II. Pathophysiology

  1. Enterobacter are facultatively anaerobic, highly motile, gas forming, Gram-negative rods in Enterobacteriaceae family
  2. Grouped with ESP Gram Negative Bacteria (Enterobacter, Serratia, Providencia)
  3. Colonizer of the normal human intestinal tract, and found in animal feces, sewage, soil, water, and dairy products
  4. Of the 22 identified Enterobacter species, only some are known to cause disease in humans
  5. Virulence factors
    1. Peritrichous flagella allows for high motility
    2. Increasing Antibiotic Resistance (including Carbapenem-Resistant Enterobacteriaceae)

III. Risk Factors

  1. Immunocompromised State (e.g. Diabetes Mellitus, Chemotherapy)
  2. Invasive medical devices

IV. Associated Conditions

  1. Nosocomial Infection
    1. Respiratory tract infections
    2. Urinary Tract Infections (esp. CAUTI)
    3. Surgical Wound Infections
  2. Uncommon cause of community acquired infections
    1. Urinary Tract Infections
    2. Upper Respiratory Infections
    3. Osteomyelitis
    4. Endocarditis
    5. Soft tissue infections

V. Resources

  1. Enterobacter Infections (StatPearls)
    1. https://www.ncbi.nlm.nih.gov/books/NBK559296/

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Ontology: Enterobacter (C0014344)

Definition (MSH) Gram-negative gas-producing rods found in feces of humans and other animals, sewage, soil, water, and dairy products.
Definition (NCI_CDISC) Any bacteria that is not assigned to the species level but can be assigned to the Enterobacter genus level.
Definition (NCI) A genus of Gram-negative, motile, facultative anaerobic, rod-shaped bacteria with peritrichous flagella in the phylum Proteobacteria.
Concepts Bacterium (T007)
MSH D004754
SnomedCT 58683007
English Cloaca, Enterobacter, Enterobacter species, Enterobacter (organism), Genus Enterobacter (organism), Genus Enterobacter, aerobacter, cloaca, enterobacter, Enterobacter Hormaeche and Edwards 1960, ENTEROBACTER, Aerobacter, Aerobacter, NOS, Enterobacter, NOS
French Aerobacter, Enterobacter
Swedish Enterobacter
Spanish género Enterobacter (organismo), género Enterobacter, Enterobacter (organismo), Enterobacter
Czech Enterobacter
Finnish Enterobakteeri
Italian Aerobacter, Enterobacter
Russian ENTEROBAKTER, AEROBACTER, ENTEROBACTER, ЭНТЕРОБАКТЕР
Croatian ENTEROBAKTER
Polish Enterobacter
Norwegian Enterobacter
German Aerobacter, Enterobacter
Dutch Enterobacter, Aërobacter
Portuguese Enterobacter