II. Indications
III. Precautions
- See Long-Acting Beta Agonist
- Use in combination with CorticosteroidInhaler in Asthma
IV. Dosing
- See Single Maintenance and Reliever Therapy (SMART)
- Formoterol (Foradil)
- Rapid onset within 5 minutes (contrast 15-30 minutes for other LABAs)
- COPD, Moderate to Severe Persistent Asthma (age >=5 years)
- One inhalation every 12 hours
- Exercise Induced Asthma (age >=12 years)
- One puff 15 minutes before Exercise
- COPD Nebulized (Perforomist)
- Nebulize 20 mcg in 2 ml vial every 12 hours
V. Dosing: Formoterol with Inhaled Corticosteroid (ICS, for Asthma, COPD)
- Symbicort (Budesonide/Formoterol: 80/4.5, 160/4.5)
- One puff twice daily
- Dulera (Mometasone/Formoterol: 50/5, 100/5, 200/5)
- Two puffs twice daily
VI. Dosing: Formoterol with inhaled Long Acting Muscarinic Antagonist (LAMA, for COPD)
- Duaklir Pressair (Aclidinium/Formoterol)
- One puff twice daily
- Bevespi Aerosphere (Glycopyrrolate/Formoterol)
- One puff twice daily
VII. Dosing: Formoterol with inhaled LAMA and ICS (COPD)
- Breztri Aerosphere (Budesonide/Glycopyrrolate/Formoterol)
- One puff twice daily
VIII. Pharmacokinetics: Formoterol
- Onset <5 minutes
- Duration >4 hours
IX. Safety
- Pregnancy Category C
- Unknown safety in Lactation
X. Resources
- Formoterol Inhalation Capsule (DailyMed)
- Formoterol Perforomist
- Budesonide/Formoterol (Symbicort, DailyMed)
- Mometasone/Formoterol (Dulera, DailyMed)
XI. References
- (2022) Comparison of Asthma Medications, Presc Lett, #381217
- (2022) Inhaled Medications for COPD, Presc Lett, #381116
- (2020) Drugs for COPD, Med Lett Drug Ther 62: 137-44
- (2020) Drugs for Asthma, Med Lett Drug Ther 62: 193-200
- (2013) Presc Lett, 20(8): 43
- (2001) Med Clin North Am 43(1104):39-40 [PubMed]
- Wilson (2001) Chest 119:2021-6 [PubMed]
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Related Studies
| formoterol (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| FORMOTEROL 20 MCG/2 ML NEB VL | Generic | $5.08 per ml |
| symbicort (on 1/1/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| SYMBICORT 160-4.5 MCG INHALER | Generic | $22.80 per gram |
| SYMBICORT 80-4.5 MCG INHALER | Generic | $19.81 per gram |
| dulera (on 1/14/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| DULERA 100 MCG-5 MCG INHALER | $24.20 per gram | |
| DULERA 200 MCG-5 MCG INHALER | $24.12 per gram | |
| DULERA 50 MCG-5 MCG INHALER | $24.16 per gram | |
| perforomist (on 8/17/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| PERFOROMIST 20 MCG/2 ML SOLN | Generic | $5.08 per ml |
| bevespi aerosphere (on 1/1/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| BEVESPI AEROSPHERE INHALER | $36.52 per gram | |