙКОЗ, BERKITTA LIMFOSARKOMA, BERKITTA LIMFOMA, AFRIKANSKAIA LIMFOMA, LEIKOZ LIMFOBLASTNYI OSTRYI B-KLETOCHNYI, ЛЕЙКОЗ ЛИМФОБЛАСТНЫЙ ТИПА БЕРКИТТА, ЛЕЙКОЗ B-КЛЕТОЧНЫЙ ОСТРЫЙ, LEIKOZ B-KLETOCHNYI OSTRYI, АФРИКАНСКАЯ ЛИМФОМА, БЕРКИТТА ЛИМФОМА, БЕРКИТТА ЛИМФОСАРКОМА, ЛИМФОМА АФРИКАНСКАЯ, ЛИМФОМА БЕРКИТТА, ЛИМФОМА ЦЕНТРАЛЬНО-АФРИКАНСКАЯ
Korean 버키트 종양
Croatian BURKITTOV LIMFOM
Polish Guz Burkitta, Chłoniak Burkitta, Białaczka B-komórkowa ostra, Białaczka Burkitta, Chłoniak afrykański, B-ALL
Hungarian Burkitt-tumor, Burkitt-leukemia, Burkitt-lymphoma, Burkitt-féle tumor, Burkitt-tumor vagy -lymphoma, Burkitt-lymphomák, Burkitt-leukaemia, Burkitt-lymphoma k.m.n.
Norwegian Burkitt lymfom, Burkitt tumor, Burkitt leukemi, Lymfatisk leukemi, L3

Ontology: Lymphoma, Follicular (C0024301)

Definition (NCI) A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
Definition (NCI_CDISC) A neoplasm of lymphoid cells which has at least a partial follicular pattern.
Definition (NCI_NCI-GLOSS) A type of B-cell non-Hodgkin lymphoma (cancer of the immune system) that is usually indolent (slow-growing). The tumor cells grow as groups to form nodules. There are several subtypes of follicular lymphoma.
Definition (MSH) Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the LYMPH NODES. The nodules resemble to some extent the GERMINAL CENTER of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-LYMPHOCYTES.
Concepts Neoplastic Process (T191)
MSH D008224
ICD9 202.0
ICD10 M9692/3 , C82, C82.9, M9690/3
SnomedCT 46324005, 308121000, 188607003, 188617008, 188681004, 189995005, 188608008, 189994009, 269510001, 55150002, 269476000, 307637005, 277618009
English Brill Symmers Disease, Brill-Symmers Disease, Follicular Lymphoma, Follicular Lymphoma, Giant, Follicular Lymphomas, Follicular Lymphomas, Giant, Giant Follicular Lymphoma, Giant Follicular Lymphomas, Lymphoma, Giant Follicular, Lymphoma, Nodular, Lymphomas, Follicular, Lymphomas, Giant Follicular, Lymphomas, Nodular, Nodular Lymphomas, Disease, Brill-Symmers, Nodular Lymphoma, M lyoma,centrbl-centrcyt,foll, Follicular [nodular] non-Hodgkin's lymphoma, Follicular non-Hodgkin's lymphoma, unspecified, Nodular lymphoma NOS, Nodular lymphoma of unspecified site, Nodular lymphoma-unspec. site, Lymphoma, Follicular, GIANT FOLLIC LYMPHOMA, FOLLIC LYMPHOMA, FOLLIC LYMPHOMA GIANT, LYMPHOMA FOLLIC, LYMPHOMA GIANT FOLLIC, BRILL SYMMERS DIS, Foll low grade B-cell lymphom, [M]Mal.lym,centr-blas/cyt,foll, Mal.lym,centr-blas/cyt,foll, [M]Malignant lymphoma, centroblastic-centrocytic, follicular, Follicular non-Hodgkin's lymph, [M]Malig.lymphoma, nodular NOS, [M]Malignant lymphoma, nodular NOS, Malig.lymphoma, nodular NOS, Malignant lymphoma, nodular NOS, nodular malignant lymphoma (diagnosis), nodular malignant lymphoma, giant follicular lymphosarcoma (diagnosis), nodular lymphoma, nodular lymphosarcoma, giant follicular lymphosarcoma, nodular lymphosarcoma (diagnosis), Nodular (follicular) lymphoma, Follicular non-Hodgkin lymphoma, Follicular lymphoma, unspecified, Lymphoma, Follicular [Disease/Finding], Malignant lymphoma, follicular NOS, lymphoma follicular, lymphosarcoma follicular, follicular lymphomas, giant follicular lymphoma, follicular lymphoma (diagnosis), follicular lymphoma, malignant neoplasm nodular lymphoma follicular, (Nodular lymphoma: Brill-Symmers disease) or (reticulosarcoma - follicular or nodular) (disorder), Nodular lymphoma NOS (disorder), Follicular lymphoma NOS, Follicular lymphoma: [non-Hodgkin's] or [NOS] (disorder), Nodular lymphoma (Brill - Symmers disease), (Nodular lymphoma: Brill-Symmers disease) or (reticulosarcoma - follicular or nodular), [M]Malignant lymphoma, centroblastic-centrocytic, follicular (morphologic abnormality), [M]Malignant lymphoma, nodular NOS (& [Brill - Symmers' disease]), [M]Follicular lymphosarcoma NOS, [M]Malignant lymphoma, nodular NOS (& [Brill - Symmers' disease]) (disorder), [M]Giant follicular lymphoma, [M]Brill - Symmers' disease, Follicular lymphoma: [non-Hodgkin's] or [NOS], Malignant lymphoma, centroblastic-centrocytic, follicular (morphologic abnormality), Nodular lymphoma of unspecified site (disorder), Reticulosarcoma - follicular or nodular, [M]Malignant lymphoma, nodular NOS (morphologic abnormality), [M]Nodular lymphosarcoma NOS, follicular malignant lymphoma - centroblastic-centrocytic, malignant neoplasm lymphoma follicular - centroblastic-centrocytic, malignant neoplasm lymphoma b-cell low grade follicular, follicular malignant lymphoma - centroblastic-centrocytic (diagnosis), Follicular low grade B-cell lymphoma (diagnosis), LYMPHOMA, FOLLICULAR CENTRE CELL, FOLLICULAR NON-HODGKIN LYMPHOMA, LYMPHOMA, FOLLICULAR, MALIGNANT, FOLLICULAR CENTRE CELL LYMPHOMA, FOLLICLE CENTER LYMPHOMA, FOLLICULAR NON-HODGKIN'S LYMPHOMA, Malignant lymphoma, nodular, Malignant lymphoma, follicular, Nodular lymphosarcoma, Follicular lymphosarcoma, Nodular lymphoma, Giant follicular lymphoma, Brill - Symmers' disease, Germinoblastoma, follicular, Malignant lymphoma, centroblastic-centrocytic, follicular, Nodular malignant lymphoma, Follicular low grade B-cell lymphoma, Follicular non-Hodgkin's lymphoma, Follicular lymphoma, Follicular low grade B-cell lymphoma (disorder), Follicular lymphoma (morphologic abnormality), Follicular non-Hodgkin's lymphoma (disorder), Malignant lymphoma, centroblastic-centrocytic, follicular (disorder), Malignant lymphoma, follicle center, follicular, Malignant lymphoma, follicle center, Malignant lymphoma, follicle centre, follicular, Malignant lymphoma, follicle centre, Malignant lymphoma, lymphocytic, nodular, Nodular lymphoma (disorder), follicular; germinoblastoma, follicular; lymphosarcoma, germinoblastoma; follicular, Brill-Symmers, lymphocytic; lymphoma, nodular, lymphoma; follicular, lymphoma; lymphocytic, nodular, lymphoma; nodular, lymphocytic, lymphoma; nodular, lymphosarcoma; follicular, nodular; lymphoma, lymphocytic, nodular; lymphoma, Malignant lymphoma, follicular, NOS, Malignant lymphoma, lymphocytic, nodular, NOS, Malignant lymphoma, nodular, NOS, Malignant lymphoma, centroblastic-centrocytic, follicular -RETIRED-, Follicle Center Lymphoma, Follicular Non-Hodgkin Lymphoma, Follicular Non-Hodgkin's Lymphoma, Brill-Symmers disease, Giant follicular lymphosarcoma, Nodular lymphocytic lymphoma
Dutch nodulair lymfoom, nodulair (folliculair) lymfoom, folliculair; germinoblastoom, folliculair; lymfosarcoom, germinoblastoom; folliculair, lymfocytair; lymfoom, nodulair, lymfoom; folliculair, lymfoom; lymfocytair, nodulair, lymfoom; nodulair, lymfocytair, lymfoom; nodulair, lymfosarcoom; folliculair, nodulair; lymfoom, lymfocytair, nodulair; lymfoom, Folliculair non-Hodgkin-lymfoom, niet gespecificeerd, Folliculair [nodulair] non-Hodgkin-lymfoom, Brill-Symmers-ziekte, Folliculair lymfoom, Folliculair reuzenlymfoom, Lymfoom, folliculair, Lymfoom, nodulair
French Lymphome nodulaire (folliculaire), Lymphome gigantofolliculaire, Lymphome folliculaire géant, Lymphome folliculaire, Lymphome nodulaire, Maladie de Brill-Symmers
German nodulaeres Lymphom, nodulaeres (follikulaeres) Lymphom, Follikulaeres Non-Hodgkin-Lymphom, nicht naeher bezeichnet, Follikulaeres [nodulaeres] Non-Hodgkin-Lymphom, Brill-Symmers-Syndrom, Follikuläres Lymphom, Lymphom, follikuläres, Lymphom, großfollikuläres, Lymphom, noduläres
Italian Linfoma nodulare (follicolare), Linfoma gigante follicolare, Malattia di Brill-Symmers, Linfoma nodulare, Linfoma follicolare
Portuguese Linfoma (folicular) nodular, Linfoma nodular, Doença de Brill-Symmers, Linfoma Folicular Gigante, Linfoma Folicular, Linfoma Nodular
Spanish Linfoma nodular, Linfoma nodular (folicular), [M]linfoma maligno, nodular, SAI, linfoma maligno, centroblástico - centrocítico, folicular (concepto no activo), [M] linfoma maligno, centroblástico-centrocítico, folicular, linfoma nodular, SAI (trastorno), linfoma nodular, SAI, [M] linfoma maligno, centroblástico-centrocítico, folicular (anomalía morfológica), [M]linfoma maligno, nodular, SAI (anomalía morfológica), linfoma nodular de localización no especificada (trastorno), linfoma nodular de localización no especificada, linfoma folicular (anomalía morfológica), linfoma folicular de células B de bajo grado (trastorno), linfoma folicular de células B de bajo grado, linfoma folicular, linfoma maligno, centroblástico - centrocítico, folicular, linfoma maligno, centroblástico centrocítico, folicular (trastorno), linfoma maligno, centroblástico centrocítico, folicular, linfoma maligno, centrofolicular, folicular, linfoma maligno, centrofolicular, linfoma maligno, folicular, linfoma maligno, linfocítico, nodular, linfoma maligno, nodular, linfoma no Hodgkin folicular (trastorno), linfoma no Hodgkin folicular, linfoma nodular (trastorno), linfoma nodular maligno, linfoma nodular, Enfermedad de Brill-Symmers, Linfoma Folicular Gigante, Linfoma Folicular, Linfoma Nodular
Japanese 結節性(濾胞性)リンパ腫, ケッセツセイロホウセイリンパシュ, ケッセツセイリンパシュ, Brill-Symmers病, 結節性混合大小細胞型リンパ腫, 結節性大リンパ様リンパ腫, 混合細胞性リンパ腫-結節性, 混合細胞リンパ腫-濾胞性, 混合大小細胞型結節性リンパ腫, 混合リンパ球組織球型結節性リンパ腫, 小細胞・大細胞混合性リンパ腫-結節性, リンパ腫-結節性-混合大小細胞型, リンパ腫-小型濾胞中心細胞型, リンパ腫-混合細胞型-濾胞性, リンパ腫-濾胞性小分割細胞性, 小細胞・大細胞混合性リンパ腫-濾胞性, 小非正円形細胞型リンパ腫-濾胞性, 大細胞型濾胞性リンパ腫, リンパ腫-結節性-大濾胞中心細胞, リンパ腫-結節性リンパ球・組織球混合性, リンパ腫-小割細胞-濾胞性, リンパ腫-組織球性-結節性, 濾胞性小リンパ様リンパ腫, 結節性小細胞・大細胞混合性リンパ腫, 結節性大濾胞中心細胞リンパ腫, 結節性リンパ球・組織球混合性リンパ腫, 混合細胞性リンパ腫-濾胞性, 大小非正円形細胞型濾胞性リンパ腫, リンパ腫-混合大小リンパ様-濾胞性, リンパ腫-大小非正円形細胞型-濾胞性, リンパ腫-大濾胞中心細胞-結節性, リンパ腫-濾胞性混合細胞, リンパ腫-濾胞性小細胞・大細胞混合性, リンパ腫-濾胞性リンパ球・組織球混合性, 濾胞性混合大小リンパ様リンパ腫, 濾胞性混合リンパ球組織球型リンパ腫, 結節性低分化リンパ球性リンパ腫, 混合細胞型濾胞性リンパ腫, 混合リンパ球組織球型濾胞性リンパ腫, 組織球性リンパ腫-結節性, 低分化結節性リンパ球性リンパ腫, リンパ腫-結節性-混合リンパ球組織球型, リンパ腫-混合細胞-濾胞性, リンパ腫-混合大小細胞型-結節性, リンパ腫-小リンパ様-濾胞性, リンパ腫-大リンパ様-結節性, リンパ腫-濾胞性混合細胞型, リンパ腫-濾胞性混合細胞性, リンパ腫-濾胞性大細胞, 濾胞性小非正円形細胞型リンパ腫, 小型濾胞中心細胞型リンパ腫, 大濾胞中心細胞結節性リンパ腫, リンパ球・組織球混合性リンパ腫-結節性, リンパ腫-結節性小細胞・大細胞混合性, リンパ腫-混合リンパ球組織球型-濾胞性, リンパ腫-リンパ球性-結節性-低分化, リンパ腫-濾胞性-混合大小リンパ様, 濾胞性小細胞・大細胞混合性リンパ腫, 濾胞性小分割細胞性リンパ腫, 組織球性結節性リンパ腫, リンパ球性リンパ腫-結節性-低分化, リンパ球・組織球混合性リンパ腫-濾胞性, リンパ腫-結節性組織球性, リンパ腫-濾胞性, 濾胞性小割細胞リンパ腫, 濾胞性リンパ球・組織球混合性リンパ腫, 結節性混合細胞性リンパ腫, 結節性混合リンパ球組織球型リンパ腫, 混合細胞型リンパ腫-濾胞性, 混合大小リンパ様濾胞性リンパ腫, 小割細胞リンパ腫-濾胞性, 小分割細胞性リンパ腫-濾胞性, リンパ腫-結節性-組織球性, リンパ腫-混合リンパ球組織球型-結節性, リンパ腫-小非正円形細胞型-濾胞性, リンパ腫-濾胞性小割細胞, リンパ腫-濾胞性小非正円形細胞型, 濾胞性混合細胞性リンパ腫, 濾胞性大小非正円形細胞型リンパ腫, 結節性組織球性リンパ腫, 大細胞リンパ腫-濾胞性, リンパ腫-結節性-大リンパ様, リンパ腫-結節性混合細胞性, リンパ腫-結節性リンパ球性-低分化, リンパ腫-大細胞-濾胞性, リンパ腫-濾胞性-混合リンパ球組織球型, リンパ腫-濾胞性-大小非正円形細胞型, 濾胞性混合細胞リンパ腫, 濾胞性大細胞リンパ腫, ろ胞性リンパ腫, リンパ腫-巨大濾胞性, リンパ芽細胞腫-濾胞性, 巨大濾胞性リンパ腫, 濾胞性リンパ腫, 結節性リンパ腫, リンパ腫-結節性, 巨大ろ胞性リンパ腫, 濾胞性リンパ芽細胞腫
Swedish Lymfom, follikulärt
Finnish Follikulaarinen lymfooma
Russian LIMFOMA FOLLIKULIARNAIA, LIMFOMA SMESHANNOKLETOCHNAIA FOLLIKULIARNAIA, ЛИМФОЦИТАРНАЯ ЛИМФОМА УЗЛОВАЯ ПЛОХО ДИФФЕРЕНЦИРОВАННАЯ, ЛИМФОМА КРУПНОКЛЕТОЧНАЯ ФОЛЛИКУЛЯРНАЯ, LIMFOMA MELKOFOLLIKULIARNAIA TSENTROTSITARNAIA, ЛИМФОМА УЗЛОВАЯ КРУПНОФОЛЛИКУЛЯРНАЯ ЦЕНТРОКЛЕТОЧНАЯ, ЛИМФОМА КРУПНОЛИМФОИДНАЯ УЗЛОВАЯ, LIMFOMA UZLOVAIA SMESHANNAIA LIMFOTSITARNO-GISTIOTSITARNAIA, ГИСТИОЦИТАРНАЯ ЛИМФОМА УЗЛОВАЯ, GISTIOTSITARNAIA LIMFOMA UZLOVAIA, ЛИМФОМА МЕЛКОДРОБЛЕНОКЛЕТОЧНАЯ ФОЛЛИКУЛЯРНАЯ, LIMFOMA MELKODROBLENOKLETOCHNAIA FOLLIKULIARNAIA, ЛИМФОМА МЕЛКОФОЛЛИКУЛЯРНАЯ ЦЕНТРОЦИТАРНАЯ, LIMFOMA UZLOVAIA KRUPNOFOLLIKULIARNAIA TSENTROKLETOCHNAIA, ЛИМФОМА ФОЛЛИКУЛЯРНАЯ МЕЛКОДРОБЛЕНОКЛЕТОЧНАЯ И КРУПНОДРОБЛЕНОКЛЕТОЧНАЯ, LIMFOTSITARNAIA LIMFOMA UZLOVAIA PLOKHO DIFFERENTSIROVANNAIA, LIMFOMA NODULIARNAIA, LIMFOBLASTOMA FOLLIKULIARNAIA, LIMFOMA FOLLIKULIARNAIA MELKODROBLENOKLETOCHNAIA I KRUPNODROBLENOKLETOCHNAIA, LIMFOMA KRUPNOLIMFOIDNAIA UZLOVAIA, ЛИМФОМА МЕЛКОЛИМФОИДНАЯ ФОЛЛИКУЛЯРНАЯ, LIMFORETIKULEZ, BRILLA-SIMMERSA BOLEZN', LIMFOMA GIGANTOFOLLIKULIARNAIA, ЛИМФОМА УЗЛОВАЯ СМЕШАННАЯ ЛИМФОЦИТАРНО-ГИСТИОЦИТАРНАЯ, LIMFOMA KRUPNOKLETOCHNAIA FOLLIKULIARNAIA, LIMFOMA MELKOLIMFOIDNAIA FOLLIKULIARNAIA, ЛИМФОМА СМЕШАННОКЛЕТОЧНАЯ ФОЛЛИКУЛЯРНАЯ, БРИЛЛА-СИММЕРСА БОЛЕЗНЬ, ЛИМФОБЛАСТОМА ФОЛЛИКУЛЯРНАЯ, ЛИМФОМА ГИГАНТОФОЛЛИКУЛЯРНАЯ, ЛИМФОМА НОДУЛЯРНАЯ, ЛИМФОМА ФОЛЛИКУЛЯРНАЯ, ЛИМФОРЕТИКУЛЕЗ
Czech Nodulární (folikulární) lymfom, Nodulární lymfom, lymfom z obrovských folikulů, Brillova-Symmersova choroba, lymfom folikulární, Brillova-Symmersova nemoc, folikulární lymfom
Korean 여포성[결절성] 비호지킨 림프종, 상세불명의 여포성 비호지킨 림프종
Polish Chłoniak grudkowy, Chłoniak wielogrudkowy, Choroba Brilla-Symmersa, Chłoniak folikularny, Chłoniak olbrzymiogrudkowy
Croatian LIMFOM, FOLIKULARNI, NODOZNI LIMFOM, NODULARNI LIMFOM, FOLIKULARNI LIMFOM
Hungarian Nodularis (tüszős) lymphoma, Nodularis lymphoma
Norwegian Follikulært lymfom

Ontology: Lymphoma, Non-Hodgkin (C0024305)

Definition (NCI) Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage.
Definition (NCI_NCI-GLOSS) Any of a large group of cancers of lymphocytes (white blood cells). NHLs can occur at any age and are often marked by lymph nodes that are larger than normal, fever, and weight loss. There are many different types of NHL. These types can be divided into aggressive (fast-growing) and indolent (slow-growing) types, and they can be formed from either B-cells or T-cells. B-cell NHLs include Burkitt lymphoma, chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), diffuse large B-cell lymphoma, follicular lymphoma, immunoblastic large cell lymphoma, precursor B-lymphoblastic lymphoma, and mantle cell lymphoma. T-cell NHLs include mycosis fungoides, anaplastic large cell lymphoma, and precursor T-lymphoblastic lymphoma. Lymphomas that occur after bone marrow or stem cell transplantation are usually B-cell NHLs. Prognosis and treatment depend on the stage and type of disease.
Definition (MSH) Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease.
Definition (CSP) characterized by malignant lymphomas; clinically similar to Hodgkin's disease, except that the lymphomas seen in this disease are initially more widespread; most common manifestation is painless enlargement of one or more peripheral lymph nodes.
Concepts Neoplastic Process (T191)
MSH D008228
ICD10 M9672/3 , C85.9, C83.1, M9591/3
SnomedCT 118601006, 1929004, 128929007, 63086004, 271385002, 190168009, 154583006, 134176000, 269628007, 188675007
English Lymphoma, Non Hodgkin's, Lymphoma, Non-Hodgkin's, Lymphoma, Non-Hodgkins, Lymphoma, Nonhodgkin, Lymphoma, Nonhodgkin's, Lymphoma, Nonhodgkins, Non Hodgkin's Lymphoma, Non-Hodgkin Lymphoma, Non-Hodgkin's Lymphoma, Non-Hodgkins Lymphoma, Nonhodgkin's Lymphoma, nonHodgkin's lymphoma, Dif non-H sm clv cel (dif) lya, Malignant lymphoma, small cleaved cell, diffuse, Non-Hod lympha, unspec type, Non-Hodgkin's lymphoma, unspecified type, [X]Non-Hod lympha, unspec type, [X]Non-Hodgkin's lymphoma, unspecified type, Lymphoma, Non Hodgkin, Lymphoma, Non Hodgkins, MALIGNANT LYMPHOMA NON HODGKINS TYPE, Non Hodgkin Lymphoma, Nonhodgkins Lymphoma, Small cleaved cell (diffuse), Small cleaved cell (diffuse) non-Hodgkin's lymphoma, NON-HODGKIN LYMPHOMA, LYMPHOMA, NON-HODGKIN, FAMILIAL, NHL, NON-HODGKIN'S LYMPHOMA, NONHODGKIN LYMPHOMA, [M]Malignant lymphoma, small cleaved cell, diffuse, [M]Malg lymph,smal cleav,difus, Malg lymph,smal cleav,difus, [M]Mal lymphoma, non-Hodg type, Mal lymphoma, non-Hodg type, [M]Malignant lymphoma, non-Hodgkin's type, [M]Non-Hodgkin's lymphoma, Malig lymphoma, non-Hodgkin's, Non-Hodgkin's lymphoma NOS, Diffuse Small Cleaved-Cell Lymphoma, Diffuse Small Cleaved Cell Lymphoma, Lymphoma, Small Cleaved Cell, Diffuse, LYMPHOMA SMALL CLEAVED DIFFUSE, Small Cleaved Cell Lymphoma, Diffuse, Lymphoma, Atypical Diffuse Small Lymphoid, DIFFUSE SMALL CLEAVED LYMPHOMA, Lymphoma, Small Cleaved-Cell, Diffuse, Small Cleaved-Cell Lymphoma, Diffuse, SMALL CLEAVED LYMPHOMA DIFFUSE, Malignant lymphoma, non-Hodgkin's, NOS, non-Hodgkin's lymphoma, non-Hodgkin's lymphoma (diagnosis), Non-Hodgkin lymphoma - category, Non-Hodgkin lymphoma, no ICD-O subtype, Lymphoma, Non-Hodgkin, Non-Hodgkin lymphoma, Non-Hodgkin's Lymphoma (NHL), Non-Hodgkin lymphoma NOS, Lymphoma, Non-Hodgkin [Disease/Finding], Malignant lymphoma, non-Hodgkin's NOS, non hodgkin lymphoma, non hodgkin's lymphoma (NHL), non-hodgkins lymphoma, Lymphoma;non Hodgkins, non hodgkin's lymphoma, nonhodgkin lymphoma, nhl, non-hodgkin's lymphoma, nonhodgkin's lymphoma, nonhodgkins lymphoma, non-hodgkin lymphoma, Lymphoma, Non-Hodgkin, Familial, [X]Non-Hodgkin's lymphoma, unspecified type (disorder), [M]Malignant lymphoma, small cleaved cell, diffuse (morphologic abnormality), Lymphoma (non-Hodgkin's), Non-Hodgkin lymphoma, no International Classification of Diseases for Oncology subtype (morphologic abnormality), Non-Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality), Non-Hodgkin lymphoma, no International Classification of Diseases for Oncology subtype, NHL, NOS, Non-Hodgkin lymphoma, NOS, non-Hodgkin lymphoma, Diffuse non-Hodgkin's small cleaved cell (diffuse) lymphoma, Malignant lymphoma, non-Hodgkin's type, Non-Hodgkin's lymphoma, NHL - Non-Hodgkin's lymphoma, Malignant lymphoma, cleaved cell [obs], Malignant lymphoma, non-Hodgkin's, Malignant lymphoma, non-Hodgkin, Malignant lymphoma, small cell, noncleaved, diffuse [obs], Malignant lymphoma, small cleaved cell [obs], Malignant lymphoma, small cleaved cell, diffuse [obs], Malignant lymphoma, undifferentiated cell type [obs], Malignant lymphoma, undifferentiated cell, non-Burkitt [obs], Non-Hodgkin lymphoma (category), Non-Hodgkin lymphoma - category (morphologic abnormality), Non-Hodgkin's lymphoma (clinical), Non-Hodgkin's lymphoma (disorder), Non-Hodgkin's lymphoma - disorder, lymphoma, non-Hodgkin's, diffuse; lymphoma, small cell, cleaved, lymphoma; diffuse, small cell, cleaved, lymphoma; non-Hodgkin's, lymphoma; small cell, cleaved (diffuse), non-Hodgkin's; lymphoma, small cell; lymphoma, cleaved (diffuse), Non-Hodgkin's lymphoma, NOS, Malignant lymphoma, small cleaved cell, diffuse -RETIRED-, Non-Hodgkin`s lymphoma, Non-Hodgkins lymphoma, non hodgkins lymphoma
French LYMPHOME NON HODGKINIEN, Lymphome non hodgkinien SAI, Lymphome (non hodgkinien), LMNH, Lymphome non hodgkinien, Lymphome malin non hodgkinien
Portuguese LINFOMA NAO HODGKIN, Linfoma não-Hodgkin NE, Linfoma (não Hodgkin), Linfoma não Hodgkiniano, Linfoma não de Hodgkin, Linfoma não Hodgkin
Spanish linfoma no hodgkiniano (categoría, anomalía morfológica), morfología: linfoma maligno no hodgkiniano, no clasificado como subtipo en CIE - O, Linfoma (no Hodgkin), Linfoma no hodgkiniano NEOM, Linfoma no Hodgkiniano, linfoma no hodgkiniano (trastorno), linfoma no-Hodgkin (trastorno), [M] linfoma maligno, de células pequeñas clivadas, difuso, [X]linfoma no Hodgkin, tipo no especificado, [M] linfoma maligno, de células pequeñas clivadas, difuso (anomalía morfológica), linfoma no hodgkiniano, [X]linfoma no Hodgkin, tipo no especificado (trastorno), linfoma maligno, de células pequeñas hendidas, difuso (concepto no activo), linfoma maligno, de células pequeñas hendidas, difuso, linfoma no-Hodgkin, (M)linfoma, no hodgkiniano, linfoma ahodgkiniano, linfoma maligno, no hodgkiniano, linfoma maligno, tipo no hodgkiniano, linfoma no hodgkiniano (categoría), linfoma no hodgkiniano (categoría, anomalía morfológica) (anomalía morfológica), linfoma, no hodgkiniano, morfología: linfoma maligno no hodgkiniano, no clasificado como subtipo en CIE - O (anomalía morfológica), Linfoma no hodgkiniano, (M)linfoma maligno tipo no Hodgkin, Linfoma no Hodgkin
Dutch non-Hodgkin-lymfoom NAO, lymfoom (non-Hodgkin), diffuus; lymfoom, kleincellig, gekerfd, kleincellig; lymfoom, gekerfd (diffuus), lymfoom; diffuus, kleincellig, gekerfd, lymfoom; kleincellig, gekerfd (diffuus), lymfoom; non-Hodgkin, non-Hodgkin; lymfoom, Non-Hodgkin-lymfoom, kleine gekerfde cellen (diffuus), Non-Hodgkin-lymfoom, niet gespecificeerd type, non-Hodgkin-lymfoom, Lymfoom, non-Hodgkin-, Non-Hodgkin-lymfoom
German Lymphom (Non-Hodgkin), Non-Hodgkin-Lymphom NNB, Lymphom, kleinzelliges gekerbtkerniges, diffuses, NON-HODGKIN LYMPHOM, Non-Hodgkin-Lymphom, Typ nicht naeher bezeichnet, Non-Hodgkin-Lymphom: Kleinzellig, gekerbt (diffus), Lymphom, Non-Hodgkin-, Non-Hodgkin-Lymphom
Italian Linfoma (non-Hodgkin), Limfoma diffuso a piccole cellule indentate, Linfoma diffuso a piccoli linfociti atipici, Linfoma non-Hodgkin NAS, Linfoma non-Hodgkin
Japanese 非ホジキンリンパ腫NOS, リンパ腫(非ホジキン), ヒホジキンリンパシュNOS, ヒホジキンリンパシュ, リンパシュヒホジキン, 軽度リンパ腫, 混合リンパ性組織球性リンパ腫, 小非分割型細胞性リンパ腫, びまん性小分割細胞性リンパ腫, びまん性リンパ腫, リンパ球・組織球混合性リンパ腫-びまん性, リンパ腫-軽度, リンパ腫-混合大小細胞型-びまん性, リンパ腫-びまん性混合細胞性, リンパ腫-びまん性リンパ球・組織球混合性, 混合細胞性リンパ腫-びまん性, 混合細胞リンパ腫-汎発性, 混合リンパ球組織球型びまん性リンパ腫, 小細胞・大細胞混合性リンパ腫-びまん性, 汎発性小割細胞リンパ腫, 非分割小細胞リンパ腫, びまん性混合大小細胞型リンパ腫, びまん性混合リンパ球組織球型リンパ腫, リンパ腫-混合リンパ球組織球型-びまん性, リンパ腫-小割細胞-汎発性, リンパ腫-汎発性, リンパ腫-びまん性-混合リンパ球組織球型, リンパ腫-びまん性-大小非正円形細胞型, リンパ腫-びまん性混合細胞型, 肉腫-リンパ, びまん性混合細胞性リンパ腫, リンパ腫-混合細胞-汎発性, リンパ腫-小細胞-非分割, リンパ腫-多形性, リンパ腫-汎発性混合細胞, リンパ腫-汎発性小割細胞, 混合細胞型リンパ腫-びまん性, 混合細胞性リンパ腫, 混合リンパ球組織球型リンパ腫, びまん性混合細胞リンパ腫, び慢性リンパ腫, リンパ腫-びまん性, リンパ腫-びまん性-混合大小細胞型, リンパ腫-びまん性小分割細胞性, リンパ肉腫, 異型びまん性小リンパ様リンパ腫, 細網肉腫, 小割細胞リンパ腫-汎発性, 小非正円形細胞型リンパ腫-びまん性, 小分割細胞性リンパ腫-びまん性, びまん性小細胞・大細胞混合性リンパ腫, リンパ腫-高度, リンパ腫-小型非切れ込み核細胞, リンパ腫-混合リンパ球組織球型, リンパ腫-混合リンパ性組織球性, リンパ腫-小非分割細胞性, リンパ腫-びまん性小細胞・大細胞混合性, リンパ腫-びまん性未分化, 高度リンパ腫, 小型円形細胞型リンパ腫, 小型非切れ込み核細胞リンパ腫, 混合リンパ腫, 多形性リンパ腫, びまん性大小非正円形細胞型リンパ腫, リンパ腫-瀰漫性, リンパ腫-びまん性小非正円形細胞型, リンパ腫-未分化-びまん性, リンパ腫-リンパ球・組織球混合性, 小非分割細胞性リンパ腫, 中等度リンパ腫, 汎発性混合細胞リンパ腫, 汎発性リンパ腫, びまん性混合細胞型リンパ腫, びまん性小非正円形細胞型リンパ腫, びまん性未分化リンパ腫, 瀰漫性リンパ腫, 未分化リンパ腫, リンパ球・組織球混合性リンパ腫, リンパ腫-異型びまん性小リンパ様, リンパ腫-小型円形細胞型, リンパ腫-混合, リンパ腫-小非分割型細胞性, リンパ腫-小リンパ様-異型びまん性, リンパ腫-中等度, リンパ腫-非Hodgkin, リンパ腫-非分割小細胞, Non-Hodgkinリンパ腫, 細網細胞肉腫, びまん性リンパ球・組織球混合性リンパ腫, 未分化リンパ腫-びまん性, リンパ腫-混合細胞-びまん性, リンパ腫-混合細胞性, リンパ腫-小非正円形細胞型-びまん性, リンパ腫-大小非正円形細胞型-びまん性, リンパ腫-未分化, リンパ腫-非ホジキン, 非Hodgkinリンパ腫, 非ホジキンリンパ腫, 非ホジキン悪性リンパ腫, リンパ腫-Non-Hodgkin, 悪性リンパ腫-非ホジキン
Swedish Non-Hodgkins lymfom
Czech lymfom nehodgkinský, Nehodkinský lymfom NOS, Nehodgkinský lymfom, Lymfom (nehodgkinský), non-Hodgkinův lymfom, nehodgkinský lymfom, nehodgkinské lymfomy, lymfom non-Hodgkinův
Finnish Non-Hodgkin-lymfooma
Russian ЛИМФОМА МЕЛКОДРОБЛЕНОКЛЕТОЧНАЯ ДИФФУЗНАЯ, LIMFOMA MELKODROBLENOKLETOCHNAIA DIFFUZNAIA, LIMFOMA SMESHANNAIA LIMFOTSITARNO-GISTIOTSITARNAIA, ЛИМФОМА СМЕШАННОКЛЕТОЧНАЯ, ЛИМФОМА, ПОЗДНЯЯ СТАДИЯ, LIMFOMA, PROMEZHUTOCHNAIA STADIIA, LIMFOMA NE-KHODZHKINA, LIMFOMA DIFFUZNAIA, LIMFOMA NEDIFFERENTSIROVANNAIA DIFFUZNAIA, ЛИМФОМА НИЗКОЙ СТЕПЕНИ ДИФФЕРЕНЦИРОВАННАЯ, LIMFOMA SMESHANNAIA, ЛИМФОМА СМЕШАННАЯ ЛИМФОЦИТАРНО-ГИСТИОЦИТАРНАЯ, LIMFOMA SMESHANNOKLETOCHNAIA, LIMFOMA, NACHAL'NAIA STADIIA, ЛИМФАТИЧЕСКАЯ САРКОМА, LIMFATICHESKAIA SARKOMA, ЛИМФОМА АТИПИЧНАЯ ДИФФУЗНАЯ МЕЛКОЛИМФОИДНОКЛЕТОЧНАЯ, ЛИМФОМА МЕЛКОКЛЕТОЧНАЯ С НЕРАСЩЕПЛЕННЫМ ЯДРОМ, LIMFOMA PO STADIIAM RAZVITIIA, ЛИМФОМА СМЕШАННОКЛЕТОЧНАЯ ДИФФУЗНАЯ, LIMFOMA MELKOKLETOCHNAIA S NERASSHCHEPLENNYM IADROM, ЛИМФОМА НЕДИФФЕРЕНЦИРОВАННАЯ, ЛИМФОМА НЕДИФФЕРЕНЦИРОВАННАЯ ДИФФУЗНАЯ, LIMFOMA SMESHANNOKLETOCHNAIA DIFFUZNAIA, ЛИМФОМА, НАЧАЛЬНАЯ СТАДИЯ, LIMFOSARKOMA, LIMFOMA NIZKOI STEPENI DIFFERENTSIROVANNAIA, ЛИМФОМА СМЕШАННАЯ, ЛИМФОСАРКОМА, LIMFOMA ATIPICHNAIA DIFFUZNAIA MELKOLIMFOIDNOKLETOCHNAIA, ЛИМФОМА ДИФФУЗНАЯ, LIMFOMA NEDIFFERENTSIROVANNAIA, LIMFOMA, POZDNIAIA STADIIA, ЛИМФОМА, ПРОМЕЖУТОЧНАЯ СТАДИЯ, ЛИМФОМА НЕ-ХОДЖКИНА, ЛИМФОМА ПО СТАДИЯМ РАЗВИТИЯ
Korean 상세불명 형의 비호지킨림프종, 소분할세포(미만성)비호지킨 림프종
Croatian LIMFOM, NON-HODGKIN
Polish Chłoniak rozlany, Chłoniak o średniej złośliwości, Chłoniak nieziarniczy, Mięsak limfatyczny, Chłoniak o niskiej złośliwości, Chłoniak z małych komórek, Chłoniak nie-Hodgkina, Chłoniak o wysokiej złośliwości, Chłoniak z komórek mieszanych
Hungarian Non-Hodgkin-lymphoma k.m.n., Lymphoma (non-Hodgkin), Non-Hodgkin-lymphoma
Norwegian Non-Hodgkins lymfom

Ontology: B-Cell Lymphomas (C0079731)

Definition (NCI_NCI-GLOSS) A type of cancer that forms in B cells (a type of immune system cell). B-cell lymphomas usually occur in adults and may be either indolent (slow-growing) or aggressive (fast-growing). There are many different types of B-cell lymphomas, and prognosis and treatment depend on the type and stage of cancer.
Definition (NCI) The most common type of non-Hodgkin lymphoma. It includes the most frequently seen morphologic variants which are: diffuse large B-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma and marginal zone B-cell lymphoma. -- 2003
Definition (MSH) A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes.
Definition (CSP) any in a large group of nonHodgkin's lymphoma's characterized by malignant transformation of the B lymphocytes.
Concepts Neoplastic Process (T191)
MSH D016393
SnomedCT 109979007, 1929004, 413616009
English B Cell Lymphoma, B-Cell Lymphoma, Lymphoma, B Cell, Lymphoma, B-Cell, Lymphomas, B-Cell, B cell lymphoma, B-Cell Non-Hodgkin's Lymphoma, Lymphomas Non-Hodgkin's B-Cell, Non-Hodgkin's Lymphoma B-Cell, B-Cell Non-Hodgkin Lymphoma, B-Cell Non Hodgkin's Lymphoma, B-cell lymphoma NOS, Lymphoma, B-Cell [Disease/Finding], b cells lymphomas, b cell lymphomas, b-cell lymphomas, b cell lymphoma, b cells lymphoma, cell b lymphoma, b-cell lymphoma, lymphoma b-cell, b cell lymphoma non hodgkin's, lymphoma b cell, lymphomas non-hodgkin's b-cell, Lymphomas non-Hodgkin's B-cell, B-cell lymphoma (diagnosis), malignant neoplasm lymphoma b-cell, B-cell lymphoma, B-cell lymphoma (clinical), B-cell lymphoma (disorder), B-cell lymphoma, no ICD-O subtype, B-cell; lymphoma, lymphoma; B-cell, B-cell lymphoma, no ICD-O subtype (morphologic abnormality), Non-Hodgkin's B-Cell Lymphoma, B-Cell Lymphocytic Neoplasm, B-Cell Neoplasm, B-Cell Lymphomas, B-cell neoplasm (morphologic abnormality), B-cell neoplasm
Spanish linfoma de linfocitos B, Linfoma de células B NEOM, linfoma de células B, linfoma de linfocitos B (clínico), linfoma de linfocitos B (trastorno), Linfoma de células B, Linfomas no hodgkinianos de células B, neoplasia de células B, neoplasia de linfocitos B (anomalía morfológica), neoplasia de linfocitos B, Linfoma de Células B
Italian Linfomi non-Hodgkin a cellule B, Linfoma a cellule B NAS, Linfoma a cellule B
Dutch B-cellymfoom NAO, B-cel; lymfoom, lymfoom; B-cel, non-Hodgkin B-cel lymfomen, B-cellymfoom, Lymfoom, B-cel-
French Lymphome B SAI, Lymphomes non hodgkiniens à cellules B, Lymphome B, Lymphome à cellules B
German B-Zell-Lymphom NNB, Non-Hodgkin-B-Zell-Lymphome, B-Zell-Lymphom, Lymphom, B-Zell-
Portuguese Linfoma de células B NE, Linfoma dos linfócitos B, Linfoma não-Hodgkin de células B, Linfoma de Células B
Japanese B細胞性リンパ腫NOS, B細胞性リンパ腫, 非ホジキンB細胞性リンパ腫, ヒホジキンBサイボウセイリンパシュ, Bサイボウセイリンパシュ, BサイボウセイリンパシュNOS, B細胞性リンパ腫, リンパ腫-B細胞性, B細胞リンパ腫
Swedish B-cellslymfom
Czech lymfom z B-lymfocytů, lymfom B-buněčný, B-buněčný lymfom, B-buněčný lymfom NOS, Non-Hodgkinské B-lymfomy
Finnish B-solulymfooma
Russian LIMFOMA B-KLETOCHNAIA, B-KLETOCHNAIA LIMFOMA, B-КЛЕТОЧНАЯ ЛИМФОМА, ЛИМФОМА B-КЛЕТОЧНАЯ
Polish Chłoniak B-komórkowy, Chłoniak z komórek B
Hungarian Lymphomás nem-Hodgkin B-sejt, B-sejtes lymphoma k.m.n., B-sejtes lymphoma
Norwegian B-cellelymfom
Croatian LIMFOM B-STANICA

Ontology: Diffuse Large B-Cell Lymphoma (C0079744)

Definition (NCI_NCI-GLOSS) A type of B-cell non-Hodgkin lymphoma (cancer of the immune system) that is usually aggressive (fast-growing). It is the most common type of non-Hodgkin lymphoma, and is marked by rapidly growing tumors in the lymph nodes, spleen, liver, bone marrow, or other organs. Other symptoms include fever, night sweats, and weight loss. There are several subtypes of diffuse large B-cell lymphoma.
Definition (NCI) A non-Hodgkin lymphoma characterized by a diffuse proliferation of predominantly large neoplastic B lymphocytes. It is the most frequently seen type of non-Hodgkin lymphoma, representing 30%-40% of the cases. Morphologic variants include centroblastic lymphoma, immunoblastic lymphoma, and anaplastic lymphoma. Subtypes/entities include T-cell/histiocyte rich large B-cell lymphoma, primary diffuse large B-cell lymphoma of the central nervous system, plasmablastic lymphoma, primary cutaneous diffuse large B-cell lymphoma, leg type, and ALK-positive large B-cell lymphoma.
Definition (MSH) Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.
Concepts Neoplastic Process (T191)
MSH D016403
ICD10 C83.3 , M9680/3
SnomedCT 109969005, 46732000
English Diffuse Histiocytic Lymphoma, Diffuse Histiocytic Lymphomas, Diffuse Large Cell Lymphoma, Diffuse Large-Cell Lymphoma, Diffuse Large-Cell Lymphomas, Histiocytic Lymphoma, Diffuse, Histiocytic Lymphomas, Diffuse, Large Cell Lymphoma, Diffuse, Large Lymphoid Lymphoma, Diffuse, Large-Cell Lymphoma, Diffuse, Large-Cell Lymphomas, Diffuse, Lymphoma, Diffuse Histiocytic, Lymphoma, Diffuse Large Cell, Lymphoma, Diffuse Large-Cell, Lymphoma, Histiocytic, Diffuse, Lymphoma, Large Cell, Diffuse, Lymphomas, Diffuse Histiocytic, Lymphomas, Diffuse Large-Cell, Diff malig lymphoma-histiocyt, Diff malig lymphoma-large cell, Mal lymphom-large cleav+non cl, Large cell (diffuse), Large cell (diffuse) non-Hodgkin's lymphoma, Malig lymph,large cell,diff, Malignant lymphoma, large cell, diffuse NOS, [M]Malig lymph,large cell,diff, [M]Malignant lymphoma, large cell, diffuse NOS, LYMPHOMA DIFFUSE LARGE, DIFFUSE LARGE LYMPHOMA, LYMPHOMA LARGE DIFFUSE, LARGE LYMPHOMA DIFFUSE, Diffuse, Large B-Cell, Lymphoma, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Large-Cell, Diffuse, Histiocytic Lymphomas, Lymphomas, Histiocytic, Lymphoma, Large Lymphoid, Diffuse, Histiocytic Lymphoma, Lymphoma, Histiocytic, Diffuse non-Hodgkin's lymphoma, large cell, Diffuse Large B-Cell Lymphoma, DHL, diffuse histiocytic malignant lymphoma (DHL), DHL (diffuse histiocytic lymphoma), diffuse histiocytic malignant lymphoma (DHL) (diagnosis), Malignant lymphoma, large B-cell, diffuse, no ICD-O subtype, diffuse histiocytic lymphoma (DHL), Diffuse large B-cell lymphoma NOS, Diffuse non-Hodgkin lymphoma, large cell, Lymphoma, Large B-Cell, Diffuse [Disease/Finding], diffuse large b-cell lymphoma, diffuse large cell lymphoma, large cell diffuse lymphoma, diffuse histiocytic lymphoma, diffuse large b cell lymphoma, Diffuse large B-cell lymphomas, Malignant lymphoma, large B-cell, diffuse, no International Classification of Diseases for Oncology subtype (morphologic abnormality), Malignant lymphoma, large B-cell, diffuse, no International Classification of Diseases for Oncology subtype, Malignant lymphoma, large B-cell, diffuse, no ICD-O subtype (morphologic abnormality), diffuse large B-cell lymphoma, Malignant lymphoma, histiocytic, Malignant lymphoma, histiocytic, diffuse, Diffuse malignant lymphoma - histiocytic, Diffuse malignant lymphoma - large cell, Malignant lymphoma, large cell, cleaved and noncleaved, Malignant lymphoma - large cell cleaved and non-cleaved, Diffuse large B-cell lymphoma, Diffuse non-Hodgkin's lymphoma, large cell (clinical), Diffuse non-Hodgkin's lymphoma, large cell (disorder), Malignant lymphoma, large B-cell, diffuse, Malignant lymphoma, large B-cell, Malignant lymphoma, large cell, diffuse [obs], Malignant lymphoma, large cell, diffuse; lymphoma, histiocytic, diffuse; lymphoma, large cell, lymphoma; diffuse, histiocytic, lymphoma; diffuse, large cell, lymphoma; large cell (diffuse), Malignant lymphoma, histiocytic, NOS, Malignant lymphoma, large cell, NOS, Malignant lymphoma, large cell, diffuse, NOS, DLBCL, Malignant lymphoma, large B-cell, diffuse (morphologic abnormality)
Spanish linfoma no hodgkiniano difuso, de células grandes, Linfoma difuso de células B grandes NEOM, linfoma maligno, linfocitos B grandes, difuso (anomalía morfológica), Linfoma Difuso de Células B Grandes, Linfoma de Células B Grandes Difuso, linfoma maligno, linfocitos B grandes, difuso, linfoma maligno, linfocitos B grandes, difuso, subtipo no ICD-O (anomalía morfológica), linfoma maligno, linfocitos B grandes, difuso, subtipo no ICD-O, linfoma maligno, linfocitos B grandes, difuso, no clasificado como subtipo en CIE-O, linfoma maligno, linfocitos B grandes, difuso, no clasificado como subtipo en CIE-O (anomalía morfológica), linfoma maligno - de células grandes segmentadas y no segmentadas, linfoma maligno de linfocitos B grandes difuso, linfoma maligno difuso - histiocítico, linfoma maligno, células grandes, clivadas y no clivadas, linfoma maligno, células grandes, hendidas y no hendidas, linfoma maligno, células grandes, segmentadas y no segmentadas, linfoma maligno, de células grandes, linfoma maligno, histiocítico, difuso, linfoma maligno, histiocítico, linfoma maligno, linfocitos B grandes, linfoma no Hodgkin difuso, de células grandes (clínico), linfoma no hodgkiniano difuso, de células grandes (clínico), linfoma no hodgkiniano difuso, de células grandes (trastorno), Linfoma difuso de células B grandes, Linfomas difusos de células B grandes, Linfoma Histiocítico Difuso
Italian Linfomi diffusi a grandi cellule B, Linfoma diffuso a grandi cellule B, non specificato, Linfoma diffuso a grandi cellule B, Linfoma a grandi cellule, Linfoma diffuso a grandi cellule, Linfoma diffuso a grandi cellule linfoidi, Linfoma istocitico, Linfoma istocitico diffuso
Dutch grootcellig B-cellymfoom diffuus NAO, diffuus; lymfoom, grootcellig, diffuus; lymfoom, histiocytair, lymfoom; diffuus, grootcellig, lymfoom; diffuus, histiocytair, lymfoom; grootcellig (diffuus), Non-Hodgkin-lymfoom, grootcellig (diffuus), diffuse grootcellige B-cellymfomen, diffuus grootcellig B-cellymfoom, Diffuus lymfoom, grootcellig, Grootcellig diffuus lymfoom, Histiocytair lymfoom, diffuus, Lymfoom, grootcellig diffuus, Lymfoom, grootcellig diffuus ongedifferentieerd, Lymfoom, histiocytair diffuus
French Lymphome diffus à grandes cellules B SAI, Lymphome histiocytaire, Lymphome diffus à grandes cellules, Lymphome diffus à grandes cellules B, Lymphome à grandes cellules, Lymphome B diffus à grandes cellules, Lymphomes malins diffus à grandes cellules B, Lymphome malin diffus à grandes cellules B, Lymphome histiocytaire diffus, Lymphome diffus centrofolliculaire, Lymphome diffus indifférencié à grandes cellules, Lymphome diffus à grandes cellules centro-folliculaires, Lymphome diffus à grandes cellules lymphoïdes
German diffuses grosszelliges B-Zell-Lymphom NNB, Diffuses großzelliges B-Zell-Lymphom, Großzelligs B-Zell-Lymphom, Großzelliges Lymphom, Lymphom, großzelliges, diffuses, B-Zell-, Diffuses großzelliges Lymphom, Non-Hodgkin-Lymphom: Grosszellig (diffus), Diffuse grosszellige B-Zell-Lymphome, diffuses grosszelliges B-Zell-Lymphom, Histiozytäres Lymphom, diffuses, Lymphom, großlymphozytäres, diffuses, Lymphom, großzelliges, diffuses, undifferenziertes, Lymphom, histiozytäres, diffuses
Portuguese Linfoma difuso de grandes células B NE, Linfoma Difuso de Células Grandes B, Linfoma Difuso de Grandes Células B, Linfoma de Células Grandes B Difuso, Linfoma de Células Grandes Tipo B Difuso, Linfoma difuso de grandes células B, Linfoma maligno difuso com grandes células B, Linfoma Histiocítico Difuso
Japanese びまん性大細胞型B細胞性リンパ腫NOS, びまん性大細胞型B細胞性リンパ腫, ビマンセイダイサイボウガタBサイボウセイリンパシュ, ビマンセイダイサイボウガタBサイボウセイリンパシュNOS, 組織球性リンパ腫, びまん性大細胞型B細胞性リンパ腫, リンパ腫-B細胞性-びまん性大細胞, リンパ腫-びまん性大細胞, Bリンパ腫-びまん性大細胞, びまん性大細胞型B細胞リンパ腫, リンパ腫-組織球性, び漫性大細胞型Bリンパ腫, びまん性大細胞Bリンパ腫, リンパ腫-びまん性大細胞型B細胞性, B細胞性リンパ腫-びまん性大細胞型, び漫性大細胞型B細胞リンパ腫, リンパ腫-大細胞, リンパ腫-びまん性大細胞-B細胞性, びまん性大細胞型Bリンパ腫, 瀰漫性大細胞型B細胞リンパ腫, 大細胞リンパ腫, びまん性大リンパ様リンパ腫, びまん性組織球性リンパ腫, リンパ腫-大細胞-瀰漫性, 大濾胞中心細胞びまん性リンパ腫, 大細胞型びまん性リンパ腫, 大細胞型びまん性未分化リンパ腫, 汎発性大細胞リンパ腫, 瀰漫性大細胞リンパ腫, 組織球性びまん性リンパ腫, びまん性大濾胞中心細胞リンパ腫, びまん性大細胞リンパ腫, びまん性大細胞型リンパ腫, びまん性未分化大細胞リンパ腫, び漫性大細胞リンパ腫, び漫性性組織球性リンパ腫, リンパ腫-びまん性-大濾胞中心細胞, リンパ腫-びまん性-大細胞型, リンパ腫-びまん性-組織球性, リンパ腫-びまん性組織球性, リンパ腫-大リンパ様-びまん性, リンパ腫-大濾胞中心細胞-びまん性, リンパ腫-大細胞-びまん性, リンパ腫-大細胞-びまん性未分化, リンパ腫-大細胞-汎発性, リンパ腫-未分化大細胞-びまん性, リンパ腫-汎発性-大細胞型, リンパ腫-組織球性-びまん性, 大細胞リンパ腫-びまん性, 大細胞型瀰漫性未分化リンパ腫, 未分化リンパ腫-びまん性-大細胞型, 瀰漫性組織球性リンパ腫, 組織球性リンパ腫-びまん性
Swedish Lymfom, diffust storcelligt
Finnish Suurisoluinen diffuusi B-solulymfooma
Russian LIMFOMA DIFFUZNAIA KRUPNOKLETOCHNAIA, LIMFOMA GISTIOTSITARNAIA DIFFUZNAIA, DIFFUZNAIA KRUPNOKLETOCHNAIA B-KLETOCHNAIA LIMFOMA, ЛИМФОМА КРУПНОКЛЕТОЧНАЯ, ЛИМФОМА КРУПНОКЛЕТОЧНАЯ ДИФФУЗНАЯ, LIMFOMA KRUPNOLIMFOIDNAIA DIFFUZNAIA, GISTIOTSITARNAIA LIMFOMA DIFFUZNAIA, LIMFOMA GISTIOTSITARNAIA, ЛИМФОМА ГИСТИОЦИТАРНАЯ, LIMFOMA KRUPNOKLETOCHNAIA, SARKOMA RETIKULOKLETOCHNAIA, LIMFOMA B-KRUPNOKLETOCHNAIA DIFFUZNAIA, САРКОМА РЕТИКУЛОКЛЕТОЧНАЯ, ЛИМФОМА B-КРУПНОКЛЕТОЧНАЯ ДИФФУЗНАЯ, ДИФФУЗНАЯ КРУПНОКЛЕТОЧНАЯ B-КЛЕТОЧНАЯ ЛИМФОМА, LIMFOMA DIFFUZNAIA KRUPNOFOLLIKULIARNAIA TSENTRAL'NAIA, LIMFOMA KRUPNOKLETOCHNAIA DIFFUZNAIA, LIMFOMA KRUPNOKLETOCHNAIA DIFFUZNAIA NEDIFFERENTSIROVANNAIA, ГИСТИОЦИТАРНАЯ ЛИМФОМА ДИФФУЗНАЯ, ЛИМФОМА ГИСТИОЦИТАРНАЯ ДИФФУЗНАЯ, ЛИМФОМА ДИФФУЗНАЯ КРУПНОКЛЕТОЧНАЯ, ЛИМФОМА ДИФФУЗНАЯ КРУПНОФОЛЛИКУЛЯРНАЯ ЦЕНТРАЛЬНАЯ, ЛИМФОМА КРУПНОКЛЕТОЧНАЯ ДИФФУЗНАЯ НЕДИФФЕРЕНЦИРОВАННАЯ, ЛИМФОМА КРУПНОЛИМФОИДНАЯ ДИФФУЗНАЯ
Czech Difuzní velkobuněčné B-lymfomy, Difuzní velkobuněčný B-lymfom, Difuzní velkobuněčný B-lymfom NOS, lymfom velkobuněčný difuzní, lymfom histiocytární, lymfom velkobuněčný, z B-buněk, difuzní, velkobuněčný difusní lymfom B řady, difúzní velkobuněčný B-lymfom, difúzní B-velkobuněčný lymfom, histiocytický lymfom
Korean 대세포(미만성)비호지킨 림프종
Polish Chłoniak rozsiany histiocytowy, Chłoniak histiocytowy rozlany, Chłoniak rozlany z dużych komórek B, Chłoniak z komórek olbrzymich, Chłoniak histiocytowy, Chłoniak z komórek dużych niezróżnicowany rozsiany, Chłoniak z komórek olbrzymich rozlany, Chłoniak B-wielkokomórkowy rozlany, Chłoniak rozsiany limfoidalny
Croatian LIMFOM VELIKIH B STANICA, DIFUZNI, LIMFOM VELIKIH B-STANICA, DIFUZNI
Hungarian Diffúz nagy B-sejtes lymphomák, Diffúz nagy B-sejtes lymphoma, Diffúz nagy B-sejtes lymphoma k.m.n.
Norwegian Diffust storcellet B-cellelymfom

Ontology: Precursor cell lymphoblastic lymphoma (C0079748)

Definition (NCI) A lymphoma composed of immature small to medium-sized precursor lymphoid cells (lymphoblasts). It includes the B- and T-cell lymphoblastic lymphoma.
Definition (NCI_CDISC) A malignant neoplasm composed of lymphoblasts (lymphoid precursor cells).
Definition (NCI_NCI-GLOSS) An aggressive (fast-growing) type of non-Hodgkin lymphoma in which too many lymphoblasts (immature white blood cells) are found in the lymph nodes and the thymus gland. These lymphoblasts may spread to other places in the body. It is most common in teenagers and young adults and affects more males than females. It may be a T or B cell type.
Concepts Neoplastic Process (T191)
ICD10 M9685/3 , C83.5
SnomedCT 109965004, 8175003, 189972001, 312281000009102, 188675007, 128806000
English Malig lymphoma - lymphoblastic, Lymphoblastic (diffuse), Lymphoblastic (diffuse) non-Hodgkin's lymphoma, [M]Lymphoblastic lymphoma NOS, Diffuse non-Hodgkin's lymphoma, lymphoblastic, Precursor cell lymphoblastic lymphoma, diffuse lymphoblastic lymphoma (LL), diffuse lymphoblastic lymphoma (LL) (diagnosis), lymphoblastic lymphoma (LL), Precursor Lymphoblastic Lymphoma, Lymphoblastic Lymphoma, Diffuse non-Hodgkin lymphoma, lymphoblastic, Lymphoblastic lymphoma NOS, Lymphoblastic (diffuse) lymphoma, lymphoblastic lymphoma, lymphoma lymphoblastic, Lymphoblastic lymphoma, diffuse, Malignant lymphoma, lymphoblastic (morphologic abnormality), Lymphoblastic lymphoma (disorder), PRECURSOR LYMPHOBLASTIC LYMPHOMA, PRECURSOR CELL LYMPHOBLASTIC LYMPHOMA, precursor lymphoblastic lymphoma, LYMPHOMA, LYMPHOBLASTIC, MALIGNANT, Lymphoblastic lymphoma, Lymphoblastic lymphosarcoma, Lymphoblastoma, Malignant lymphoma - lymphoblastic, Malignant lymphoma, lymphoblastic, Diffuse non-Hodgkin's lymphoma, lymphoblastic (clinical), Diffuse non-Hodgkin's lymphoma, lymphoblastic (disorder), Lymphoblastoma [obs], Malignant lymphoma, convoluted cell [obs], Precursor cell lymphoblastic lymphoma (morphologic abnormality), lymphoblastic; lymphoma, lymphoblastoma, lymphoma; lymphoblastic, Malignant lymphoma, convoluted cell, Malignant lymphoma, lymphoblastic -RETIRED-, Precursor Cell Lymphoblastic Lymphoma, Diffuse lymphoblastic lymphoma, Diffuse lymphoblastic malignant lymphoma, Diffuse lymphoblastic lymphosarcoma, Diffuse lymphoblastoma, Lymphoblastic malignant lymphoma
Spanish linfoma no hodgkiniano difuso, linfoblástico, Linfoma linfoblástico, linfoma no hodgkiniano difuso, linfoblástico (clínico), linfoma linfoblástico difuso, linfoma no Hodgkin difuso, linfoblástico (clínico), linfoma no Hodgkin difuso, linfoblástico (clínico) (trastorno), linfoma no hodgkiniano difuso, linfoblástico (trastorno), linfoma maligno, células convolutas, linfoma maligno, linfoblástico (concepto no activo), linfoblastoma, linfoma linfoblástico de células precursoras (anomalía morfológica), linfoma linfoblástico de células precursoras, linfoma maligno, de células contorneadas, linfoma maligno, linfoblástico, linfosarcoma linfoblástico
Dutch lymfoblastisch lymfoom, lymfoblastair; lymfoom, lymfoom; lymfoblastair, Non-Hodgkin-lymfoom, lymfoblastair (diffuus)
French Lymphome lymphoblastique
German lymphoblastisches Lymphom, Non-Hodgkin-Lymphom: Lymphoblastisch (diffus)
Italian Linfoma linfoblastico
Portuguese Linfoma linfoblástico
Japanese リンパ芽球性リンパ腫, リンパガキュウセイリンパシュ
Czech Lymfoblastický lymfom
Korean 림프모세포성(미만성)비호지킨 림프종
Hungarian Lymphoblastos lymphoma

Ontology: T-Cell Lymphoma (C0079772)

Definition (NCI_NCI-GLOSS) A disease in which certain cells of the lymph system (called T lymphocytes) become cancer.
Definition (NCI) A non-Hodgkin lymphoma of T-cell lineage. It includes the T lymphoblastic lymphoma and the mature T- and NK-cell lymphomas. -- 2003
Definition (MSH) A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes.
Concepts Neoplastic Process (T191)
MSH D016399
SnomedCT 109978004, 3172003
English Lymphoma, T Cell, Lymphoma, T-Cell, Lymphomas, T-Cell, T-Cell Lymphomas, T-Cell Non-Hodgkin's Lymphoma, T-Cell and NK-Cell Non-Hodgkin Lymphoma, T-Cell Non-Hodgkin Lymphoma, T-cell lymphoma NOS, Lymphoma, T-Cell [Disease/Finding], cells lymphoma t, lymphoma t-cell, cell lymphomas t, lymphoma t cell, cell lymphoma t, t cell lymphoma, t-cell lymphoma, Lymphomas non-Hodgkin's T-cell, malignant neoplasm lymphoma t-cell, T-cell lymphoma (diagnosis), T-cell lymphoma, T-cell lymphoma (clinical), T-cell lymphoma (disorder), T-cell; lymphoma, lymphoma; T-cell, T Cell Lymphoma, Non-Hodgkin's T-Cell Lymphoma, T-Cell and NK-Cell Non-Hodgkin's Lymphoma, T-Cell Lymphoma
Spanish linfoma de células T, linfoma de linfocitos T, Linfoma de células T NEOM, linfoma de linfocitos T (clínico), linfoma de linfocitos T (trastorno), Linfoma de células T, Linfomas no hodgkinianos de células T, Linfoma de Células T, Linfoma T
Italian Linfomi non-Hodgkin a cellule T, Linfoma a cellule T NAS, Linfoma a cellule T
Dutch T-cellymfoom NAO, T-cel; lymfoom, lymfoom; T-cel, non-Hodgkin T-cel lymfomen, Lymfoom, T-cel-, T-cellymfoom
French Lymphome T SAI, Lymphomes non hodgkiniens à cellules T, Lymphome T, Lymphome à cellules T
German T-Zell-Lymphom NNB, Non-Hodgkin-T-Zell-Lymphome, Lymphom, T-Zell-, T-Zell-Lymphom
Portuguese Linfoma de células T NE, Linfoma de células T, Linfoma não-Hodgkin de células T, Linfoma de Células T, Linfoma T
Japanese 非ホジキンT細胞性リンパ腫, T細胞性リンパ腫, T細胞性リンパ腫NOS, Tサイボウセイリンパシュ, TサイボウセイリンパシュNOS, ヒホジキンTサイボウセイリンパシュ, T細胞性リンパ腫, リンパ腫-T細胞性, T細胞リンパ腫
Swedish T-cellslymfom
Czech T-lymfom, lymfom z T-buněk, lymfom T-buněčný, T-buněčný lymfom NOS, Nehodgkinské T-lymfomy, T-buněčný lymfom
Finnish T-solulymfooma
Russian LIMFOMA T-KLETOCHNAIA, T-KLETOCHNAIA LIMFOMA, T-КЛЕТОЧНАЯ ЛИМФОМА, ЛИМФОМА T-КЛЕТОЧНАЯ
Polish Chłoniak T-komórkowy
Hungarian T-sejtes lymphoma, Lymphomás nem-Hodgkin T-sejt, T-sejtes lymphoma k.m.n.
Norwegian T-cellelymfom
Croatian Limfom T-stanica

Ontology: Peripheral T-Cell Lymphoma (C0079774)

Definition (NCI) Aggressive nodal or extranodal mature (peripheral) T-cell lymphomas that do not belong to the better defined entities of the remainder of mature T-cell lymphomas. This category includes the following variants: lymphoepithelioid cell variant (Lennert's lymphoma), follicular variant, and T-zone variant.
Definition (NCI) This type of lymphoma is not frequently seen in the western hemisphere. Clinically, with the exception of anaplastic large cell lymphoma, mature T- and NK-cell lymphomas are among the most aggressive of all hematopoietic neoplasms. Representative disease entities include mycosis fungoides, angioimmunoblastic T-cell lymphoma, hepatosplenic T-cell lymphoma, and anaplastic large cell lymphoma.
Definition (NCI_NCI-GLOSS) One of a group of aggressive (fast-growing) non-Hodgkin lymphomas that begins in mature T lymphocytes (T cells that have matured in the thymus gland and goes to other lymphatic sites in the body, including lymph nodes, bone marrow, and spleen.)
Definition (MSH) A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment.
Concepts Neoplastic Process (T191)
MSH D016411
ICD9 202.7
ICD10 C84.4 , M9702/3, C84.9, C84
SnomedCT 109977009, 3172003, 188688005, 190008008
English Lymphoma, Peripheral T-Cell, Lymphoma, T Cell, Peripheral, Lymphoma, T-Cell, Peripheral, Lymphomas, Peripheral T-Cell, Peripheral T Cell Lymphoma, Peripheral T-Cell Lymphomas, T Cell Lymphoma, Peripheral, T-Cell Lymphoma, Peripheral, T-Cell Lymphomas, Peripheral, Peripheral T-cell lymphoma NOS, [M] Peripheral T-cell lymphoma, [M] Peripheral T-cell lymphoma NOS, Mature T-Cell and NK-Cell Non-Hodgkin's Lymphoma, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, mature T-cell lymphoma, mature T-cell lymphoma (diagnosis), Peripheral T-cell lymphoma, no ICD-O subtype, Peripheral T-cell lymphoma unspecified NOS, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Peripheral T-Cell Lymphoma, NOS, Peripheral T-Cell Lymphoma, Mature T/NK-cell lymphomas, unspecified, Mature T/NK-cell lymphomas, Lymphoma, T-Cell, Peripheral [Disease/Finding], peripheral t-cell lymphoma, peripheral t cell lymphoma, cell lymphomas peripheral t, [M] Peripheral T-cell lymphoma NOS (morphologic abnormality), mature NK/T-cell lymphoma (diagnosis), mature NK/T-cell lymphoma, malignant neoplasm lymphoma mature nk/t-cell, Peripheral T-cell lymphoma, no International Classification of Diseases for Oncology subtype (morphologic abnormality), Peripheral T-cell lymphoma, no ICD-O subtype (morphologic abnormality), Peripheral T-cell lymphoma, no International Classification of Diseases for Oncology subtype, peripheral T-cell lymphoma, Peripheral T-cell lymphoma, NOS, Peripheral T-cell lymphoma, Mature T-cell lymphoma, Peripheral T-cell lymphoma (clinical), Peripheral T-cell lymphoma (disorder), T-cell; lymphoma, peripheral, lymphoma; T-cell, peripheral, lymphoma; peripheral T-cell, peripheral; T-cell lymphoma, Mature T-Cell Non-Hodgkin's Lymphoma, Mature T-Cell and NK-Cell Lymphoma, Mature T-and NK-Cell Lymphoma, PTCL, Peripheral T-cell lymphoma (morphologic abnormality), Peripheral T-cell lymphoma unspecified
Spanish linfoma periférico de linfocitos T, Linfoma periférico de células T no especificado NEOM, linfoma periférico de linfocitos T (anomalía morfológica), linfoma periférico de linfocitos T, microcelular (células pleomorfas), linfoma periférico de linfocitos T, no clasificado como subtipo en CIE-O, linfoma periférico de linfocitos T, sin subtipo CIE-O (anomalía morfológica), linfoma periférico de linfocitos T, no clasificado como subtipo en CIE-O (anomalía morfológica), linfoma periférico de linfocitos T, sin subtipo CIE-O, [M]linfoma de células T periféricas, SAI, [M]linfoma de células T periféricas, SAI (anomalía morfológica), linfoma de linfocitos T maduros, linfoma periférico de linfocitos T (clínico), linfoma periférico de linfocitos T (trastorno), Linfoma periférico de células T no especificado, Linfoma de Células T Periféricas, Linfoma de Células T Periférico, Linfoma Periférico de Células T
Italian Linfoma a cellule T periferico non specificato, Linfoma a cellule T periferico non specificato, NAS, Linfoma periferico a cellule T
Dutch perifeer T-cellymfoom niet-gespecificeerd NAO, T-cel; lymfoom, perifeer, lymfoom; T-cel, perifeer, lymfoom; perifeer T-cel, perifeer; T-cel-lymfoom, Perifeer T-cel-lymfoom, perifeer T-cellymfoom niet-gespecificeerd, Lymfoom, perifeer T-cel-, Perifeer T-cellymfoom, T-cellymfoom, perifeer
French Lymphome T périphérique non précisé SAI, Lymphome T périphérique non précisé, Lymphome T périphérique, Lymphome périphérique à cellules T
German peripheres T-Zell-Lymphom unspezifisch NNB, T-Zell-Lymphom, peripher, peripheres T-Zell-Lymphom unspezifisch, Lymphom, T-Zell-, peripheres, Peripheres T-Zell-Lymphom, T-Zell-Lymphom, peripheres
Portuguese Linfoma de células T periféricas NE, Linfoma de Células T Periféricas, Linfoma de células T periféricas não especificado, Linfoma de Células T Periférico, Linfoma Periférico de Células T
Japanese 末梢性T細胞性リンパ腫、組織型不明NOS, 末梢性T細胞性リンパ腫、組織型不明, マッショウセイTサイボウセイリンパシュソシキガタフメイNOS, マッショウセイTサイボウセイリンパシュソシキガタフメイ, T細胞性リンパ腫-末梢性, リンパ腫-末梢性T細胞性, 末梢性T細胞性リンパ腫, 末端部T細胞リンパ腫, リンパ腫-T細胞性-末梢性, リンパ腫-T細胞性-末端部, リンパ腫-末端部T細胞, 末端部T細胞性リンパ腫
Swedish T-cellslymfom, perifert
Czech lymfom z T-buněk periferní, lymfom T-buněčný periferní, Periferní T-lymfom blíže neurčený NOS, Periferní T-lymfom blíže neurčený
Finnish Perifeerinen T-solulymfooma
Russian T-KLETOCHNAIA LIMFOMA PERIFERICHESKAIA, LIMFOMA T-KLETOCHNAIA PERIFERICHESKAIA, T-КЛЕТОЧНАЯ ЛИМФОМА ПЕРИФЕРИЧЕСКАЯ, ЛИМФОМА T-КЛЕТОЧНАЯ ПЕРИФЕРИЧЕСКАЯ
Korean 말초성 T-세포 림프종
Polish Chłoniak T-komórkowy obwodowy
Hungarian Peripheriás T-sejtes lymphoma nem meghatározott k.m.n., Peripheriás T-sejtes lymphoma nem meghatározott
Norwegian Perifert T-cellelymfom

Ontology: Marginal Zone B-Cell Lymphoma (C1367654)

Definition (NCI) A usually indolent mature B-cell lymphoma, arising from the marginal zone of lymphoid tissues. It is characterized by the presence of small to medium sized atypical lymphocytes. It comprises three entities, according to the anatomic sites involved: extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, which affects extranodal sites (most often stomach, lung, skin, and ocular adnexa); nodal marginal zone B-cell lymphoma, which affects lymph nodes without evidence of extranodal disease; and splenic marginal zone B-cell lymphoma, which affects the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood.
Definition (NCI_NCI-GLOSS) An indolent (slow-growing) type of B-cell non-Hodgkin lymphoma that begins forming in certain areas (the marginal zones) of lymph tissue. There are three types based on whether it forms in the spleen, lymph nodes, or other lymphoid tissue that contains a lot of B cells (a type of white blood cell).
Concepts Neoplastic Process (T191)
ICD9 200.3
SnomedCT 103683000, 447100004, 128803008
English Marginal Zone B-Cell Lymphoma, marginal zone lymphoma (diagnosis), marginal zone B-cell lymphoma, marginal zone B-cell lymphoma (diagnosis), marginal zone lymphoma, Marginal Zone Lymphoma, Marginal zone lymphoma (disorder), Marginal zone lymphoma, Marginal zone lymphoma (morphologic abnormality), MZL, Marginal zone B-cell lymphoma (morphologic abnormality), Marginal zone B-cell lymphoma, Marginal zone lymphoma, NOS, Marginal zone lymphoma -RETIRED-, MZBCL
Spanish linfoma de la zona marginal (trastorno), linfoma de la zona marginal, linfoma de zona marginal (concepto no activo), linfoma de zona marginal, linfoma de linfocitos B de la zona marginal (anomalía morfológica), linfoma de linfocitos B de la zona marginal, linfoma ganglionar de la zona marginal, linfoma monocitoide de linfocitos B