II. Indications
- See NSAID
- FDA approved indications
III. Contraindications
- See NSAID
- Avoid in Renal Insufficiency
IV. Mechanism
V. Medications
- Fenoprofen capsules or tablets: 200 mg, 400 mg, 600 mg
VI. Dosing
- Fenoprofen (Nalfon)
- Arthritis (OA/RA): 300 to 600 mg orally three to four times daily (max: 3200 mg/day)
- Mild to moderate pain: 200 mg every 4 to 6 hours
VII. Adverse Effects
VIII. Safety
IX. Efficacy
- Similar to Aspirin (but more potent)
X. Resources
Images: Related links to external sites (from Bing)
Related Studies
| Definition (NCI) | A propionic acid derivative with analgesic, non-steroidal antiinflammatory and antirheumatic properties. Fenoprofen inhibits both isozymes of cyclooxygenase; resulting in prostaglandin synthesis inhibition, thereby blocking the conversion of arachidonic acid to prostaglandins. In addition, fenoprofen activates both peroxisome proliferator activated receptors (PPAR)-alpha and -gamma, by which it may down-regulate leukotriene B4 production. |
| Definition (MSH) | An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to ASPIRIN, but causes less gastrointestinal bleeding. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | D005279 |
| SnomedCT | 363602002, 322292009, 329638000, 373525006, 71798005 |
| LNC | LP16146-0, MTHU016792 |
| English | Fenoprofen, Benzeneacetic acid, alpha-methyl-3-phenoxy-, (+-)-, Fenoprofen [analgesic], Fenoprofen [musc skel], Fenoprofen [musculoskeletal use], Fenoprofen [Chemical/Ingredient], Fenoprofen product (substance), Fenoprofen [analgesic] (product), Fenoprofen product, Fenoprofen [musculoskeletal use] (product), FENOPROFEN, fenoprofen, Fenoprofen (product), Fenoprofen (substance), Fenoprofen [analgesic] (substance), Fenoprofen [musculoskeletal use] (substance) |
| Swedish | Fenoprofen |
| Czech | fenoprofen |
| Finnish | Fenoprofeeni |
| Russian | FENOPROFEN, ФЕНОПРОФЕН |
| Japanese | フェノプロフェン |
| Polish | Fenoprofen |
| Spanish | fenoprofeno [analgésico], fenoprofeno, producto, fenoprofeno, producto (sustancia), fenoprofeno [analgésico] (producto), fenoprofeno [uso musculoesquelético] (producto), fenoprofeno [uso musculoesquelético], fenoprofeno (producto), fenoprofeno (sustancia), fenoprofeno, Fenoprofeno |
| French | Fénoprofène |
| German | Fenoprofen |
| Italian | Fenoprofene |
| Portuguese | Fenoprofeno |
