Simethicone

Aka: Simethicone, Gas-X, Mylicon, Phazyme

II. Indications

  1. Eructation
  2. Flatulence

III. Dose

  1. Adults: 40-125 mg po qid
  2. Infants: 0.3 ml PO qid prn

IV. Pharmacokinetics

  1. Not absorbed

V. Efficacy

  1. Several controlled clinical trials have been performed
  2. No evidence that Simethicone is better than Placebo

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Related Studies

Cost: Medications

simethicone (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing)
SIMETHICONE 125 MG TAB CHEW Generic OTC $0.06 each
SIMETHICONE 180 MG SOFTGEL Generic OTC $0.05 each
SIMETHICONE 40 MG/0.6 ML DROP Generic OTC $0.07 per ml
SIMETHICONE 80 MG TAB CHEW Generic OTC $0.02 each
gas-x (on 9/21/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
GAS-X EX-STR 125 MG TAB CHEW Generic OTC $0.06 each
GAS-X EXTRA STRENGTH SOFTGEL Generic OTC $0.08 each
GAS-X TABLET CHEWABLE Generic OTC $0.02 each
GAS-X ULTRA STRENGTH SOFTGEL Generic OTC $0.05 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Ontology: Simethicone (C0037138)

Definition (MSH) A poly(dimethylsiloxane) which is a polymer of 200-350 units of dimethylsiloxane, along with added silica gel. It is used as an antiflatulent, surfactant, and ointment base.
Definition (NCI) A mixture of polydimethylsiloxanes with antifoaming and anti-bloating effects. Simethicone reduces the surface tension of gas bubbles causing them to coalesce into larger bubbles that can be passed more easily by belching or flatulence.
Concepts Pharmacologic Substance (T121) , Biomedical or Dental Material (T122) , Organic Chemical (T109)
MSH D012841
SnomedCT 387442005, 77898008
LNC LP171639-0
English Simeticone, Simethicone, simethicone (medication), Simethicone [Chemical/Ingredient], dimethicone activated, activated dimethicone, simethicone, Activated dimethicone, Activated methylpolysiloxane, Simethicone (product), Simethicone (substance), SIMETHICONE
Swedish Simetikon
Czech simethikon
Finnish Simetikoni
Russian SIMETIKON, DIMETIKON, ДИМЕТИКОН, СИМЕТИКОН
Japanese シメチコン
Spanish dimeticona, dimeticona activada, metilpolisiloxano activado, simeticona (producto), simeticona (sustancia), simeticona, Simeticona
Polish Simeticon, Simetykon
Norwegian Simetikon
French Siméticone
German Simethicon
Italian Simeticone
Portuguese Simeticone
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Mylicon (C0721886)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
English Mylicon, mylicon
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Phazyme (C0722576)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
English Phazyme, phazyme
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Pharmacology

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