Glyceryl trinitrate

Aka: Glyceryl trinitrate

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II. Indication

  1. Anal Fissure

III. Mechanism

  1. Reduces maximal anal resting pressure

IV. Dosing

  1. Glyceryl Trinitrate ointment 0.2% bid for 6 weeks

V. Efficacy

  1. Study of 80 patients with Anal Fissures
    1. At 8 weeks, fissures healed in 68% versus 8% Placebo
  2. References
    1. Lund (1997) Lancet 349-11-4 [PubMed]

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