II. Indications
- See NSAID
- FDA approved indications in Adults
- FDA approved indications in children
III. Contraindications
- See NSAID
IV. Mechanism
V. Medications
- Meloxicam tablets 7.5 mg, 15 mg
- Meloxicam capsules 5 mg, 10 mg
- Meloxicam suspension 1.5 mg/ml
- Shake suspension well before use
VI. Dosing: Adults
-
Arthritis (OA, RA)
- Meloxicam 7.5 mg orally daily
- May advance to a maximum of 15 mg orally daily
VII. Dosing: Child
-
Juvenile Rheumatoid Arthritis (age >=2 years old)
- Meloxicam 0.125 mg/kg orally daily (up to maximum of 7.5 mg/day)
VIII. Adverse Effects
- See NSAID
- Despite being touted as more COX-2 specific, still has moderate gastrointestinal adverse effects
IX. Safety
X. Resources
Images: Related links to external sites (from Bing)
Related Studies
| meloxicam (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| MELOXICAM 15 MG TABLET | Generic | $0.02 each |
| MELOXICAM 7.5 MG TABLET | Generic | $0.02 each |
| mobic (on 1/10/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| MOBIC 7.5 MG TABLET | Generic | $0.02 each |
Ontology: meloxicam (C0083381)
| Definition (NCI) | An oxicam derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of meloxicam. |
| Definition (PDQ) | An oxicam derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Unlike traditional nonselective NSAIDs, meloxicam preferentially inhibits the activity of cyclo-oxygenase II (COX-II), resulting in a decreased conversion of arachidonic acid into prostaglandin precursors. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of meloxicam. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=472195&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=472195&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C61439" NCI Thesaurus) |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | C065757 |
| SnomedCT | 363594002, 125694008, 387055000 |
| English | meloxicam, miloxicam, 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, meloxicam (medication), MELOXICAM, meloxicam [Chemical/Ingredient], reumoxicam, Meloxicam product (substance), Meloxicam product, Meloxicam, Meloxicam (product), Meloxicam (substance) |
| Spanish | meloxicam (producto), meloxicam (sustancia), meloxicam |
