Definition (NCI_NCI-GLOSS)
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A drug used to lessen inflammation and lower the body's immune response. It is used with other drugs to treat leukemia and lymphoma and other types of cancer. It is also used alone or with other drugs to prevent or treat many other conditions. These include conditions related to cancer, such as anemia (a low level of red blood cells), allergic reactions, and loss of appetite. Prednisone is a type of therapeutic glucocorticoid.
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Definition (NCI)
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A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.
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Definition (MSH)
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A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
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Definition (CSP)
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synthetic anti-inflammatory glucocorticoid derived from cortisone; biologically inert and converted to prednisolone in the liver.
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Definition (PDQ)
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A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42487&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42487&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C770" NCI Thesaurus)
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Concepts |
Pharmacologic Substance
(T121)
, Hormone
(T125)
, Steroid
(T110)
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MSH |
D011241
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SnomedCT |
116602009, 10312003 |
LNC |
LP18109-6, MTHU003245 |
English |
Dehydrocortisone, delta-Cortisone, Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-, 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione, Deltadehydrocortisone, 1;2-Dehydrocortisone, Delta(1)-Cortisone, Deltacortisone, Prednisonum, Metacortandracin, prednisone, prednisone (medication), PREDNISONE, 1,2-Dehydrocortisone, Prednisone [Chemical/Ingredient], Delta 1-Cortisone, predniSONE, .delta.1-Cortisone, 1, 2-Dehydrocortisone, Deltacortisone preparation, Deltadehydrocortisone preparation, Prednisone preparation, Prednisone (substance), Prednisone preparation (product), PRD, Prednisone, Prednisone preparation (substance), PRED, PredniSONE |
Swedish |
Prednison
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Czech |
prednison
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Finnish |
Prednisoni
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Russian |
PREDNIZON, DEL'TA-KORTIZON, DEGIDROKORTIZON, ДЕГИДРОКОРТИЗОН, ДЕЛЬТА-КОРТИЗОН, ПРЕДНИЗОН |
Spanish |
deltacortisona, prednisona (producto), preparado con prednisona (producto), preparado con deltacortisona, deltadehidrocortisona, preparado con deltadehidrocortisona, preparado con prednisona, prednisona (sustancia), prednisona, preparado de deltacortisona, preparado de deltadehidrocortisona, preparado de prednisona (producto), preparado de prednisona (sustancia), preparado de prednisona, delta Cortisona, Deshidrocortisona, Prednisona |
Italian |
Deidrocortisone, delta-Cortisone, Prednisone |
Croatian |
PREDNIZON
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Polish |
Prednizon, Encorton |
Japanese |
デヒドロコルチゾン, プレドニソン, プレドニゾン |
French |
Prednisone
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German |
Dehydrocortison, Prednison, Delta-Cortison |
Portuguese |
delta-Cortisona, Desidrocortisona, Prednisona |