II. Medications: Hormone Analogs

  1. Background
    1. Naturally occurring Hormones or their derivatives
  2. Corticosteroids (lymphoid malignancy)
    1. Short-acting (e.g. Hydrocortisone)
    2. Intermediate-acting (e.g. Prednisone, Methylprednisolone)
    3. Long-acting (e.g. Dexamethasone)
  3. Somatostatin Analogs (GI neuroendocrine tumors, Carcinoid Syndrome, Merkel Cell carcinoma)
    1. Octreotide (Sandostatin)
    2. Lanreotide (Somatuline)
  4. Progestins
    1. Megestrol acetate
    2. Medroxyprogesterone acetate
  5. Conjugates (novel, hormonal agents conjugated to a cytotoxic agent)
    1. Estramustine (EmCyt)
      1. Estrogen conjugated to an alkylkating agent
      2. Selective accumulation of alkylating cytotoxic effects in Estrogen receptor positive tumor cells
      3. Used in Prostate Cancer
  6. Other Uncommonly used (or historically used) hormonal Chemotherapy agents
    1. Androgens (Historical use in Breast Cancer)
      1. Fluoxymesterone
      2. Danazol
    2. Estrogens (Uncommon use in Prostate Cancer)
      1. Diethylstilbesterol

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Related Studies

Ontology: Antineoplastic Agents, Hormonal (C0282559)

Definition (MSH) Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)
Concepts Pharmacologic Substance (T121)
MSH D018931
English Agents, Antineoplastic Hormonal, Antineoplastic Agents, Hormonal, Antineoplastic Drugs, Hormonal, Antineoplastic Hormonal Agents, Antineoplastic Hormonal Drugs, Antineoplastics, Hormonal, Drugs, Antineoplastic Hormonal, Hormonal Agents, Antineoplastic, Hormonal Antineoplastic Agents, Hormonal Antineoplastic Drugs, Hormonal Antineoplastics, Hormonal Drugs, Antineoplastic, HORMONAL ANTINEOPL DRUGS, ANTINEOPL HORMONAL AGENTS, HORMONAL ANTINEOPL, HORMONAL AGENTS ANTINEOPL, ANTINEOPL HORMONAL, ANTINEOPL DRUGS HORMONAL, ANTINEOPL HORMONAL DRUGS, HORMONAL ANTINEOPL AGENTS, ANTINEOPL AGENTS HORMONAL
French Antinéoplasique hormonal, Antinéoplasiques hormonaux
Swedish Cellgifter, hormonella
Czech antitumorózní látky hormonální
Finnish Hormonaaliset solunsalpaajat
Italian Farmaci antineoplastici ormonali, Antineoplastici ormonali
Russian PROTIVOOPUKHOLEVYE SREDSTVA GORMONAL'NYE, GORMONAL'NYE PROTIVOOPUKHOLEVYE SREDSTVA, ГОРМОНАЛЬНЫЕ ПРОТИВООПУХОЛЕВЫЕ СРЕДСТВА, ПРОТИВООПУХОЛЕВЫЕ СРЕДСТВА ГОРМОНАЛЬНЫЕ
Croatian ANTITUMORSKA SREDSTVA, HORMONALNA
Polish Leki przeciwnowotworowe hormonalne
Japanese 抗癌剤-ホルモン性, ホルモン性抗腫瘍剤, ホルモン性抗腫瘍薬, 抗腫瘍剤-ホルモン性, ホルモン性抗癌剤
Portuguese Agentes Antineoplásicos Hormonais, Antineoplásicos Hormonais
Spanish Antineoplásicos Hormonales, Agentes Antineoplásicos Hormonales, Agentes Hormonales Antineoplásicos
German Antineoplastika, hormonelle, Hormonelle Antineoplastika

Ontology: Cancer hormonal therapy (C0877050)

Concepts Therapeutic or Preventive Procedure (T061)
Italian Terapia ormonale tumorale
Japanese ガンホルモンリョウホウ, 癌ホルモン療法
Czech Hormonální léčba rmaligního nádorovéo onemocnění
English cancers hormonal therapy, cancer hormonal therapy, hormonal therapy cancer, Cancer hormonal therapy
Spanish Hormonoterapia contra el cáncer
Hungarian Rák hormonkezelés
Portuguese Terapia hormonal cancerosa
Dutch hormonale kankertherapie
French Traitement hormonal anticancéreux
German hormonelle Krebstherapie