II. Indications
- Medical Uses
- Used to enhance growth in Short Stature
- Illicit uses
- Ergogenic Aid used by athletes
- Similar effect as with Anabolic Steroids
- Difficult to detect
- Expensive (>$1000/month)
III. Preparations
- Initially derived from cadavers in 1950's
- Transmitted Creutzfeldt-Jakob Disease to patients
- Now produced by recombinant Genetics
IV. Dosing
- Available only via injection
V. Adverse Effects
- Growth-Hormone induced Myopathy
- Muscles hypertrophy, but are weaker than before
- Acromegaly
- Diabetes Mellitus
- Cardiomyopathy
- Congestive Heart Failure
- May be related to Leukemia development
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Related Studies
Concepts | Pharmacologic Substance (T121) , Hormone (T125) , Amino Acid, Peptide, or Protein (T116) |
MSH | D019382 |
SnomedCT | 395883003, 325831003, 325892008, 129495007 |
English | Biosynthetic human growth horm, HGH - Growth hormone, Somatropin, somatropin, Somatotrophin, Human growth hormone, GH - Growth hormone, Somatotropic hormone, Growth hormone, SOMATROPIN, Somatropin [2] (product), Somatropin [2], Biosynthetic human growth hormone, Somatropin (product), Somatropin (substance), Somatropin [2] (substance) |
Spanish | hormona de crecimiento, somatotrofina, hormona somatotrófica, somatropina (2), somatropina (2) (producto), somatropina (producto), somatropina (sustancia), somatropina |
Czech | somatropin (lidský), lidský růstový hormon, somatotropin (lidský) |
Finnish | Ihmisen kasvuhormoni |
French | Somatotropine humaine, Somatropine humaine, Hormone de croissance humaine, hGH (Human Growth Hormone) |
Italian | Somatotropina (umana), Somatropina (umana), Somatropina, Ormone della crescita umano, hGH (ormone della crescita umano) |
Russian | GORMON ROSTA CHELOVEKA, ROSTA GORMON METIONILOVYI CHELOVEKA, SOMATOTROPIN CHELOVEKA, SOMATROPIN, ROSTA GORMON CHELOVEKA, METIONILOVYI GORMON ROSTA CHELOVEKA, SOMATREM, ГОРМОН РОСТА ЧЕЛОВЕКА, МЕТИОНИЛОВЫЙ ГОРМОН РОСТА ЧЕЛОВЕКА, РОСТА ГОРМОН МЕТИОНИЛОВЫЙ ЧЕЛОВЕКА, СОМАТОТРОПИН ЧЕЛОВЕКА, СОМАТРЕМ, СОМАТРОПИН |
Japanese | ソマトトロピン(ヒト), ソマトトロピン-ヒト, ヒト成長ホルモン, ソマトロピン, 成長ホルモン-ヒト |
Croatian | HORMON RASTA, HUMANI, HUMANI HORMON RASTA |
Polish | Ludzki hormon wzrostu, Somatropina, HGH, Somatotropina (ludzka) |
Norwegian | Veksthormon, humant, Humant veksthormon, Somatropin (humant), hGH (human veksthormon), Somatropin |
German | Humanes Wachstumshormon, Somatotropin (humanes), Somatropin, HGH (Humanes Wachstumshormon), Somatropin (humanes) |
Portuguese | Somatotropina (Humana), Somatropina (Humana), Hormônio do Crescimento Humano |
Ontology: Recombinant Human Growth Hormone (C0384570)
Definition (MSH) | Mammalian-cell derived recombinant human growth hormone. |
Definition (PDQ) | A recombinant form of endogenous human growth hormone (GH), a polypeptide produced by the anterior lobe of the human pituitary gland. GH exhibits growth-promoting effects and metabolic effects on carbohydrate, fat, protein and bone metabolism. GH stimulates protein synthesis and the uptake of amino acids into cells, and induces lipolysis in adipose tissues. The secretion of GH increases with sexual maturation and then declines steadily. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=456264&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=456264&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C837" NCI Thesaurus) |
Concepts | Hormone (T125) , Amino Acid, Peptide, or Protein (T116) , Pharmacologic Substance (T121) |
MSH | D019382 |
SnomedCT | 31696009, 126193008 |
English | r-hGH(m), rhGH, recombinant human growth hormone, Recombinant Human Growth Hormones, Recombinant Human Growth Hormones [Chemical/Ingredient], Recombinant Human Growth Hormone, hghr, hGHr, Human growth hormone recombinant, Human growth hormone recombinant (product), r-hGH-M, Human growth hormone recombinant preparation (product), Human growth hormone recombinant preparation, Human growth hormone recombinant (substance), Human growth hormone recombinant preparation (substance), Recombinant Human Growth Hormone (Mammalian) |
German | Rekombinantes humanes Wachstumshormon (Säugetiere), r-hGH(m), r-hGH-M |
Italian | r-hGH(m), r-hGH-M, Ormone della crescita umano ricombinante (mammiferi) |
Norwegian | r-hGH(m), Rekombinant humant veksthormon (pattedyr-), r-hGH-M |
Spanish | somatotropina humana biotecnológica (producto), somatotropina humana biotecnológica, STH recombinante, somatotrofina humana recombinante, preparado de somatotrofina humana biotecnológica, preparado de somatotropina humana biotecnológica (producto), preparado de somatotropina humana biotecnológica (sustancia), preparado de somatotropina humana biotecnológica, somatotropina humana biotecnológica (sustancia) |