Medications that Delay Gastric Emptying

Aka: Medications that Delay Gastric Emptying, Drug-Induced Gastroparesis, Delayed Gastric Emptying due to Medications

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II. Causes: Gastrointestinal Agents

  1. Aluminum hydroxide Antacids
  2. H2 Receptor Antagonists (e.g. Ranitidine)
  3. Proton Pump Inhibitors (e.g. Omeprazole)
  4. Sucralfate
  5. Ondansetron (Zofran)
  6. Phenothiazines (e.g. Chlorpromazine, Promethazine)

III. Causes: Anticholinergic Medications

  1. See Anticholinergic Medications
  2. Diphenhydramine (Benadryl)
  3. Tricyclic Antidepressants
  4. Oxybutynin

IV. Causes: Cardiovascular Medications

  1. Beta-Adrenergic ReceptorAgonists
  2. Calcium Channel Blockers

V. Causes: Diabetes Medications

  1. Incretin Mimetics or GLP-1 Agonists (e.g. Exenatide, Liraglutide )
  2. Pramlintide (Symlin)

VI. Causes: Miscellaneous

  1. Alcohol
  2. Opioid Analgesics
  3. Interferon alfa
  4. Levodopa
  5. Cyclosporine (Sandimmune)
  6. Lithium

VII. References

  1. (2013) Prescr Lett 20(6):34
  2. Careyva (2016) Am Fam Physician 94(12): 980-6 [PubMed]

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