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Definition (NCI)
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A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04)
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Definition (NCI_NCI-GLOSS)
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A drug used to prevent or reduce nausea and vomiting. It belongs to the family of drugs called antiemetics.
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Definition (MSH)
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A phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
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Definition (CSP)
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phenothiazine derivative used chiefly as an antiemetic.
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Definition (PDQ)
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A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39564&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C774" NCI Thesaurus)
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| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
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| MSH |
D011346
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| SnomedCT |
322128008, 321493000, 372853006, 79129001 |
| LNC |
LP102316-9, MTHU036745 |
| English |
Prochlorperazine, 10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-, Prochlorperazine [antipsych], Prochlorperazine [antipsych] [see dhe..], Prochlorperazine [nausea], 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine, prochlorperazine (medication), PROCHLORPERAZINE, Prochlorperazine [Chemical/Ingredient], Prochlorperazine [nausea] (product), Prochlorperazine [antipsych] [see dhe..] (product), prochlorperazine, Prochlorperazine (product), Prochlorperazine (substance), PCPZ, Prochlorperazine [antipsych] [see dhe..] (substance), Prochlorperazine [nausea] (substance) |
| Swedish |
Proklorperazin
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| Czech |
prochlorperazin
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| Finnish |
Proklooriperatsiini
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| Russian |
PROKHLORPERAZIN, ПРОХЛОРПЕРАЗИН |
| Japanese |
プロクロルペラジン
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| Spanish |
proclorperacina (producto), proclorperazina, proclorperazina (producto), proclorperazina [antipsicótico] [véase dhe...], proclorperazina [náuseas], proclorperazina [antipsicótico] [véase dhe...] (producto), proclorperazina [náuseas] (producto), proclorperacina (sustancia), proclorperacina, Proclorperazina |
| Polish |
Prochlorperazyna
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| French |
Prochlorpérazine
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| German |
Prochlorperazin
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| Italian |
Procloroperazina
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| Portuguese |
Proclorperazina
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