Exert cytotoxic effects via transfer of alkyl group
DNA alkylation (key to cellular lethality)
Chemically react with many cellular constituents
DNA cross linking is a primary role of agents
Replicating cells are most susceptible to agents
Alkylating Agents are not cell cycle specific
Bis (chloroethyl) amines
Other drugs causing alkylation
Images: Related links to external sites (from Bing)
These images are a random sampling from a Bing search on the term "Alkylating Agent." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images
FPnotebook.com is a rapid access, point-of-care medical reference for primary care and emergency clinicians. Started in 1995, this collection now contains 6760 interlinked topic pages divided into a tree of 31 specialty books and 732 chapters. Content is updated monthly with systematic literature reviews and conferences.
Although access to this website is not restricted, the information found here is intended for use by medical providers. Patients should address specific medical concerns with their physicians.
This page was written by Scott Moses, MD, last revised on 10/21/2007 and last published on 3/9/2020.