Medication Causes of Dyspepsia

Aka: Medication Causes of Dyspepsia, Gastric Irritant, Irritant Gastritis

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II. Causes: Gastric Irritants (risks for Peptic Ulcer Disease)

  1. Aspirin
  2. NSAIDS (including COX2 Inhibitors)
    1. See NSAID Gastrointestinal Adverse Effects
  3. Alcohol
  4. Coffee and other Caffeine sources
  5. Tobacco Abuse
  6. Corticosteroids (e.g. Prednisone)

III. Causes: Herbal preparations causing Dyspepsia

  1. Garlic
  2. Gingko
  3. Saw Palmetto
  4. Feverfew
  5. Chaste Tree Berry
  6. White willow bark

IV. Causes: Medications causing Dyspepsia

  1. Antiinflammatory medications
    1. Aspirin
    2. NSAIDs
    3. COX2 Inhibitors
  2. Bisphosphonates
    1. Alendronate (Fosamax)
    2. Risedronate (Actonel)
  3. Cisapride (Propulsid)
  4. Codeine
  5. Corticosteroids (Prednisone)
  6. Oral Hypoglycemic Agents
    1. Alpha-Glucosidase Inhibitor such as Acarbose (Precose) or Miglitol (Glyset)
    2. Metformin (Glucophage)
  7. Erythromycin
  8. Iron
  9. Opioids
  10. Orlistat (Xenical)
  11. Potassium chloride
  12. Theophylline

V. References

  1. Feldman (1998) Sleisenger and Fordtran's GI, p. 106-8
  2. Bazaldua (1999) Am Fam Physician 60(6): 1773-88 [PubMed]

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