Acinetobacter Baumannii

Aka: Acinetobacter Baumannii

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II. Pathophysiology

  1. Acinetobacter Baumannii
    1. Aerobic Gram Negative Rod, similar to Pseudomonas
    2. Short rods (cocobacilli)
  2. Sources
    1. Soil
    2. Water
    3. Counter and other surfaces (survives for extended periods)

III. Associated Conditions: Nosocomial Infections

  1. Ventilator-Associated Pneumonia (and other Hospital Acquired Pneumonia)
  2. Central Line-Associated Bloodstream Infection (CLABSI)
  3. Infected Burn Injury
  4. Catheter-Associated Urinary Tract Infection (CAUTI)

IV. Labs

  1. Microscopy may be difficult (risk of misdiagnosis)
    1. Short rods may appear similar to cocci
      1. May appear Gram Positive
      2. On solid media, appear as diplococci (similar to Neisseria species)

V. Management: Antibiotics

  1. Empiric therapy in regions of low multi-drug resistance (<10-15%)
    1. Cefepime
    2. Meropenem
    3. Ampicillin-Sulbactam (Unasyn)
  2. Empiric therapy in regions of high multi-drug resistance (>10-15%, consider combination therapy)
    1. Ampicillin-Sulbactam (Unasyn)
      1. Sulbactam is sufficient alone if available
    2. Imipenem-Cilastin
    3. Meropenem
    4. Polymyxin B

VI. References

  1. Gladwin, Trattler and Mahan (2014) Clinical Microbiology, Medmaster, Fl, p. 94-5
  2. Sanford Guide, accessed on IOS 2/2/2025
  3. Ayoub (2020) Antibiotics 9(3):119 +PMID: 32178356 [PubMed]

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