III. Physiology

  1. See Pupil

IV. Technique

  1. Preparation
    1. Use a bright flashlight
    2. Perform in a semi-dark room (but light enough to see bilateral pupil reaction)
    3. Move the flashlight from directly in front of one eye, to directly in front of the other
      1. Maintain a constant distance between flashlight and eye
      2. Avoid maintaining a central point at nose (stimulates near response)
  2. Check left eye response (direct and consensual)
    1. Shine light on left eye for 3 seconds and check left pupil reflex
    2. Shine light on right eye for 3 seconds and check left pupil reflex
  3. Check right eye response (direct and consensual)
    1. Shine light on right eye for 3 seconds and check right pupil reflex
    2. Shine light on left eye for 3 seconds and check right pupil reflex

V. Findings: Normal response

  1. Direct Light Reflex
    1. Pupil constricts to direct light
  2. Consensual Light Reflex
    1. Pupil constricts to light shining on opposite pupil

VI. Findings: Abnormal - Afferent lesion (RAFD, Marcus Gunn Pupil)

  1. Findings: Relative Afferent Pupillary Defect (RAFD)
    1. No pupil response to direct light
    2. Intact Consensual Light Reflex (when light shone in opposite eye)
      1. Paradoxical Pupil Dilation to direct light
      2. Occurs on moving light from opposite to affected eye (Swinging Flashlight Test)
  2. Causes: Optic Nerve Lesion (rarely at Retina)
    1. Ischemic Optic Neuropathy
    2. Optic Neuritis (e.g. Multiple Sclerosis)
    3. Optic Nerve compression or Trauma
    4. Glaucoma (asymmetric)
    5. Other Optic Neuropathy (e.g. infiltrative, radiation, infectious)
  3. References
    1. Broadway (2012) Community Eye Health 25(79-80):58-9 +PMID: 23520419 [PubMed]

VII. Findings: Abnormal - Efferent lesion (CN 3 or pupillary Muscle)

  1. Affected eye loses consensual and Direct Light Reflex
  2. Unaffected eye maintains consensual and direct reflex

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Related Studies

Ontology: Afferent Pupillary Defect (C0339662)

Concepts Finding (T033)
MSH D011681
SnomedCT 8099001, 232121005
English APD - Afferent pupil defect, Marcus-Gunn pupil, Marcus Gunn pupil (dilates to light), Marcus Gunn pupil (physical finding), the pupils reacted consensually but then dilated in the presence of direct light, Afferent Pupillary Defects, Pupillary Defect, Afferent, Pupillary Defects, Afferent, Marcus Gunn Pupil, Marcus-Gunn Pupil, Pupil, Marcus-Gunn, afferent pupillary defect, marcus gunn pupil, gunn marcus pupils, Marcus-Gunn pupillary sign, Marcus-Gunn pupillary sign (finding), Swinging flashlight sign, Marcus Gunn pupil, APD - Afferent pupillary defect, Afferent pupillary defect, Afferent pupillary defect (disorder), Marcus-Gunn sign, Afferent Pupillary Defect
Dutch Marcus Gunn-pupil, Afferent pupildefect, Marcus-Gunn-pupil
French Pupille de Marcus Gunn, Déficit pupillaire afférent, Pupille de Marcus-Gunn
German Marcus Gunn-Pupille, Afferenter Pupillendefekt, Marcus-Gunn-Pupille
Portuguese Pupila de Marcus Gunn, Defeito Pupilar Aferente, Pupila de Marcus-Gunn
Spanish Pupila de Marcus Gunn, Defecto Pupilar Aferente, signo pupilar de Marcus - Gunn, signo pupilar de Marcus - Gunn (hallazgo), defecto pupilar aferente (trastorno), defecto pupilar aferente, Pupila de Marcus-Gunn
Japanese マーカス・ガン瞳孔, マーカスガンドウコウ
Czech Marcus Gunnova zornice
Hungarian Marcus Gunn pupilla
Norwegian Marcus Gunns pupill, Marcus Gunns fenomen, Marcus Gunns syndrom, Afferent pupilldefekt
Italian Pupilla di Marcus Gunn, Difetto pupillare afferente

Ontology: Pupil reactivity (C0517966)

Concepts Finding (T033)
English Pupil reactivity

Ontology: Absence of direct light pupillary reflex (C0522341)

Concepts Finding (T033)
SnomedCT 103273009
English Absence of direct light pupillary reflex, Absence of light reflex, Loss of light reflex, Absence of direct light pupillary reflex (finding)
Spanish ausencia a la luz directa, ausencia de reflejo pupilar a la luz directa (hallazgo), ausencia de reflejo pupilar a la luz directa, pérdida del reflejo a la luz

Ontology: Pupillary light reflex tests (C0853996)

Concepts Diagnostic Procedure (T060)
Italian Prove del riflesso pupillare alla luce, Prova del riflesso pupillare alla luce
Dutch lichtreflextest pupil, pupil-lichtreflextests
French Tests de réponse pupillaire à la lumière, Tests de réflexe pupillaire à la lumière
Portuguese Provas de reflexo pupilar, Provas de reflexo pupilar à luz
Japanese 瞳孔対光反射試験, ドウコウタイコウハンシャシケン
Czech Testy červeného reflexu
English Light reflex tests pupillary, Pupillary light reflex tests
Hungarian Pupilla fényreflex vizsgálatok, Pupilla fény reflex vizsgálatok
Spanish Pruebas del reflejo pupilar
German Pupillenlichtreflextests

Ontology: Swinging flashlight tests (C0858381)

Concepts Diagnostic Procedure (T060)
Dutch bewegend flitslichtonderzoek
French Swinging flashlight test
German Swinging-flashlight-Test
Italian Test con luce lampeggiante in movimento
Portuguese Provas de cintilação rítmica
Spanish Pruebas de destellos oscilantes
Japanese 交互対光反射試験, コウゴタイコウハンシャシケン
Czech Testy reakce zornic na střídavý osvit
English Swinging flashlight tests
Hungarian Ingalámpa vizsgálatok