II. Epidemiology

  1. Age of onset: 5-8 years old (mean)
  2. Incidence: 700 cases per year in United States

III. Pathophysiology

  1. Roundworm infection (Toxocariasis)
  2. Spreads to eye from concurrent Visceral Larva Migrans

IV. Symptoms

  1. Gradual or sudden unilateral visual loss
  2. Eye discomfort
  3. Symptoms of Visceral Larva Migrans often absent
  4. Strabismus

V. Signs: Slit Lamp Exam

  1. Leukocoria
  2. Endophthalmitis
  3. Choroidal Granuloma (subretinal Granulomatous mass)
  4. Posterior pole Granuloma
  5. Peripheral Granuloma with traction bands

VI. Labs

VII. Differential Diagnosis

  1. Retinoblastoma
  2. Strabismus
  3. Exudative retinitis (Coat's disease)

VIII. Complications

  1. Ocular inflammation with scarring with risk of Vision Loss

IX. Course

  1. Ocular symptoms may present up to 10 years after infection

X. Management

  1. No satisfactory treatment
  2. Trial of Corticosteroids
  3. Surgery may be indicated in severe cases
  4. See Visceral Larva Migrans

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Related Studies

Ontology: Ocular Larva Migrans (C0028848)

Concepts Disease or Syndrome (T047)
MSH D007815
SnomedCT 240866006
English Larva Migrans, Ocular, ocular toxocariasis, ocular larva migrans, larva migrans ocular, toxocariasis ocular, Granulomatous ophthalmitis, Ocular larva migrans, Ocular toxocariasis, Ocular toxocariasis (disorder), Ocular Larva Migrans
French Larva migrans oculaire
German Okuläre Larva migrans, Larva migrans, okuläre
Italian Larva migrans oculare
Czech larva migrans ocularis, oční larva migrans
Spanish larva migra ocular, oftalmitis granulomatosa, toxocariasis ocular (trastorno), toxocariasis ocular, Larva Migrans Ocular
Dutch Larva migrans ocularis, Oculaire larva migrans
Portuguese Larva Migrans Ocular