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Ontology: Alzheimer's Disease (C0002395)

Definition (MEDLINEPLUS)

Alzheimer's disease (AD) is the most common form of dementia among older people. Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities.

AD begins slowly. It first involves the parts of the brain that control thought, memory and language. People with AD may have trouble remembering things that happened recently or names of people they know. A related problem, mild cognitive impairment (MCI), causes more memory problems than normal for people of the same age. Many, but not all, people with MCI will develop AD.

In AD, over time, symptoms get worse. People may not recognize family members or have trouble speaking, reading or writing. They may forget how to brush their teeth or comb their hair. Later on, they may become anxious or aggressive, or wander away from home. Eventually, they need total care. This can cause great stress for family members who must care for them.

AD usually begins after age 60. The risk goes up as you get older. Your risk is also higher if a family member has had the disease.

No treatment can stop the disease. However, some drugs may help keep symptoms from getting worse for a limited time.

NIH: National Institute on Aging

Definition (NCI) A progressive, neurodegenerative disease characterized by loss of function and death of nerve cells in several areas of the brain leading to loss of cognitive function such as memory and language.
Definition (NCI_NCI-GLOSS) A brain disorder that usually starts in late middle age or old age and gets worse over time. Symptoms include loss of memory, confusion, difficulty thinking, and changes in language, behavior, and personality.
Definition (MSH) A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
Definition (CSP) neurodegenerative disorder of the CNS resulting in progressive loss of memory and intellectual functions; begins in the middle or later years; characterized by brain lesions such as neurofibrillary tangles and neuritic plaques.
Concepts Disease or Syndrome (T047)
MSH D000544
ICD9 331.0
ICD10 G30 , G30.9
SnomedCT 73768007, 26929004, 267688001, 154998003
LNC MTHU020798
English Alzheimer Disease, Alzheimer's Disease, Dementia, Senile, Disease, Alzheimer, Disease, Alzheimer's, ALZHEIMER'S DISEASE, Senile Dementia, DAT - Dementia Alzheimer type, DAT - Dementia Alzheimer's type, Dementia in Alzheimer's dis, Dementia in Alzheimer's disease, Alzheimer's disease, unspecified, Alzheimer's Dementia, AD, ALZHEIMER DISEASE, ALZHEIMER DIS, ALZHEIMERS DIS, Alzheimer's disease, NOS, simple senile dementia, Dementia of the Alzheimer's type NOS, Alzheimer Type Senile Dementia, Senile Dementia, Alzheimer Type, Alzheimer Type Dementia, Dementia, Alzheimer Type, Alzheimer disease, Alzheimer Disease [Disease/Finding], alzheimers disease, dats, senile dementia, Alzheimers dementia, Disease;Alzheimers, alzheimers dementia, alzheimer diseases, alzheimer's diseases, dementia alzheimers, Dementia, Primary Senile Degenerative, Alzheimers disease, Syndrome, Alzheimer, Dementia, Alzheimer (AD), Alzheimer Syndrome, Dementia, Alzheimer-Type (ATD), Alzheimer Sclerosis, Alzheimer-Type Dementia (ATD), Alzheimer Type Dementia (ATD), Alzheimer Dementia (AD), Sclerosis, Alzheimer, Alzheimer's disease (diagnosis), Alzheimer dementia, Dementia Alzheimer's type, Alzheimer's disease, AD - Alzheimer's disease, Alzheimer's disease (disorder), Alzheimer; dementia (etiology), Alzheimer; dementia (manifestation), Alzheimer; sclerosis, Alzheimer, dementia; Alzheimer (etiology), dementia; Alzheimer (manifestation), sclerosis; Alzheimer, Alzheimers Disease, Dementia of Alzheimers Type, Dementia of the Alzheimer's type, Primary Senile Degenerative Dementia
Portuguese DOENCA DE ALZHEIMER, Demência tipo Alzheimer NE, Demência de tipo Alzheimer, Demência Senil, Demência Senil Tipo Alzheimer, Demência Tipo Alzheimer, Doença de Alzheimer
Spanish ENFERMEDAD DE ALZHEIMER, Demencia de tipo Alzheimer NEOM, enfermedad de Alzheimer (trastorno), enfermedad de Alzheimer, Demencia de tipo Alzheimer, Enfermedad de Alzheimer, Demencia Senil, Demencia Senil Tipo Alzheimer, Demencia Tipo Alzheimer
Dutch dementie van Alzheimer type NAO, ziekte van Alzheimer, Alzheimer; dementie, Alzheimer; sclerose, dementie; Alzheimer, sclerose; Alzheimer, Ziekte van Alzheimer, niet gespecificeerd, dementie type Alzheimer, Dementie, Alzheimer-type, Dementie, seniele, Seniele dementie, Alzheimer-type, Ziekte van Alzheimer
French Démence de type Alzheimer SAI, MALADIE D'ALZHEIMER, Démence de type Alzheimer, Démence d'Alzheimer, Maladie d'Alzheimer, Démence dégénérative primaire de type Alzheimer, Démence sénile primitive de type Alzheimer, Démence sénile primitive dégénérative
German Demenz vom Alzheimer Typ NNB, ALZHEIMERSCHE ERKRANKUNG, Alzheimer-Krankheit, nicht naeher bezeichnet, Demenz vom Alzheimertyp, Alzheimer-Krankheit, Dementia senilis, Demenz, senile, Demenz, Alzheimer-Typ, Senile Demenz, Alzheimer-Typ, Demenz, primär degenerative senile, Primär degenerative senile Demenz
Italian Demenza tipo Alzheimer NAS, Demenza tipo Alzheimer, Demenza senile tipo Alzheimer, Demenza senile, Demenza degenerativa primaria senile, Malattia di Alzheimer
Japanese アルツハイマー型認知症NOS, アルツハイマーガタニンチショウ, アルツハイマーガタニンチショウNOS, アルツハイマービョウ, Alzheimer型認知症, 初老期認知症-Alzheimer型, アルツハイマー型認知症, アルツハイマー型老年痴呆, 痴呆-アルツハイマー型, アルツハイマー型痴呆-初老期, 老年期認知症-Alzheimer型, Alzheimer型痴呆, 初老期アルツハイマー型痴呆, アルツハイマー病, 認知症-Alzheimer型, アルツハイマー型初老期痴呆, 老年一次性変性痴呆, アルツハイマー型痴呆, 初老期痴呆-Alzheimer型, 老年期痴呆-アルツハイマー型, 一次痴呆, 急性錯乱性老年性痴呆, 初老期痴呆-アルツハイマー型, 痴呆-一次性変性-老年, 老年期痴呆-Alzheimer型, Alzheimer型老年期痴呆, アルツハイマー型老年期痴呆, 痴呆-Alzheimer型, Alzheimer病, Alzheimer型初老期痴呆
Swedish Alzheimers sjukdom
Czech Alzheimerova nemoc, Demence Alzheimerova typu, Demence Alzheimerova typu NOS, Fischerova nemoc, Alzheimerova choroba, senilní demence Alzheimerova typu, Alzheimerova demence, senilní demence
Finnish Alzheimerin tauti
Korean 알쯔하이머병, 상세불명의 알쯔하이머병
Polish Choroba Alzheimera
Hungarian Alzheimer típusú dementia k.m.n., Alzheimer-kór, Alzheimer-típusú dementia
Norwegian Alzheimers sykdom, Alzheimers lidelse