II. Indications (Purported uses)
- Migraine Headache prevention
III. Efficacy
- Some studies support benefit for Migraine prevention
- No benefit in Rheumatoid Arthritis
IV. Mechanism
- Inhibits Prostaglandin synthesis
- Serotonin Antagonist
- Inhibits Platelet aggregation
V. Dosing
- Standard extract 125 mg (at least 0.2% parthenolide)
VI. Adverse Effects
VII. Contraindications
- Pregnancy
- Feverfew may induce Menstruation
- Concurrent Anticoagulant use or peri-operative
- Feverfew increases bleeding risk
VIII. References
- Shaughnessy (1997) Fam Practice Recert 19(10):53-6
- Zink (1998) Am Fam Physician 58(5): 1133-40 [PubMed]
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| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| English | Feverfew Extract, feverfew extract, feverfew (medication), Tanacetum Parthenium, Feverfew, TANACETUM PARTHENIUM, feverfew, FEVERFEW, Tanacetum parthenium extract, FEVERFEW EXTRACT |
