II. Efficacy

  1. As effective as Codeine for Cough Suppression
  2. But no more effective than Placebo in children
    1. Paul (2004) Pediatrics 114:e85-90 [PubMed]

III. Preparations

  1. Common component in Cold Preparations for Cough Suppression (e.g. Robitussin, Coricidin)

IV. Dosing

  1. Dextromethorphan (DM): 0.5 mg/kg up to 30 mg PO tid-qid
  2. Robitussin DM (15 mg/tsp)
    1. Adult: 2 tsp (10 ml) q4h
    2. Age 6 to 12 years: 1 tsp (5 ml) q4h
    3. Age 2 to 6 years: 1/2 tsp (2.5 ml) q4h

V. Adverse effects

  1. Abuse potential (esp. in teens)
    1. See Dextromethorphan Toxicity
    2. Bryner (2006) Arch Pediatr Adolesc Med 160:1217-22 [PubMed]
  2. Other (rare)
    1. Lethargy, stupor or coma
    2. Hyperexcitability
    3. Abnormal limb movements

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Cost: Medications

dextromethorphan (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
DEXTROMETHORPHAN ER 30 MG/5 ML Generic OTC $0.07 per ml
delsym (on 12/20/2023 at Medicaid.Gov Survey of pharmacy drug pricing)
DELSYM COUGH+CHEST CNGST DM LQ Generic OTC $0.02 per ml