Definition (NCI_NCI-GLOSS)
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Cancer that forms in the tissues of the retina (the light-sensitive layers of nerve tissue at the back of the eye). Retinoblastoma usually occurs in children younger than 5 years. It may be hereditary or nonhereditary (sporadic).
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Definition (NCI)
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A neuroblastoma arising from the retina.
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Definition (NCI_CDISC)
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A malignant neoplasm originating in the nuclear layer of the retina.
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Definition (NCI)
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A malignant tumor that originates in the nuclear layer of the retina. As the most common primary tumor of the eye in children, retinoblastoma is still relatively uncommon, accounting for only 1% of all malignant tumors in pediatric patients. These tumors may be multifocal, bilateral, congenital, inherited, or acquired. Seventy-five percent of retinoblastomas are unilateral; 60% occur sporadically. A predisposition to retinoblastoma has been associated with 13q14 cytogenetic abnormalities. Patients with the inherited form also appear to be at increased risk for secondary nonocular malignancies such as osteosarcoma, malignant fibrous histiocytoma, and fibrosarcoma.
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Definition (CSP)
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malignant congenital blastoma, occurring in both hereditary and sporadic forms, composed of tumor cells arising from the retinoblasts; the most common tumor of the eye in children.
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Definition (MSH)
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A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
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Concepts |
Neoplastic Process
(T191)
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MSH |
D012175
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ICD10 |
M9510/3
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SnomedCT |
19906005, 189935007, 189934006, 154553002, 134191003, 269614001, 370967009 |
English |
Retinoblastomas, RETINOBLASTOMA, RB - Retinoblastoma, Glioblastoma, Retinal, Glioblastomas, Retinal, Glioma, Retinal, Gliomas, Retinal, Neuroblastoma, Retinal, Neuroblastomas, Retinal, Retinal Glioblastoma, Retinal Glioblastomas, Retinal Glioma, Retinal Gliomas, Retinal Neuroblastomas, Retinoblastoma NOS, [M]Retinoblastoma NOS, [M]Retinoblastomas, Retinoblastoma (M-95103), malignant retinoblastoma of eye (diagnosis), retinoblastoma (diagnosis), retinoblastoma, malignant retinoblastoma of eye, Retinoblastoma [Disease/Finding], Eye Cancer, Retinoblastoma, disorders retinoblastoma, retinoblastomas, [M]Retinoblastomas (morphologic abnormality), [M]Retinoblastoma NOS (morphologic abnormality), RB, RETINOBLASTOMA, MALIGNANT, Retinoblastoma - morphology, Retinoblastoma (disorder), Retinoblastoma (morphologic abnormality), Retinoblastoma, NOS, Retinoblastoma, Retinal Neuroblastoma, Neuroblastoma of Retina, Neuroblastoma of the Retina |
French |
RETINOBLASTOME, Rétinoblastome SAI, Rétinoblastome, Rétinoglioblastome, Gliome de la rétine, Gliome rétinien |
Portuguese |
RETINOBLASTOMA, Retinoblastoma NE, Glioblastoma Retiniano, Glioma Retiniano, Neuroblastoma Retiniano, Retinoblastoma |
Dutch |
retinoblastoom NAO, retinoblastoom, Blastoom, retino-, Glioblastoom, retinaal, Glioom, retinaal, Neuroblastoom, retinaal, Retinoblastoom |
German |
Retinoblastom NNB, Glioblastom, retinales, Gliom, retinales, Glioma retinae, Neuroblastom, retinales, Neuroblastoma retinae, Retinoblastom |
Italian |
Retinoblastoma NAS, Glioma retinico, Retinoblastoma |
Spanish |
Retinoblastoma NEOM, [M]retinoblastoma, SAI (anomalía morfológica), [M]retinoblastoma, SAI, [M]retinoblastomas (anomalía morfológica), [M]retinoblastomas, morfología de retinoblastoma, retinoblastoma (anomalía morfológica), retinoblastoma (trastorno), retinoblastoma, Retinoblastoma, Glioblastoma Retiniano, Glioma Retiniano, Neuroblastoma Retiniano |
Swedish |
Retinoblastom
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Czech |
retinoblastom, Retinoblastom, Retinoblastom NOS |
Finnish |
Retinoblastooma
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Russian |
GLIOBLASTOMA SETCHATKI, NEIROBLASTOMA SETCHATKI, GLIOMA SETCHATKI, RETINOBLASTOMA, ГЛИОБЛАСТОМА СЕТЧАТКИ, ГЛИОМА СЕТЧАТКИ, НЕЙРОБЛАСТОМА СЕТЧАТКИ, РЕТИНОБЛАСТОМА |
Croatian |
RETINOBLASTOM
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Polish |
Siatkówczak, Siatkówczak złośliwy |
Hungarian |
Retinoblastoma k.m.n., Retinoblastoma |
Japanese |
神経膠腫-網膜, 網膜芽細胞腫, 網膜芽細胞腫NOS, モウマクガサイボウシュ, モウマクガサイボウシュNOS, 網膜神経膠腫, 網膜芽腫 |
Norwegian |
Retinoblastom, Retinalt nevroblastom, Retinalt gliom, Netthinneblastom, Retinalt glioblastom |