II. Physiology

III. Interpretation: Normal Values per age (-2 to +2 S.D)

  1. Birth: 13.5 to 24.0 g/dl (mean 16.5 g/dl)
  2. Age <1 month: 10.0 to 20.0 g/dl (mean 13.9 g/dl)
  3. Age 1-2 months: 10.0 to 18.0 g/dl (mean 11.2 g/dl)
  4. Age 2-6 months: 9.5 to 14.0 g/dl (mean 12.6 g/dl)
  5. Age 0.5 to 2 years: 10.5 to 13.5 g/dl (mean 12.0 g/dl)
  6. Age 2 to 6 years: 11.5 to 13.5 g/dl (mean 12.5 g/dl)
  7. Age 6-12 years: 11.5 to 15.5 g/dl (mean 13.5)
  8. Male
    1. Age 12-18 years: 13.0 to 16.0 g/dl (mean 14.5 g/dl)
    2. Age >18 years: 13.6 to 17.7 g/dl (mean 15.5 g/dl)
  9. Female
    1. Age 12-18 years: 12.0 to 16.0 g/dl (mean 14.0 g/dl)
    2. Age >18 years: 12.1 to 15.1 g/dl (mean 14.0 g/dl)

IV. Interpretation: Anemia Cut-offs

  1. Men and adolescent males
    1. Age 12-18 years: <13 g/dl (mean 14.5 g/dl)
    2. Age >18 years: <13 g/dl (WHO) or <13.5 g/dl (CDC)
  2. Women and adolescent girls (Non-pregnant, non-lactating)
    1. Age 12-18 years: <12 g/dl (mean 14 g/dl)
    2. Age >18 years: <12 g/dl (WHO and CDC)
  3. Women in Pregnancy (CDC Guidelines <5th percentile)
    1. First Trimester: <11.0 g/dl
    2. Second Trimester: <10.5 g/dl
    3. Third Trimester: <11.0 g/dl
  4. Children (CDC Guidelines <5th percentile)
    1. Age 1-2 years: <10.5 g/dl
    2. Age 2-6 years: <11.5 g/dl (mean 12.5 g/dl)
    3. Age 6-12 years: <11.5 g/dl (mean 13.5 g/dl)
  5. Infants (2 S.D. below mean)
    1. Term (cord blood): <13.5 g/dl (mean 16.5 g/dl)
    2. Newborn (1-3 days): <14.5 g/dl (mean 18.5 g/dl)
    3. Age 2 weeks: <13.4 g/dl (mean 16.6 g/dl)
    4. Age 1 month: <10.7 g/dl (mean 13.9 g/dl)
    5. Age 2 months: <9.4 g/dl (mean 11.2 g/dl)
    6. Age 6 months: <10.5 g/dl (mean 12 g/dl)

V. Causes: Increased Hemoglobin

  1. Polycythemia Vera
  2. Vigorous Exercise
  3. High altitude

VI. Causes: Decreased Hemoglobin

  1. See Anemia

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Related Studies

Ontology: Hemoglobinopathies (C0019045)

Definition (MSHCZE) Nemoc, jejíž podstatou je tvorba vadného krevního barviva (hemoglobinu) v důsledku mutace v některém z hemoglobinových řetězců. Vadný hemoglobin hůře přenáší kyslík nebo mění vlastnosti červených krvinek. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
Definition (NCI) An inherited disorder characterized by structural alterations of a globin chain within the hemoglobin molecule.
Definition (MSH) A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
Definition (CSP) group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
Concepts Disease or Syndrome (T047)
MSH D006453
ICD10 D58.2
SnomedCT 267556002, 154794008, 80141007
LNC LP31618-9, MTHU029621, LA16207-5
English Hemoglobinopathies, hemoglobinopathies, Hemoglobinopathy NOS, hemoglobinopathy, hemoglobinopathy (diagnosis), Haemoglobinopathies congenital, Haemoglobinopathies, Haemoglobinopathy NOS, Hemoglobinopathies [Disease/Finding], haemoglobin disease, haemoglobinopathies, hemoglobin disease, hemoglobin disorder, diseases hemoglobin, disorders hemoglobin, haemoglobinopathy, hemoglobin disorders, Hemoglobin disorders, Hemoglobin disease, Hemoglobinopathy, Hemoglobin disorder, Haemoglobinopathy, Globin abnormality, Haemoglobin disease, Haemoglobin disorder, Hemoglobinopathy (disorder), Globin abnormality, NOS, Hemoglobin disease, NOS, Hemoglobin disorder, NOS, Hemoglobinopathy, NOS, Haemoglobin disease, NOS, Haemoglobin disorder, NOS, Haemoglobinopathy, NOS, Hemoglobinopathies / Iron Metabolism, Hemoglobinopathies congenital
Italian Emoglobinopatia, Emoglobinopatie congenite, Emoglobinopatia NAS, Emoglobinopatie
Dutch hemoglobinopathie NAO, hemoglobinopathie, hemoglobinopathieën, congenitaal, hemoglobinopathieën, Hemoglobinopathie, Hemoglobinopathieën
French Hémoglobinopathie SAI, Hémoglobinopathie, Hémoglobinopathies congénitales, Hémoglobinopathies, Maladies de l'hémoglobine
German Haemoglobinopathie NNB, Haemoglobinopathien, Haemoglobinopathie, Kongenitale Haemoglobinopathien, Hämoglobinopathien
Portuguese Hemoglobinopatia NE, Hemoglobinopatias congénitas, Hemoglobinopatia, Hemoglobinopatias
Spanish Hemoglobinopatía NEOM, alteración de la hemoglobina, hemoglobinopatía (trastorno), hemoglobinopatía, trastorno de la hemoglobina, Hemoglobinopatías congénitas, Hemoglobinopatía, Hemoglobinopatías
Japanese 異常ヘモグロビン症NOS, 先天性異常ヘモグロビン症, 異常ヘモグロビン症, イジョウヘモグロビンショウ, イジョウヘモグロビンショウNOS, センテンセイイジョウヘモグロビンショウ
Swedish Hemoglobinopatier
Czech hemoglobinopatie, Hemoglobinopatie, Vrozené hemoglobinopatie, Hemoglobinopatie NOS, Patologie hemoglobinu
Finnish Hemoglobinopatiat
Russian GEMOGLOBINOPATII, ГЕМОГЛОБИНОПАТИИ
Croatian HEMOGLOBINOPATIJE
Polish Hemoglobinopatie
Hungarian Haemoglobinopathiák, veleszületett, Haemoglobinopathia, Haemoglobinopathiák, Haemoglobinopathia k.m.n., Hemoglobinopatia
Norwegian Hemoglobinopati, Hemoglobinopatier

Ontology: Hemoglobin measurement (C0518015)

Definition (NCI) A quantitative measurement of the amount of hemoglobin present in a sample.
Definition (NCI_CDISC) A measurement of the hemoglobin in a biological specimen.
Concepts Laboratory Procedure (T059)
SnomedCT 35170002
CPT 85018, 83026, 88738, 1011483
English Hemoglobin, Haemoglobin, Haem, Hemoglobin Measurement, Hemoglobin measurement, hemoglobin, hemoglobin measurement (lab test), hemoglobin measurement, hemoglobin test, hemoglobin testing, Test;haemoglobin, hemoglobin tests, haemoglobin tests, test hemoglobin, BLOOD COUNT HEMOGLOBIN, Hemoglobin level, Measurement of hemoglobin (Hgb), Hemoglobin determination (procedure), Hemoglobin determination, Haemoglobin determination, HGB, Blood count; hemoglobin (Hgb), Hemoglobin determination, NOS, HEMOGLOBIN, Haemoglobin determination, NOS, Test;hemoglobin, haemoglobin test
Italian Emoglobina, Eme
Dutch haemoglobine, haem, hemoglobine
French Hémorr, Hémoglobine
German Haem, Haemoglobin
Portuguese Heme, Hemoglobina
Spanish Hemo, determinación de hemoglobina (procedimiento), determinación de hemoglobina, determinación de Hb, Hemoglobina
Japanese ヘモグロビン, ヘモグロビン
Czech Hem, Hemoglobin
Hungarian Haem, Haemoglobin, Hemoglobin