II. Background

  1. Measures the Common Clotting Pathway
  2. Measures the rate of Clot Formation in anticoagulated blood when Thrombin is added
  3. Results for an individual patient are compared with those of pooled blood from multiple normal patients

III. Labs: Normal

  1. Range: 11.3-18.5 seconds

IV. Causes: Increased

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Ontology: Thrombin Time Assay (C0677634)

Definition (MSHCZE) Zkr. TT – test k vyšetření koagulace krve. Vyšetřuje se jím závěrečná fáze koagulační kaskády, konverze fibrinogenu na fibrin po přidání exogenního trombinu. Trvá cca do 20 sekund. Prodloužen je při poruchách fibrinu, hypofibrinogenemii či afibrinogenemii či při přítomnosti FDP. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
Definition (NCI) A measurement of the time it takes a plasma sample to clot after adding the active enzyme thrombin.
Definition (NCI_CDISC) A measurement of the time it takes a plasma sample to clot after adding the active enzyme thrombin. (NCI)
Definition (MSH) Clotting time of PLASMA mixed with a THROMBIN solution. It is a measure of the conversion of FIBRINOGEN to FIBRIN, which is prolonged by AFIBRINOGENEMIA, abnormal fibrinogen, or the presence of inhibitory substances, e.g., fibrin-fibrinogen degradation products, or HEPARIN. BATROXOBIN, a thrombin-like enzyme unaffected by the presence of heparin, may be used in place of thrombin.
Concepts Laboratory Procedure (T059)
MSH D013918
SnomedCT 393771009, 392816005, 142982000, 55323000, 103853006, 3717006
CPT 85670, 1011864
English Reptilase Time, Reptilase Times, Thrombin Time, Thrombin Times, Time, Reptilase, Time, Thrombin, Times, Reptilase, Times, Thrombin, Thrombin time; plasma, TCT, thrombin clotting time, thrombin time, reptilase time, reptilase time (lab test), Thrombin Time Assay, thrombin time (lab test), reptilase time test, Thrombin clotting time, TT, Thrombin Clotting Time, Test;thrombin time, tct, Thrombin time plasma, THROMBIN TIME PLASMA, Thrombin time test on plasma, Reptilase clotting time (procedure), Plasma Thrombin Test, Fibrin time, Reptilase time, Thrombin time, Reptilase clotting time, TT - Thrombin time, Reptilase time (procedure), Thrombin time (procedure), Thrombin time - observation, thrombin time test
Dutch TCT (trombine stollingstijd), trombine stollingstijd, trombinetijd, Reptilasetijd, Trombinetijd
French TT (Temps de thrombine), Temps de reptilase, Temps de thrombine, TR (Temps de Reptilase)
German TCT, Thrombingerinnungszeit, Reptilasezeit, Thrombinzeit
Italian Tempo di coagulazione della trombina, Tempo di reptilasi, Tempo di trombina
Spanish TCT, Tiempo de coagulación de trombina, tiempo de coagulación con reptilasa, tiempo de fibrina, tiempo de reptilasa (procedimiento), tiempo de reptilasa, tiempo de trombina (procedimiento), tiempo de trombina, Tiempo de trombina, Tiempo de Reptilasa, Tiempo de Trombina
Japanese トロンビン凝固時間, トロンビンジカン, トロンビンギョウコジカン, トロンビン時間, レプチラーゼ時間
Swedish Trombintid
Finnish Trombiiniaika
Russian REPTILAZOVOE VREMIA, TROMBINOVOE VREMIA, РЕПТИЛАЗОВОЕ ВРЕМЯ, ТРОМБИНОВОЕ ВРЕМЯ
Czech Trombinový čas, Trombinový koagulační čas, thrombinový čas, trombinový čas
Polish Czas trombinowy
Hungarian TCT, Thrombin idő, Thrombin alvadási idő
Norwegian Trombintid, Reptilasetid
Portuguese Tempo de trombina, Tempo de Reptilase, Tempo de Trombina