Eisenmenger's Complex

Aka: Eisenmenger's Complex, Eisenmenger Syndrome

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II. History

  1. First described by German physician in 1897

III. Pathophysiology

  1. Complication of untreated Ventricular Septal Defect
  2. Findings
    1. Ventricular Septal Defect
    2. Pulmonary Hypertension
    3. Right to left shunt
    4. Overriding aorta variably present

IV. Symptoms

  1. Dyspnea on exertion
  2. Fatigue
  3. Palpitations
  4. Hemoptysis

V. Signs

  1. Cyanosis
  2. Systolic Murmur in the 4th left intercostal interspace
  3. Accentuated P2 of the Second Heart Sound
  4. Finger Clubbing
  5. Accentuated precordial thrust of right ventricle

VI. Diagnostics: Electrocardiogram

  1. Right Axis Deviation
  2. Ventricular Hypertrophy

VII. Labs

  1. Hemoglobin increased (Erythrocytosis)

VIII. Complications

  1. Right Ventricular Failure
  2. Tricuspid regurgitation
  3. Cerebrovascular Accident
  4. Renal Failure
  5. Arrhythmia
  6. Iron Deficiency Anemia

IX. References

  1. Saenz (1999) Am Fam Physician 59(7):1857-66 [PubMed]
  2. Cyran (1998) PREP review lecture, October, Phoenix
  3. Merenstein (1994) Pediatrics, Lange

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