II. Category: Class A (No risk in controlled human studies)

  1. Dessicated Thyroid (Armour Thyroid)
  2. Levothyroxine (T4 or Synthroid)
  3. Liothyronine (T3 or Cytomel)

III. Category: Class B (No risk in controlled animal studies)

IV. Category: Class C (Small risk in controlled animal studies)

  1. Acetohexamide
  2. Beclomethasone
  3. Betamethasone
  4. Bromocriptine
  5. Chlorpropamide (Diabinase)
  6. Dexamethasone
  7. Glipizide (Glucotrol)
  8. Glyburide (Micronase or DiaBeta)
  9. Triamcinolone

V. Category: Class D (Strong evidence of risk to the human fetus)

VI. Category: Class X (Very high risk to the human fetus)

  1. Clomiphene (Clomid)
  2. Danazol
  3. Diethylstilbesterol (DES)
  4. Estrogens (all)
  5. Iodide I-131
  6. Leuprolide (Leupron)
  7. Norethindrone
  8. Norethynodrel
  9. Norgestrel
  10. Oral Contraceptives

VII. References

  1. Briggs (1998) Drugs in Pregnancy and Lactation, 5th ed
  2. Larimore (2000) Prim Care 27(1):35-53 [PubMed]

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