II. Indications

III. Dosing

  1. Hydrocortisone Rectal Foam 10% (Cortifoam)
    1. Affects the distal left colon and Rectum (last 15 to 20 cm)
    2. Use 1 applicator (90 mg) once to twice daily for 2 to 3 weeks
    3. May extend to use 1 applicator (90 mg) every other day until remission
  2. Hydrocortisone Rectal Suspension for Enema 100 mg/60 ml (Colocort, Cortenema)
    1. Affects the entire left or descending colon
    2. Use one enema (100 mg) each evening for 3 weeks until remission
    3. Preferred over rectal foam if patient able to tolerate

V. References

  1. (2022) Treatment of Mild to Moderate Ulcerative Colitis, Presc Lett, #350406
  2. (2023) Drugs for Inflammatory Bowel Disease, Med Lett Drug Ther 65: 105-12

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Related Studies

Cost: Medications

cortifoam (on 3/15/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
CORTIFOAM 10% AEROSOL $26.45 per gram

Ontology: Hydrocortisone Rectal Product (C0360584)

Concepts Clinical Drug (T200)
SnomedCT 317677009, 350441007
English Rectal hydrocortisone, Rectal hydrocortisone preps, hydrocortisone rectal, hydrocortisones rectal, rectal hydrocortisone preparations, Hydrocortisone, Rectal, Hydrocortisone Rectal Product, Rectal hydrocortisone (product), Rectal hydrocortisone preparations, Rectal hydrocortisone preparations (product), Rectal hydrocortisone (substance), Rectal hydrocortisone preparations (substance)
Spanish hidrocortisona de aplicaciĆ³n rectal (producto), hidrocortisona de aplicaciĆ³n rectal, hidrocortisona, preparaciones rectales (producto), hidrocortisona, preparaciones rectales, preparado rectal con hidrocortisona (producto), preparado rectal con hidrocortisona

Ontology: hydrocortisone acetate 100 MG/ML Rectal Foam (C0977618)

Concepts Clinical Drug (T200)
SnomedCT 317681009
English Hydrocortisone 10% rectal foam, hydrocortisone topical 10% rectal foam, HYDROCORTISONE ACETATE 10% RTL FOAM, Hydrocortisone Acetate Rectal Foam 90 MG/DOSE, HYDROCORTISONE ACETATE 10% FOAM,RTL [VA Product], Hydrocortisone 10% Rectal foam, HYDROCORTISONE ACETATE 10 % RECTAL AEROSOL, FOAM WITH APPLICATOR (GRAM), HYDROCORTISONE ACETATE@10 %@RECTAL@AEROSOL, FOAM WITH APPLICATOR (GRAM), Hydrocortisone Acetate 10% Rectal Foam, hydrocortisone 10% rectal foam with applicator, hydrocortisone acetate 10 % Rectal Foam, HYDROCORTISONE ACETATE 10 % RECTAL AEROSOL, FOAM WITH APPLICATOR (GM), HYDROCORTISONE ACETATE 10% RECTAL AEROSOL, FOAM WITH APPLICATOR (GM), hydrocortisone acetate 100 MG/ML Rectal Foam, HYDROCORTISONE ACETATE 10% FOAM (GM), HYDROCORTISONE ACETATE 10 %WW TOPICAL AEROSOL, FOAM, HYDROCORTISONE ACETATE@10%@RECTAL@FOAM (GM), HYDROCORTISONE ACETATE@10%@RECTAL@AEROSOL, FOAM WITH APPLICATOR (GM), HYDROCORTISONE ACETATE 10% RECTAL FOAM (GM), HYDROCORTISONE ACETATE 10% Rectal (systemic) foam, HYDROCORTISONE ACETATE@10 %@RECTAL@AEROSOL, FOAM WITH APPLICATOR (GM), HYDROCORTISONE ACETATE @ 10% @ FOAM (GM), Hydrocortisone Acetate Rectal Foam 100 MG/GM, Hydrocortisone acetate 10% rectal foam, Hydrocortisone acetate 10% rectal foam (product), Hydrocortisone acetate 10% rectal foam (substance), HYDROCORTISONE ACETATE 10% FOAM,RTL
Spanish acetato de hidrocortisona 10%, espuma rectal (producto), acetato de hidrocortisona 10%, espuma rectal

Ontology: Hydrocortisone Enema (C1246471)

Concepts Clinical Drug (T200)
English Hydrocortisone Enema, enemas hydrocortisone, hydrocortisone enema