Definition (NCI_NCI-GLOSS)
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A drug used to treat skin problems caused by cutaneous T-cell lymphoma that have not gotten better after other treatment. It is also being studied in the treatment of other types of cancer. Bexarotene is a type of retinoid.
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Definition (NCI)
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A synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression. (NCI04)
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Definition (PDQ)
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A synthetic retinoic acid agent with potential antineoplastic, chemopreventive, teratogenic and embryotoxic properties. Bexarotene selectively binds to and activates retinoid X receptors (RXRs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell proliferation, apoptosis of some cancer cell types, and tumor regression. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42117&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=42117&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1635" NCI Thesaurus)
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Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
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MSH |
C095105
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SnomedCT |
395281006, 116346006, 387023000 |
English |
4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl)benzoic acid, 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic Acid, 3-methyl TTNEB, 3-methyl-TTNEB, retinoids bexarotene, bexarotene (medication), bexarotene, bexarotene [Chemical/Ingredient], BEXAROTENE, Bexarotene (product), Bexarotene (substance), Bexarotene |
Spanish |
bexarronteno, bexaroteno, bexaronteno (sustancia), bexaronteno, bexaroteno (sustancia), bexaroteno (producto), bexarronteno (producto), bexarronteno (sustancia) |