II. Background

  1. Drug resistance emerges rapidly
    1. Must be used with other antituberculous drugs

III. Indications

IV. Dosing

  1. Adult: 15-25 mg/kg PO
  2. Pediatric: 15-25mg/kg PO

V. Adverse Effects

VI. Monitoring

  1. Baseline
    1. Serum Creatinine
      1. Renal Dosing may be needed due to primarily Renal Clearance
    2. Visual acquity
    3. Color Perception
  2. Monthly retesting
    1. Visual acquity
    2. Color Perception

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