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Definition (MSH)
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Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
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Definition (MSHCZE)
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Lymfocyty získané z kostní dřeně, které mají cytotoxické vlastnosti, přirozeně namířené proti transformovaným buňkám a buňkám infikovaným virem. NK buňky nejsou na rozdíl od T buněk a B buněk antigenově specifické (projevuje se nespecifickou imunitou). Cytotoxicita těchto buněk je zajištěna pomocí receptorů na povrchu buněk, které společně signalizují stavy inhibice a stimulace buněk. Jedná se o podskupina T-LYMPHOCYTŮ, která bývá označována jako „přirození zabíječi“ (NKT BUŇKY) (angl. natural killers) a sdílí s těmito buňkami některé vlastnosti. R
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Definition (NCI)
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Natural killer cells are cells that resemble large granular lymphocytes. They do not express markers of either T or B cell lineage. They are positive for CD16, CD56, and CD 94. These cells do possess Fc receptors for IgG and can kill target cells using antibody-dependent cell-mediated cytotoxicity. They can also use perforin to kill cells in the absence of antibody and killing may occur without previous sensitization.
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Definition (NCI_NCI-GLOSS)
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A type of immune cell that has granules (small particles) with enzymes that can kill tumor cells or cells infected with a virus. A natural killer cell is a type of white blood cell.
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Definition (PSY)
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White blood cells that kill tumor- and virus-infected cells as part of the body's immune system.
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Definition (CSP)
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type of cytotoxic leukocytes which attack and kill virus-infected or neoplastic cells independent of antibody coating or MHC restriction; may be derived from lymphocytes or monocytes.
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| Concepts |
Cell
(T025)
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| MSH |
D007694
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| SnomedCT |
259717003
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| LNC |
LA4573-7 |
| English |
Cell, Natural Killer, Cell, NK, Cells, Natural Killer, Cells, NK, Killer Cell, Natural, Killer Cells, Natural, NK Cells, K lymphocyte, Killer cell, K cell, NK-cell (cell), Natural killer (NK)-cell, Natural killer cell, NK cell, nk cell, nk-cell, natural killer cells, nk cells, cells natural killer, Natural killer cell (cell), Natural killer (NK)-cell (cell), natural killer cell, NK-LGL, killer cell, NK (natural killer) cell, NK-cell, NK-cell (body structure), Natural Killer Cell, NK Cell, Killer Cell, NK-Cell, NK, Natural Killer Cells |
| Spanish |
célula NK, linfocito K, Células Asesinas Naturales, Células Killer Naturales, célula natural killer, célula asesina natural, Células Killer, linfocito citolítico natural (célula), linfocito citolítico natural, Células NK |
| French |
Cellule tueuse naturelle, Cellules tueuses naturelles, Cellules NK, Cellule NK |
| Swedish |
Mördarceller, naturliga
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| Czech |
buňky NK, buňky natural killer |
| Finnish |
Luonnolliset tappajasolut
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| Italian |
Cellule NK, Cellule Natural Killer |
| Russian |
KLETKI-KILLERY ESTESTVENNYE, NK-KLETKI, ESTESTVENNYE KLETKI-KILLERY, K-KLETKI, KILLERNYE KLETKI, КИЛЛЕРНЫЕ КЛЕТКИ, K-КЛЕТКИ, NK-КЛЕТКИ, ЕСТЕСТВЕННЫЕ КЛЕТКИ-КИЛЛЕРЫ, КЛЕТКИ-КИЛЛЕРЫ ЕСТЕСТВЕННЫЕ |
| Japanese |
NK細胞, キラー細胞-ナチュラル, ナチュラルキラー細胞 |
| Croatian |
PRIROĐENO UBILAČKE STANICE
|
| Polish |
Komórki NK, Komórki natural killer, Komórka-naturalny zabójca, Komórki naturalnej cytotoksyczności |
| Norwegian |
Natural killer-celler, Drepeceller, naturlige, Naturlige drapsceller, Drapsceller, naturlige, Naturlige drepeceller, NK-celler |
| Portuguese |
Células Exterminadoras, Células Destruidoras, Células Killer, Células Natural Killer, Células Destruidoras Naturais, Células Assassinas, Células Killer Naturais, Células Assassinas Naturais, Células Exterminadoras Naturais, Células NK, Células Matadoras Naturais |
| German |
NK-Zellen, Killerzellen, natürliche, Natürliche Killerzellen |
| Dutch |
K-cel, Killercellen, Natural-killercel, Natural-killercellen |
