Definition (NCI_NCI-GLOSS)
|
A substance that causes blood stem cells (cells from which other types of cells develop) to change into different types of blood cells and increases the number and actions of these cells in the blood. Kit ligand is a type of cytokine and a type of growth factor.
|
Definition (NCI)
|
Stem Cell Factor is a hematopoietic growth factor, a key signal in mast cell differentiation and function, and a ligand for the KIT tyrosine kinase receptor CD117. In the mouse, this growth factor is encoded by Sl ('steel'), a gene critical to the development of several cell lineages as well as to hematopoiesis in the adult. SCF augments proliferation of myeloid and lymphoid progenitors. (from OMIM 184745 and NCI)
|
Definition (CSP)
|
expressed during embryogenesis and provides key signal in multiple aspects of mast cell differentiation and function; hematopoietic growth factor and ligand of c-kit receptor CD117.
|
Definition (MSH)
|
A hematopoietic growth factor and the ligand of the cell surface c-kit protein (PROTO-ONCOGENE PROTEINS C-KIT). It is expressed during embryogenesis and is a growth factor for a number of cell types including the MAST CELLS and the MELANOCYTES in addition to the HEMATOPOIETIC STEM CELLS.
|
Concepts |
Biologically Active Substance
(T123)
, Amino Acid, Peptide, or Protein
(T116)
|
MSH |
D019089
|
SnomedCT |
58613001
|
English |
mast cell growth factor, Mast Cell Growth Factor, Steel Factor, Stem Cell Factor, c kit Ligand, c-kit Ligand, kit Ligand, Stem Cell Factor [Chemical/Ingredient], scf, stem cell factor (SCF), Kit ligand, stem cell factor, kit ligand, MCGF, Mast cell growth factor, SCF, KITLG, Kit Ligand, MGF Stem Cell Factor, MGF, C-Kit Ligand |
German |
Mastzellen-Wachstumsfaktor, C-Kit-Ligand, C-kit Ligand, Stammzell-Faktor, Steel-Faktor, Steel Factor, Stammzellen-Faktor, Stammzellfaktor, Mastzellenwachstumsfaktor, Stammzellenfaktor |
Swedish |
Stemcellsfaktor
|
Czech |
faktor růstu kmenových buněk
|
Portuguese |
Fator de Células-Tronco, Fator de Crescimento do Mastócitos, Fator de Célula-Tronco, Fator de Crescimento do Mastócito, Fator de Steel, Ligante c-kit |
Spanish |
Factor de Células Madre, Factor de Crecimiento de Mastocitos, Factor de Célula Madre, Factor de Acero, Factor de Crecimiento de Mastocito, Ligando c-kit |
Finnish |
Kantasolutekijä
|
French |
Facteur de cellule souche, Facteur de croissance du mastocyte, Ligand kit, Facteur de croissance SCF, Facteur de croissance mastocytaire, Facteur des cellules souches, Ligand de c-kit, Facteur steel, Ligand de kit, Ligand c-kit |
Russian |
FAKTOR ROSTA STVOLOVYKH KLETOK KROVI, STVOLOVYKH KLETOK KROVI FAKTOR ROSTA, TUCHNYKH KLETOK FAKTOR ROSTA, СТВОЛОВЫХ КЛЕТОК КРОВИ ФАКТОР РОСТА, ТУЧНЫХ КЛЕТОК ФАКТОР РОСТА, ФАКТОР РОСТА СТВОЛОВЫХ КЛЕТОК КРОВИ |
Italian |
Steel factor, Fattore di crescita delle mast-cellule, Ligando c-kit, Ligando kit, Fattore della cellula staminale |
Polish |
Czynnik wzrostu komórek pnia, SCF, Czynnik wzrostu komórek macierzystych |
Japanese |
幹細胞因子, c-Kitリガンド, スチール因子, 肥満細胞成長因子, c-kitリガンド |